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Volume 44 (1989)
- Issue 6 Pages 757-
- Issue 5 Pages 705-
- Issue 4 Pages 649-
- Issue 3 Pages 585-
- Issue 2 Pages 533-
- Issue 1 Pages 53-
Volume 44, Issue 2
Displaying 1-3 of 3 articles from this issue
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Yoshikazu OHTSUBO, Masumi FURUKAWA, Yumiko FUJINOBU, Nobuko SUGIMOTO, ...1989 Volume 44 Issue 2 Pages 533-539
Published: March 25, 1989
Released on J-STAGE: February 19, 2009
JOURNAL FREE ACCESSA mycolic acid-containing glycolipid, trehalose-2, 3, 6'-trimycolate (GaGM), derived from Gordona aurantiaca, an acid-fast bacterium closely related taxonomically to Mycobacterium, was investigated for its immune adjuvant activity on cell-mediated responses in the mouse. I.V. injection of liposomes containing GaGM enhanced the generation of cytotoxic T-lymphocyte (CTL) against syngeneic and allogeneic tumor cells. In addition, the injection of GaGM augmented the natural killer (NK) activity and the antibody-dependent cellular cytotoxicity (ADCC).
These results suggest that the injection of GaGM induces the production of interleukin-2 (IL-2), since such effector cells as CTL, NK and K cells have been shown to require IL-2 for their development.View full abstractDownload PDF (791K) -
1989 Volume 44 Issue 2 Pages 541-557
Published: March 25, 1989
Released on J-STAGE: February 19, 2009
JOURNAL FREE ACCESSDownload PDF (2554K) -
1989 Volume 44 Issue 2 Pages 558-571
Published: March 25, 1989
Released on J-STAGE: February 19, 2009
JOURNAL FREE ACCESSDownload PDF (2028K)
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