巻号一覧
15 巻, 1 号
選択された号の論文の5件中1～5を表示しています
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小時田 宏仂, 木村 隆一, 芦野 良橘, 斎藤 文彦, 安孫子 久明, 木村 武1973 年 15 巻 1 号 p. 1-10
発行日: 1973/01/30
公開日: 2010/07/05
ジャーナル フリーIn man, to be reported, there was natriuresis with weight loss, associated with the beginning of his fasting period. And it was suggested that adrenocortical androgen dehydroepiandrosterone (DNA) might play an important role in natriuresis induced by fasting. We investigated the rat's urinary excretion of sodium, potassium and DHA of the rats which were fasting with the injections of aldosterone 10 ag or DHA 5 mg/day. The rat plasma renin activity and renal renal renin contents were determined. The rat's excretions of sodium and potassium increased significantly at first day after rat's fasting, fasting with aldosterone and fasting with DHA injections, compared with the control rats. For the second, third and fourth days, the excretions of sodium and potassium decreased as it went by. All the rat plasma renin activity increased at fourth days after rat's fasting. The rat's DHA excretions of fasting and fasting with aldosterone injections were failed after the second day abruptly. Natriuresis of fasting could not cause in mineralcorticoid aldosterone and adrencortical androgen. DHA, for this two substances had never influences on the natriuresis of fasting in rat. The elevations of the rat plasma renin activity at the fourth days after fasting migh follow the changes of rat electrolyte levels by the rat's natriuresis of fasting. And it was obscure why the decreasing of the rat's DHAA excretions after the second fasting days were.抄録全体を表示PDF形式でダウンロード (1144K) -
岡 司1973 年 15 巻 1 号 p. 11-20
発行日: 1973/01/30
公開日: 2010/07/05
ジャーナル フリーHydrogen ion concentrations in the proximal and distal tubules of rat kidney were mesured byr quinhydrone microelectrode. The electrode was inserted into the tubule by means of micropuncture technic and pH was measured by Keitheley potentiometer. In the control group, pH of the proximal tubule fluid was 7.12∼7.38, slightly but significantly lower than that of the blood (7.36∼7.44). The difference in pH became more markedly in the distal sample of the tubule, being 6.30∼6.70. Under the HCO3 loading condition, pH values of both proximal and distal tubule fluids were elevated. In contrast, NH4CL loading experiment lowered pH values of the tubule fluids. Mannitol infusion lowered the tubular pH because of dilution of HCO3 concentration in the fluid. Acetazolamide increased pH of the proximal and distal tubule fluids because of its inhibitory effect on carbonic anhydrase.抄録全体を表示PDF形式でダウンロード (1187K) -
―螢光抗体法ならびにフェリチン抗体法による研究―吉沢 信行1973 年 15 巻 1 号 p. 21-31_6
発行日: 1973/01/30
公開日: 2011/07/04
ジャーナル フリーPresence and localization of antigenic sites in glomeruli of 14 patients with acute poststreptococcal glomerulonephritis (AGN) were studied by immunofluorescein and immunoferritin tecniques. Labelled IgG fractions from the same patients were used for the identification of antigenic sites. The staining capacity of these IgG fractions depended on the time when sera were obtained. Staining was minimal during the first week, and increased up to the 3 rd-4 th week. Glomeruli, however, stained only when renal tissue was obtained during the early phase of the disease. Precise localization of antigenic sites was determined with ferritin conjugated patient's Ig G. Segmental deposition of ferritin was observed in the mesangial matrix and in the endothelial side of the glomerular basement membrane. Subepithelial electron-dense deposits contained no, or only very few ferritin particles. In contrast ferritin conjugated antihuman IgG was distributed diffusely in the mesangial matrix, on the endothelial side of the basement membrane and in subepithelial deposits. These findings suggest that during the early stage of acute poststreptococcal glomerulonephritis, free antigen is present in the glomeruli of patients with this disease.抄録全体を表示PDF形式でダウンロード (17344K) -
I. Effects of toxic substances in the uremic blood on PAH uptake and ATP-ase activity of rabbit renal cortex.Katutaro Shiayama, Kazunori Ebihara, Tadatosi Shinozaki, Keizo Shida1973 年 15 巻 1 号 p. 33-48
発行日: 1973/01/30
公開日: 2010/07/05
ジャーナル フリーPDF形式でダウンロード (1286K) -
鈴木 唯司, 常松 定夫, 成瀬 克邦, 白岩 康夫, 舟生 富寿1973 年 15 巻 1 号 p. 49-54_4
発行日: 1973/01/30
公開日: 2010/07/05
ジャーナル フリーIschemic renal tubular injury was produced in rats by the temporary occulusion of renal pedicle. Occulusion was maintained for 10, 30, 60 and 90 minutes. The morphologic changes were studied by electron microscopy. The changes associated with 30 and 60 minutes of occulusion of renal pedicle were swelling of cells, increased vesicles, vesiculation of endoplasmic retidulum and swelling of mitochondria with vesicular cristae. After 90 minutes, mitochondvia were "packed" in the cells, and extraceilular compartment developed considerably. All changes occured in the proximal and distal tubules. The loop of Henle or collecting duct showed only a little changes. They might be manifestation of tubular necrosis. But it is provable that these hydropic changes indicate the considarable increase in the permeability of the tubular membrane. So, we discussed about relationship beween increased reabsorption in renal tubules and anuria in acute renal failure.抄録全体を表示PDF形式でダウンロード (16430K)
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