The studies on the movement of the seminal vesicle and spermatic duct using experimental animals have been reported by many investigators.
Pre and post ejaculatory rentgenograms, examinations of the removed seminal vesicles and spermatic ducts, and quantitative studies of the divided seminal contents have been also played the parts of the studies, but there have been a few reports concerning the ejaculatory movement of the human seminal vesicle.
I using an image intensifier, have been radiating a harmless little dosis of X-ray to the human seminal vesicle and observing the poured contrast media passing into the human seminal vesicle from spermatic duct and the movement of the seminal vesicle and spermatic duct in the exciting stage, ejaculatory stage and post-ejaculatory stage by X-ray cinematogram.
I have succeeded to take a 16mm cinemato graph and acquired new findings as follows:
1) Passing of the poured contrast media.
The contrast media poured into the spermatic duct may flow in the seminal vesicle through the ampullar portion of the spermatic duct, and then fill the body and vertex of the seminal vesicle gradually.
The contrast media filling enough in the seminal vesicle, then may flow in the posterior urethra namely: Graf's phenomen may reveal positive in all cases.
2) Movement in excitement.
Being excited sexually by masturbation, the seminal vesicle may be placed horizontally on account of raising of the beginning of the ejaculatory duct. The spermatic duct and ampullar portion may disappear its normal serpentine feature and appear extremely tense.
3) Movement in the beginning of ejaculation.
Horizontal seminal vesicle may return again to original position by means of descent of the beginning portion of the ejaculatory duct. After a while the feature of the spermatic duct and ampullar portion may disappear, while the seminal vesicle may move up and down for 2 or 3 times, then the first ejaculation may be begun.
4) Movement in ejaculation.
Ejaculatory movement may be summarized as follows; the first is an equal wall-contraction of the seminal vesicle its self, the second is a pendulous peristaltic movement which may occur from vertex of the seminal vesicle to the beginning of the ejaculatory duct, and the third is an up and down movement which may occur only once on the ejaculation.
5) Post-ejaculatory movement.
When the ejaculation may come to an end, the seminal vesicle may be relaxed, so the contrast media may be stayed in the seminal vesicle and dilate it.
While the feature of the spermatic ampulla may be reappeared. It may be caused by back-flowing of the contrast media which stayed in the beginning of the ejaculatory duct.
After then there may not be more movement of the seminal vesicle and spermatic duct visible.

抄録全体を表示

Peritoneal irrigation has been recognized as a treatment to compensate renal function in acute anuria. This method was first devised by Ganter (1923) and developed by others. Odel has reviewed the results from 101 clinical cases.
Recent development of surgical approach to the kidney made it possible to perform partial nephrectomy. This would be done without any trouble in the case with bilateral kidney. However, considerable caution should be employed in the case with unilateral kidney, because of the occurrence of anuria resulting from disturbance of the renal blood supply by operative procedures.
In the present study peritoneal irrigation was applied as overcoming temporary anuria due to partial nophrectomy. The results obtained were as follows;
1) When peritoneal irrigation was used, experimental rabbits survived more than one year after the resection of 72 to 73% of the unilateral kidney.
2) Partial nephrectomy was tried clinically in 5 patients with unilateral kidney. The following portion of the kidney was excised: one, 1/3 of the center; one, 1/2 of the lower pole; three, 1/3 of the upper or lower pole. All patients have now lived several years postoperatively having normal range of N. P. N. and blood electrolytes.
3) Peritoneal irrigation was employed in one case of anuria followed by blood transfusion of different type. It was started at the 4th day of anuria and stopped at the 6th day of irrigation by the request of the family. The patient died next day. Another one was anuria which appeared to be due to food intoxication. Irrigation was started at the 7th day. Urinary excretion began at the second day of irrigation and the patient recovered.
4) The rational irrigating solution was prepared considering composition of serum of the patients. An adequate velocity of irrigating and temperature of fluid were established.

抄録全体を表示

A case of hepatorenal syndrome (liver injury associated by kidney damage) treated by artificial kidney is reported. And review of the historical development of the hepatorenal syndrome and acute tubular nephrosis is presented, with emphasis on the clinical and pathological manifestations.

抄録全体を表示

This is a case of 45 year old female admitted on December 17, 1956 to Nagasaki Citizens' Hospital. She has been suffering of pyelocystitis for about a half year prior to her admission. On December 4, 1956, she complained of colic pain in the left ureteral region associated with fever sensation. The episode was followed by hematuria for four days. Left renal function decreased. X-ray examination revealed dilatation of the left renal pelvis and ureter. X-ray film could not demonstrate any concremet. At operateon a foreign body in form of grass measuring 13cm in length was detected in the lower part of the left ureter. Exact location was between the second physiological narrowing of the left ureter and the ureteral orifice. We think that she introduced it through the urethra into the bladder, during urination and bladder contraction the end of foreign body happened to be introduced into the ureter and that the sagittate character upon the stem caused it to work its way during muscular movement and peristalsis upon the ureter.

抄録全体を表示

Myxosarcoma of the bladder is veay rare disease. In Japan only four cases of it were hitherto reported.
S. F. one year and nine months old boy was first seen Nov. 19. 1955. The patient had had urinary frequency and small interrupted stream. Occasional dribbling for one month.
General physical examination was negative except for distended bladder. Catheterization yielded 150cc of clear residual urine. By rectal examination a small-egg-sized hard tumor was palpated at the bladder neck region. Cystoscopy disclosed a round tumor mass in the right side of trigone. At the surface of the tumor dilated vessels and fibrin membrane were seen.
X ray showed a irregular shadow of tumor at the bladder base. Suprapubic cystotomy was done on Nov. 28 and part of the tumor was extirpated. The tumor was friable and could easily be plucked by finger tips.
Pathological report showed myxosarcom of the bladder. On the fifteenth postoperative day a part of the remaining tumor came out of the wound, and on the 62th day on the occasion of adbominal pressure great tumor mass prolapsed from there. No effect was obtained from X ray radiation. Local injection of Nitromin was some benefit for the relief of pain.

抄録全体を表示

A case of granulomatous tumor of perineal ectopic portion of Denonvilliers' fascia in a man of 68 years is to be presented. This diagnosis was made at excision of the tumor and firmly established after operation by radiogram and histological examination. In a review of the literature no evidence of a similar case could be found.

抄録全体を表示

Recently a various problems about male sexual organs and their accessory glands have been studied actively. Fructose test for the determination of fructose in semen, ability of sperm fructolysis and distribution of SH-group were studied by me for this purpose. The relationships between SH-group and fructolytic ability or sperm motility were submitted to the consideration and applicated to the clinical uses and animal experiments. It was found that SH-groups have a close relation to the secretory function of male sexual organ, particularily to the sperm, which may conduce to the diagnosis of the disorders of the male sexual system, selection of treatment and evaluation of therapeutic effect. Variation of fructose contents and SH-groups etc. in a various conditions enforcing some artifical stress was investigated clinically and the following results were obtained, (I adopted Roe's new-method for the determination of fructose, Huggins and Talalay's method for acid phosphatase, Flesch's method and amperometric titration for SH-groups, spectrography for inorganic ions, and Barrnett's method for the histochemical staining of SH-groups.)
1) Epididymal sperms may move in the isotonic solution simply, but in the 0.5% fructose-Ringer-phosphate-buffer solution, they may move more actively. Moreover the motility of the epididymal sperms may be activated by adding glutathion to them.
2) Glutathion accelerate sperm fructolytic action in aerobic and anaerobic conditions. Inhibition of Thiol' agent by SH compounds appears markedly in aerobic condition.
3) By histo-chemical and biochemical examination, it is noticed that SH-compounds may be secreted mainly in the epididymis and seminal vesicles.
4) Male sexual hormone may accelerate the secretory function of the accessory glands and promote sperm protection and maturity by means of stimulation of epididymal cells. Metabolic regulator of the epididymal sperms may also be stimulated by it and fructolytic action increases consequently i. e. sperms are activated remarkably.
5) As sperms start moving, the fructolytic action appears and SH-group in sperm decreases, while SS-group increases at the same time. SS-group in sperm mostly consists in the neck and middle piece of moving sperm which may be a motive center of the sperm.
6) In my present studies, fructose contents in seminal plasma were 3.0mg/cc in normal human being, 2.8mg/cc in case of neurasthenia sexualis, 2.9mg/cc in case of oligospermia, 3.5mg/cc in case of azoospermia, 1.6mg/cc in case of hemospermia and 2.9mg/cc in the punctured fluid from seminal vesicles.
7) SH contents in the semen were 0.84mg/dl in normal human being, 0.89mg/dl in case of neurasthenia sexualis, 0.63mg/dl in case of oligospermia, 0.49mg/dl in case of Azoospermia, 1.44mg/dl in case of hemospermia, 6.9mg/dl in the punctured fluid from seminal vesicles and 2.5mg/dl in the prostatic secretion.
8) By split ejaculate method, semen may be ejaculated in order of prostatic secretion, sperm and seminal secretion, but prostatic secretion may be ejaculated out of order. Fructose consists in the last half of the ejaculated semen and the sperm is directly proportional to SH-contents.
9) SH-group has some relation with sperm by the consecutive ejaculation. The sperm is mostly preserved in the amplar glands.
10) The contrast medium in the vasoepididymo-vesiculography has a spermicidal action by means of inhibition of SH-group.
11) In case of hemospermia, the movement of the sperms may be interrupted in early stage. It may be caused by the lack of fructose and SH group due to the secretory disturbance of the seminal vesicles. In addition, 18 kinds of cation in the semen were demonstrated by spectrography, so more metal ion contents in the semen of hemospermia may have a spermicidal action.
12) In case of vasectomy, the secretion of fructose in the seminal vesicles is not affected, but the secretion of the SH group decreases.

抄録全体を表示