Nippon Saikingaku Zasshi
Online ISSN : 1882-4110
Print ISSN : 0021-4930
ISSN-L : 0021-4930
Volume 33, Issue 5
Displaying 1-4 of 4 articles from this issue
  • Intraintestinal Toxin Production in Infants and Broiler Chickens
    Genji SAKAGUCHI
    1978 Volume 33 Issue 5 Pages 673-680
    Published: September 25, 1978
    Released on J-STAGE: February 19, 2009
    JOURNAL FREE ACCESS
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  • Yuko TODOME
    1978 Volume 33 Issue 5 Pages 681-688
    Published: September 25, 1978
    Released on J-STAGE: February 19, 2009
    JOURNAL FREE ACCESS
    Cyclophosphamide (Cy) was administered to Hartley strain guinea pigs by the intraperitoneal route. It was examined for effects on RRBC- and EAC-rosette formation of lymphocytes and on migration and incorporation of 14C-glucosamine of macrophages of the guinea pig. The effects of Cy on the responsiveness of lymphocytes to mitogens and on the development of delayed-type hypersensitivity were also studied.
    1. RRBC-rosette forming cells in the thymus decreased remarkably in number after the injection of Cy.
    2. When 5 or 10mM/ml Cy was added in vitro to peritoneal macrophages of guinea pig treated in vivo with Cy, the migration and incorporation of 14C-glucosamine of macrophages were inhibited remarkably.
    3. Thymic, splenic, and lymph-node cells showed a decrease in response to PHA and ConA after the administration of Cy. All of them, except thymic cells, showed also a decrease in response to LPS.
    4. Cy was examined for effect on PPD-induced proliferation of lymphoid cells from guinea pigs immunized with BCG by the aid of 3H-TdR incorporation. The proliferation was inhibited obviously by administration of Cy 24hr prior to, or 24hr after, the sensitization with BCG. No inhibition was observed when Cy was given to animals 8hr prior to, or 8hr after, the sensitization with BCG.
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  • Shinzi HISANAGA, Minami MASE, Akira MIZUNO, Yoshiaki HAYAKAWA, Takashi ...
    1978 Volume 33 Issue 5 Pages 689-696
    Published: September 25, 1978
    Released on J-STAGE: February 19, 2009
    JOURNAL FREE ACCESS
    When spores of Bacillus natto were inoculated onto meat extract agar, almost all of them germinated at about 20 minutes of incubation at 37C, and the outgrowth phase finished at about 120 minutes.
    Some of the spores of B. natto incculated into the ligated loops of the ileum in dogs were able to germinate, but died after germination. When inoculated into the ligated loops of the colon, spores failed to germinate.
    Some of the spores were able to germinate, but died after germination in a medium prepared from the heated (120C for 20 minutes) or unheated contents of the ileum. When cultivated in a medium prepared from the heated contents of the colon, almonst all the spores germinated, but not when cultivated in a medium prepared from the unheated contents of this organ.
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  • Zensaku YOSHII, Shuhei TANAKA
    1978 Volume 33 Issue 5 Pages 697-699
    Published: September 25, 1978
    Released on J-STAGE: February 19, 2009
    JOURNAL FREE ACCESS
    Download PDF (2913K)
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