Screening for gastric cancer with endoscopy in the aged residents of Niigata City started in 2003, in parallel with barium X-ray examination.
Over the course of 5 years, a total of 81,923 people underwent this endoscopic screening, in which a double-checking system for the interpretation of the endoscopic data and pictures by a committee was applied. During this 5-year period, 0.91% (821/90,041) of the people who received endoscopic screening were found to have gastric cancer.
The effectiveness of the endoscopic screening in reducing the false negative rate was appraised by investigating the records of the regional cancer registry.
The false negative rate in endoscopic screening during 2003 to 2004 was estimated to be 3.35% (7/209), which was lower compared with that in X-ray screening, 23.98% (44/185).
The death rates between patients who were diagnosed by endoscopic screening and and those who were diagnosed by X-ray screening over a period of 3 years were compared.
The gastric cancer death ratio during the 3-year period in the people who participated in the endoscopic screening in 2003 was 0.216% in males and 0.067% in females.
The gastric cancer death ratio in the X-ray screening was almost the same: 0.205% in males and 0.067% in females. On the other hand, the gastric cancer death ratio during the 3-year period in the people who had renounced both screenings in 2003 was 0.776% and 0.315%, respectively.
These data suggest that both endoscopic and X-ray screening for gastric cancer might have efficiently reduced the mortality of gastric cancer during the 3-year period.
In addition, the gastric cancer death ratio during the 3-year period in people who participated in the endoscopic screening and in the X-ray screening continuously in 2003 and 2004 was 0.00% and 0.23%, respectively. These results suggest that endoscopic screening might be more effective in reducing the mortality in the long term.
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