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4 巻, 4 号
選択された号の論文の12件中1～12を表示しています
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田辺 達三1975 年 4 巻 4 号 p. 195
発行日: 1975/08/15
公開日: 2011/10/07
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C. JOHN, M.D. NORMAN, 高場 利博, 桜井 靖久1975 年 4 巻 4 号 p. 197-203
発行日: 1975/08/15
公開日: 2011/10/07
ジャーナル フリー我々は10年来原子力人工臓器の研究に携わってきたが, 原子力左室補助ポンプの 2種類のシステムがようやく仔ウシによる生体実験の段階に達した. 二つのシステムは120g, 1600キューリーのPu-238 (酸化プルトニウムの形) を含有する核熱源を用いている. 第一のものは, 電子的に制御された, 弁もシールもない蓄熱式往復エンジンで, 制御のための情報は, ホール効果型センサーによって得られる. 第二の左室補助システムはポンプ駆動用の高い水圧に変換されるガス高圧をつくるのに核崩壊によって生じる熱を利用している. エンジン効率は7～16%に達し,ポンプ効率の計測値は85%が得られているこの両システムを生体の左心室といかに同期するかが解明されてきた. 初期の短期間 (175時間) の埋込み実験によって本法の可能性が明らかにされ, ンステムの改良と平行した生体実験の長期間実施が期待されている. しかしなお, 効率向上, 信頼性向上, 性能の向上, 小型化など多くの懸案が残されている.抄録全体を表示PDF形式でダウンロード (6136K) -
駒井 喬, 中薗 昌明, R. CLOESMEYER, R. KIRALY, 能勢 之彦1975 年 4 巻 4 号 p. 205-212
発行日: 1975/08/15
公開日: 2011/10/07
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特に早期血栓の形成過程について竹林 淳, 鎌谷 正博, 中上 健, 片山 善嗣, 林 宏輔, 柳 善佑, 十倉 寛治, 浅田 健蔵, 喜瀬 一登1975 年 4 巻 4 号 p. 213-219
発行日: 1975/08/15
公開日: 2011/10/07
ジャーナル フリーThe direct cause of the early thrombotic occlusion of a vascular prosthesis implanted to the infrarenal inferior vena cava (IVC) of dogs must be a septumlike thrombus that begins to form on the proximal anastomotic line immediately after implantation. Monitoring of the blood flow in the IVC by means of a Doppler flowmeter convinced us that the proximal end-oriented reverse blood flow, which was found to synchronize with inspiration, contributes to the cause of the formation of the “septum”
Observations also suggested that. whatever position the animals assume, the state of thrombus lining the lumen is influenced by gravity, since the flow in the IVC is slow and blood cell constituents therefore tend to settle in the lower part of the prosthesis.抄録全体を表示PDF形式でダウンロード (3402K) -
上出 健二, 真鍋 征一, 佐藤 公彦, 浜田 勝生, 宮崎 重1975 年 4 巻 4 号 p. 220-225
発行日: 1975/08/15
公開日: 2011/10/07
ジャーナル フリーThe marginal ability was estimated in a comprehensive manner on a ultrafiltration type artificial kidney (UAK) produced by us (named as Mark II). Here, we utilized screen filter typei. e., straight porous cellulose acetate membrane as a filter in UAK. By some preliminary fundamental experiments 0.09μ was found to be optimum as pore size for membrane of UAK in order to get a maximum flow rate under the condition that the concentration of protein was less than 10% of that of blood serum.
Mark II having effective filtration area of 100 cm2shows 40% in ultrafiltration rate of water and 4.3% in uric acid excretion, as compared with a human kidney, which has effective filtration area of 1m2in glomerulus. The concentration of total protein in the filtrate is 10% or less of the blood serum. Thus, Mark II has undoubtedly, to some extent, permselectivity with respect to molecular size, although the critical size of solute, which is filtrated through membrane, is much less than the average pore size of filter. This kind of permselectivity can be explained by the flow fractionation hypothesis.
As far as a simple UAK is concerned, metabolites in a human body can not be excluded in well-balanced manner. As comparative physiology suggests, the only remedy to this unavoidable drawback, is addition of other functionality to simple UAK, for example ultrafiltration/absorption type AK (a multifunctional AK).抄録全体を表示PDF形式でダウンロード (756K) -
―Intraaortic Balloon Pumping 法を中心として―岡田 昌義, 奥野 邦男, 飯塚 正史, 塩沢 拓男, 麻田 栄1975 年 4 巻 4 号 p. 226-236
発行日: 1975/08/15
公開日: 2011/10/07
ジャーナル フリーVenoarterial perfusion (V-A perfusion) and intra-aortic balloon pumping (IABP) as circulatory assistance were performed in dogs and also in 3 patients with cardiogenic shock following acute myocardial infarc-tion (AMI).
Both of these procedures were recognized to be useful methods to improve the hemodynamics in cardio-genic shock.
Especially, IABP could be performed for a long time with safety and simplicity. That is, balloon catheter (single, double, or triple balloon) was placed retro-grade through a femoral artery or a common iliac artery into the descending thoracic aorta just distal to the left subclavian artery.
Phasing of the device was accomplished by an external console utilizing the electrocardiogram to trigger inflation of the balloon during ventricular diastole and deflation during ventricular systole. Pumping system was Cordimat IIIa made in Germany, and carbon dioxide was used to inflate the balloon.
In dogs with cardiogenic shock induced by coronary artery ligation more than in normal dogs, an increase in diastolic blood pressure, coronary blood flow, max dp/dt, as well as a decrease in LVedp were obvi-ously revealed during IABP.
Besides, hemodynamic changes during IABP were observed by using single, double and triple balloon. Consequently, it was considered that triple balloon should be recommended in clinical use.
On the other hand V-A perfusion was, clinically performed with hemodynamic improvement during 160 min. in one patient and IABP was done effectively during 21-52 hours in two patients with cordiogenic shock due to AMI.
It could be concluded that these circulatory assistances were available methods in patients with cardiogenic shock secondry to AMI prior to direct coronary surgery.抄録全体を表示PDF形式でダウンロード (12288K) -
酒井 圭輔, 久保田 宏, 村上 忠司, 斎藤 明子, 館田 邦彦, 柴田 淳一1975 年 4 巻 4 号 p. 237-243
発行日: 1975/08/15
公開日: 2011/10/07
ジャーナル フリーHeart valve replacement utilizing the Björk-Shiley aortic and mitral prostheses was performed upon 27 patients at this institution between April 1971 and October 1974. The experience with 23 patients receiving this prosthesis and the follow-up from 5 months to 36 months was presented.
Ages ranged from 9 to 59 years (average: 38 years). All patients except one were either functional class III or IV by the New York Heart Association criteria.
Surgical mortality for the entire series was 26%. The late mortality was 9%. One patient who received aortic and mitral valve replacement had thromboembolism to the orifice of left coronary artery postoperatively unfelated to the prosthesis, which was documented by autopsy. The pressure gradient across the valve was almost same as the other reports. The hemodynamic results with this prosthesis was satisfactory. Hemolysis was minimum and the serum LDH at one year postoperative was only 1.3 times of the control value.抄録全体を表示PDF形式でダウンロード (849K) -
庄村 赤裸, 中村 正人, 滝川 喜一, 草川 実, 吉栖 正之, 庄村 東洋, 千種 弘章, 田中 久米夫, 吉川 純一1975 年 4 巻 4 号 p. 244-249
発行日: 1975/08/15
公開日: 2011/12/02
ジャーナル フリーDiagnostic echocardigraphy developed rapidly in these several years, and many reports have reviewed the echocardiographic characteristics of the implanted prosthetic valves.
This study investigates the application of echocardiography in the diagnosis of the function of implanted prosthetic valves, by marking observation of the echocardiographic motion pattern of various type of pros-thetic valves in patients.
In the cases with prosthetic mitral valves, it was able to diagnose that the disc motion was disturbed by thrombus and fibrogranulomatous tissue on the strut and suture ring, but it was not able to find that the disc motion was not disturbed but valve had thrombus on the only part of the disc. The former were found in three cases; one Kay-Shiley valve, one Starr-Edwards metal disc valve, one Bjark-Shiley valve. The latter were found one case; one Kay-Shiley valve.
In the cases with implanted prosthetic aortic valves, it was difficult to observe its total excursion, because the echo beam is at right angles to the valve motion when the echo transducer is placed at conventional position for obtaining an echocardiogram of the normal mitral valve. And the aortic valve was not able to trace from the supraclavicular fossa.
Echocardiography is useful for assessment of prosthetic mitral valve function, it is able to examine noninvasively, raedily and repeatedly again and again. Patients with prosthetic valves should be followed by echocardiography comparing initial echocardiogram recorded postoperatively as soon as potsible with seril observation in order to assess more accurately.
But, it is dangerous to diagnose by echocardiogram alone the prosthetic valve malfunction, so it is nece-ssary to evaluate it whole clinical data and clinical findings抄録全体を表示PDF形式でダウンロード (9914K) -
岩 喬, 三崎 拓郎, 佐藤 博文1975 年 4 巻 4 号 p. 250-252
発行日: 1975/08/15
公開日: 2011/10/07
ジャーナル フリーDuring open-heart surgery electrically induced ventricular fibrillation is now widely used to produce instantaneous still heart and also to prevent air emboli. We produced a new electrode which is non-traumatic to the heart, not bulky and easily bented. The electrode, which is made of stainless steel, and wires are embeded in silicone rubber. This device does not disturb the operative field because of its shape and softness and needs lower voltage compared to other electrodes formerly used.抄録全体を表示PDF形式でダウンロード (2513K) -
中林 宣男1975 年 4 巻 4 号 p. 253-257
発行日: 1975/08/15
公開日: 2011/10/07
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水戸 廸郎1975 年 4 巻 4 号 p. 258
発行日: 1975/08/15
公開日: 2011/10/07
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阿岸 鉄三, 太田 和夫1975 年 4 巻 4 号 p. 260
発行日: 1975/08/15
公開日: 2011/10/07
ジャーナル フリーPDF形式でダウンロード (86K)
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