Nippon Saikingaku Zasshi
Online ISSN : 1882-4110
Print ISSN : 0021-4930
ISSN-L : 0021-4930
Volume 42, Issue 4
Displaying 1-4 of 4 articles from this issue
  • Tatsuo YAMAMOTO
    1987 Volume 42 Issue 4 Pages 627-651
    Published: July 25, 1987
    Released on J-STAGE: February 19, 2009
    JOURNAL FREE ACCESS
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  • Yoshiki OBANA, Takeshi NISHINO, Teruo TANINO
    1987 Volume 42 Issue 4 Pages 653-661
    Published: July 25, 1987
    Released on J-STAGE: February 19, 2009
    JOURNAL FREE ACCESS
    The virulence of gram-negative organisms was studied in experimentally alloxan-induced diabetic mice. There was no significant difference in the mortality rate between normal and diabetic mice when intraperitoneally challenged with any of E. coli, K. pneumoniae, S. marcescens and P. aeruginosa with or without hog gastric mucin. Diabetic mice, however, proved higher susceptibility to urinary tract infection with either of P. mirabilis and S. marcescens and pulmonary infection with K. pneumoniae than nondiabetic controls. The function of polymorphonuclear cells and macrophages from normal and diabetic mice was investigated. Chemotactic activity of both phagocytes and phagocytic activity of macrophages from diabetic mice were lower than those from normal ones. These findings suggest that the increased susceptibility to bacterial infections of diabetic mice can be affected by the bacterial strain and infecting route.
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  • 1987 Volume 42 Issue 4 Pages 663-689
    Published: July 25, 1987
    Released on J-STAGE: February 19, 2009
    JOURNAL FREE ACCESS
    Download PDF (3649K)
  • 1987 Volume 42 Issue 4 Pages 690-698
    Published: July 25, 1987
    Released on J-STAGE: February 19, 2009
    JOURNAL FREE ACCESS
    Download PDF (1142K)
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