巻号一覧
18 巻 (1989)
- 4 号 p. 165-
- 3 号 p. 95-
- 2 号 p. 35-
- 1 号 p. 1-
前身誌
18 巻, 2 号
選択された号の論文の7件中1～7を表示しています
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青木 芳和, 光田 慶一, 河野 雅弘, 伊藤 啓1989 年 18 巻 2 号 p. 35-41
発行日: 1989/08/31
公開日: 2012/11/27
ジャーナル フリーThe effects of oral administration of??-naphthylisothiocyanate (ANIT) on the microsomal membrane structure of rat liver were studied using the spin-labeling technique. Two different spin probes, 16-doxyl-stearic acid (16-DSA) and 5-doxyl-stearic acid (5-DSA), were used to assess the membrane fluidity. The rotational correlation time (τc) of 16-DSA decreased linearly, but temperature dependently, after ANIT administration; while it decreased sigmoidally in the control. Moreover, the levels of?Nc after ANIT administration were always shorter than those of the control between 22.5 and 37.5°C. On the other hand, the order parameter of 5-DSA incorporated in the ANiT-treated membrane did not differ distinctly from that of the control. These results suggest that ANIT or its metabolites injured the microstructure of the hydrophobic region rather than the surface region of the lipid bilayer in the membrane.抄録全体を表示PDF形式でダウンロード (798K) -
徳永 賢治, 土居 修, 宍野 宏治, 村瀬 光春, 武内 望, 篠原 力雄, 石黒 伊三雄1989 年 18 巻 2 号 p. 42-48
発行日: 1989/08/31
公開日: 2012/11/27
ジャーナル フリーThe levels of superoxide dismutase (SOD), lipid peroxide (LPO) and ceruloplasmin in sera and synovial fluids were determined in rheumatid arthritis (RA), osteoarthritis (OA) and infectious arthritis (IA),
Total SOD, Cu, Zn-SOD activity and LPO level in synovial fluid from patients with RA and IA were found to be remakably higher than from OA, hower, Mn-SOD activity showed no difference.
The SOD activity in serum from RA was singnificantly lower than OA, but the LPO value Showed no difference.
Ceruloplasmin levels were increased in serum and synovial fluid from RA.
These results suggest that synovial fluid measurment may be useful in clinical evaluation of chronic inflammatory disorders.抄録全体を表示PDF形式でダウンロード (895K) -
野崎 修, 大畠 恒子, 大場 康寛, 森山 弘之, 加藤 芳男1989 年 18 巻 2 号 p. 49-54
発行日: 1989/08/31
公開日: 2012/11/27
ジャーナル フリーWe developed a method for measuring urinary 17 ketosteroids (17 KS) without prior hydrolysis of its conjugated forms. Both free and conjugated forms of 17 KS were successfully extracted by passing the samle through a BSA-ODS minicolumn (TSK), eluting with 80% methanol and drying. After the Zimmermann reaction, the Zimmermann chromogen was extracted with 1-butanol. Our proposed method gave rapid results for urinary 17 KS and showed good reproducibility (C. V.: 2.41-8.75%), recovery (about 100%) and correlation with the conventional method for determining 17 KS (r=0.881, a regression line, y=0.565x+4.52, n=25).抄録全体を表示PDF形式でダウンロード (746K) -
白兆 洲, 陜 鴻林, 李 秋月1989 年 18 巻 2 号 p. 55-58
発行日: 1989/08/31
公開日: 2012/11/27
ジャーナル フリー中国における各種民族の健常人6708例の尿中アミラーゼアイソザイムパターンを分離検討し, 新しいアイソザイムパターンを発見した。この新しいパターンは異型 (Amylare-1s) アイソザイムと顕型 (dominont Amylase-2) アイソザイムの両者を有していた。私たちはこの新しいパターンを異顕型 (mixed type) と名付けた。家系調査の結果, 父は顕型で母は異型であって, 子供5人中に正常型, 顕型, 異型, 異顕型と4つの表現型が得られた。異型, 顕型共に常染色体性優性遺伝するとした過去の報告と一致し, codominont inheritanceのABO血液型と同じであった。抄録全体を表示PDF形式でダウンロード (1693K) -
鈴木 優治, 江原 進1989 年 18 巻 2 号 p. 59-62
発行日: 1989/08/31
公開日: 2012/11/27
ジャーナル フリーWe described a method estimating coexisting constituents which affect estimated value in the determination of various substances in body fluids. The principle of this method is based on the multiple regression analysis, by which the relationship between the concentrations of coexisting constituents and the difference between test method and comparative method was computed. Then, coexisting constituents contributing to the error were selected by the test of significance of partial coefficients. As an example of the application of this method, we studied the reaction of bromocresol green with serum protein fractions by cellulose acetate electrophoreiss.抄録全体を表示PDF形式でダウンロード (407K) -
青木 芳和, 小川 善資, 伊藤 啓1989 年 18 巻 2 号 p. 63-67
発行日: 1989/08/31
公開日: 2012/11/27
ジャーナル フリーThe ketone body ratio in the blood, the ratio of acetoacetic acid to 3-hydroxybutyric acid, reflecting the energy charge in hepatic mitochondria, is an indicator of hepatic functional reserve in chronic liver injury. In the present study, changes in the ketone body ratio in the blood were determined in rats with acute and subacute choiestatic liver injury induced with α-naphthylisothiocyanate (ANIT). The ketone body ratio in the blood was significantly increased 12-60 hours after a single administration of ANIT. When the dose of ANIT was increased to 50-200 mg Per kg of body weight, the ratio was linearly increased. When ANIT was administered for 15 consecutive days, the ratio was increased to twice that of the control after 6 days of administration and remained the same until the 15th day. Thus, in acute and subacute cholestatic liver injury, the ketone body ratio showed a compensatory increase uniike the case for chronic liver injury.抄録全体を表示PDF形式でダウンロード (593K) -
1989 年 18 巻 2 号 p. 68-75
発行日: 1989/08/31
公開日: 2012/11/27
ジャーナル フリーAs indicated at the outset of this report, the critical nature of the clinical requirements when blood gas testing is indicated, coupled with the labile nature of the sample and rapidly changing patient conditions makes it imperative that the analyst be aware of more than just the analysis it self Knowledge by the analyst, of the physiology of blood gas, the interpretation of basic blood gas results, the effects of the changing patient environment and the manner in which the sample is treated in a few short minutes from collection to reporting are equally important if one is to assure timely and clinically meaningful results.抄録全体を表示PDF形式でダウンロード (1049K)
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