Journal of Advanced Science
Online ISSN : 1881-3917
Print ISSN : 0915-5651
ISSN-L : 0915-5651
19 巻 , 1+2 号
選択された号の論文の6件中1~6を表示しています
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Paper
  • Noriyuki SUMIDA, Haruyuki SONOBE, Takashi OHYAMA
    2007 年 19 巻 1+2 号 p. 22-28
    発行日: 2007年
    公開日: 2007/11/21
    ジャーナル フリー
    We have shown previously that a left-handed curved DNA segment of 180 bp (T20) can activate eukaryotic transcription. Here, the local chromatin structure around the promoter was investigated in a HeLa cell line HLB10/T20 harboring the T20-containing reporter and in its control cell line HLB10 in which T20 was deleted from the same reporter locus. An analysis of translational positioning of nucleosomes indicated that the nucleosome density in the region spanning from about -500 to +200 relative to the transcription start site (+1) was lower in HLB10/T20 cells than in HLB10 cells. The results of the chromatin analyses also indicated that the histone core may slide within the T20 region, and the ability of T20 to capture and reposition histones may increase the accessibility of both the TATA box and other cis-DNA elements. These effects seem to be responsible for facilitation of transcription by T20.
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  • - 不安定領域に対する傾斜角度と冷却水温の影響 -
    Yasuyuki SATA, Moriaki WAKAKI, Shigeki OKINO, Fujio SUDA
    2007 年 19 巻 1+2 号 p. 29-35
    発行日: 2007年
    公開日: 2007/11/21
    ジャーナル フリー
    The flow instability in a rectangular natural convection loop was investigated focusing on its displacement angle and the cooling water temperature.Unstable chaotic temperature oscillation with flow reversal has occurred in silicone oils KF96-1 & -2 as well as in water, but in the case of water (cooling water temperature Tc=30°C) the unstable state starts at the transitional region from laminar to turbulent, while in the case of silicone oils (Tc=20 & 30°C) it does after the laminar becomes turbulent. It has been found that on the effect of displacement angle θ0 the unstable state occurs in | θ0 | <2°, narrow relatively to in the case of a toroidal loop, and that on the effect of cooling water temperature, the lower it is, the narrower the region of unstable flow.
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