Using a renographic unit of RDP 102 Type of Toshiba Co., renography was carried out in 10 controls, 48 patients with movable kidney, 15 hypertensives and 11 patients with glomerulonephritis. Movable kidney was diagnosed by pneumoretroperitoneum. Renal postural or respiratory displacement over 3 cm was regarded to be of movable kidney. And if patients with movable kidney had complications of hypertension or glomerulonephritis, they were excluded from the study objects. Before performing renography, a single dose of 300 ml of coarse tea or water was given orally to an examinee at hunger, and 30 minutes thereafter, 1 ml of
131I-Hippuran solution containing 0.5 μCi/kg was injected intravenously. Starting just before the injection, a renogram was recorded for 20 minutes in prone position. Two to five days thereafter, another renogram was recorded on the same examinee in the same way in standing position. Patterns of renograms were classified according to Machida's method, and semi-quantitative analysis of renograms was performed by measuriug total concentration (TC), minute concentration (MC), minute excretion (ME), 15-minute excretion (E
15), t
b, t
c and t
e according to Krueger et al, and Otake et al. Just after the recording renogram, voluntary urination was done to calculate urinary radioactivity. In all the examinees, renal biospy was undergone to get accurate diagnosis, and such examinations as routine urine tests, blood pressure, Fishberg's concentration test, PSP excretion test, GFR, RPF, FF and urea-clearance were carried out to understand the pathology of each examinee. The results obtained are as follows : 1) When the patient takes a standing position, the kidney may be displaced in sagittal direction, and so, the distance from the detector to the kidney may be different between prone position and standing position. Thus, a false renographic difference may be demonstrated between the prone position and the standing position. But, it was found that such a false difference could be neglected in practice. 2) The renographic difference between right and left kidneys is not found in controls either in prone position or in standing position, and so, all the right and left kidney can be united as a whole in this study. 3) In movable kidney and hypertension, Machida's pattern becomes worse in standing position than in prone position. In glomerulonephritis, the pattern does not always worsen in standing position, though it is already bad in prone position in many cases. 4) In movable kidney, TC, MC, and ME are not different from that in controls in prone position, but they become smaller by taking a standing position to show some disturbance of renal function. E
15 in movable kibney is smaller than that in controls even in prone position, and becomes smaller by taking a standing position. The postural changes of TC, MC, ME and E
15 are evident in postural movable kidney, though not found in respiratory movable kidney. Either in hypertension or in glomerulonephritis, ME and E
15 are smaller than in controls in prone position, and furthermore, MC is smaller than in controls in standing position. In hypertension, MC, ME and E
15 are smaller in standing position than in prone position. In glomerulonephritis, TC and MC are smaller in standing position than in prone position. 5) There is no correlation between the maximal renal displacement and the postural renographic change. 6) In hypertension, t
c and t
e are distinctly prolonged in standing position compared with prone position. 7) There is no relation between the postural change of urinary radioactivity count and that of reno-graphic excretion values. It is concluded that renographic patterns and values show more severe disturbances of renal function in standing position than in prone position in movable kidney. The same is the case with
抄録全体を表示