Japanese Journal of Electrocardiology
Online ISSN : 1884-2437
Print ISSN : 0285-1660
ISSN-L : 0285-1660
Volume 32, Issue 5
Displaying 1-7 of 7 articles from this issue
  • Masao Yoshinaga, Masami Nagashima
    2013 Volume 32 Issue 5 Pages 427-435
    Published: 2013
    Released on J-STAGE: July 16, 2015
    JOURNAL FREE ACCESS
    Background : QT intervals were manually and automatically measured at the time of the primary screening in school-based cardiovascular screening programs. Using the longest QT interval among 12 leads as the representative QT interval for each individual is recommended, but no data is available regarding the difference in QT interval between manually and automatically measured QT intervals and for the lead (s) with the longest QT interval in the pediatric population. Methods : Subjects were divided into six groups, each consisting 100 children (both males and females) in the 1st, 7th, and 10th graders. QT intervals measured using the tangent line method were compared to the QT intervals automatically measured using the differentiation method in lead V5 in the electrocardiograms that were recorded in the screening program. The lead with the longest QT interval among 12 leads measured automatically was also determined. Results : The automatically measured QT intervals were significantly longer than the manually measured QT intervals in all groups, with the defference ranging from 21 to 26 msec. The longest QT intervals were present in leads V4 and V5 in 1st and 7th graders, and in leads V3 and V4 in 10th graders. Discussion : Screening for QT prolongation should be done recognizing that there is a difference between automated and manually measured QT intervals. Further studies are needed to determine the leads with the longest QT intervals in manual messuremant.
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  • Hirohisa Endo, Takashi Tokano, Takashi Shimizu, Hideki Wada, Shinichir ...
    2013 Volume 32 Issue 5 Pages 436-441
    Published: 2013
    Released on J-STAGE: July 16, 2015
    JOURNAL FREE ACCESS
    We present a case with azelnidipine induced symptomatic bradycardia. An 84 year-old female patient had begun taking azelnidipine at a daily dose of 16 mg for hypertension. One month later, she was admitted to our hospital complaining of dizziness and faintness due to bradycardia. Her electrocardiogram on admission showed sinus arrest with atrioventricular junctional escape rhythm at a rate of 40 beats per minute (bpm). Azelnidipine was immediately discontinued, and her heart rate was returned to sinus rhythm and 75 bpm the next day. An electrophysiological study was subsequently performed and maximum sinus node recovery time was 3,065 msec at a rate of 200 bpm. However, the blood concentration of azelnidipine at the time of admission was in the usual therapeutic range (7.89 ng/ml). Although azelnidipine does not show reactive increase in sympathetic tone following vasodilatation, there is no report of azelnidipine induced severe sinus bradyarrhythmia. We believe that latent sinus node dysfunction was unmasked by azelnidipine in this case.
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