Conclusion :
Using grown-up rabbits, the writer got chronic CCl
4 toxicosis group by repeated buttock hypodermic injection of CC1
4, each time 0.025 cc, 0.05 cc, 0.1 cc per kg, twice a week, for 2 months or so, and another group got by injection of 25 mg/10 cc calcium mesotartrate, simultaneously with repeated injection of CC1
4, 0.05 cc, 0.1 cc per kg. The observation of these two groups on 'body weight, serum-elctrolytic quality, icteric index, hemoglobin, protein, etc. has led to the following results
: 1) On body weight ; Compared with the natural increase of that of contrasting group, CC1
4 toxicosis group showed rather decrease, but Calcium Mesotartrate injected group proved to have controlling effect on the decrease of body weight.
2) On serum-electrolytic quality; CC1
4 toxicosis group showed contra-relative phenomena against all kinds of ca, can, all kinds of mg, p, but by the injection of Calcium Mesotartrate, these contra-relative phenomena were observed to be inclined to disappear.
3) On hserum protein; CC1
4 toxicosis group showed remarkable lowering, but Calcium Mesotartrate injected group controlled the lowering, showing numerical value near to that of contrasting group.
4) On hemoglobin index ; CC1
4 toxicosis group showed rather low numerical value, but Calcium Mesotartrate injected group showed numerical value near to that of contrasting group.
5) On serious cases index ; CC1
4 toxicosis group continued to show high numerical value, and after 4 weeks or so, kept the almost fixed high numerical value, but Calcium Mesotartrate group was observed to be inclined to improve the numerical value.
Summing of these above is as follows ; In case of chronic CC1
4 toxicosis, ca
++n and all kinds of mg, are observed to stand in contra-relation and by administering of Calcium Mesotartrate, the writer has noticed a possibility of improving liver-disorder.
Therefore, the writer has found this medical substance (Calcium Mesotartrate) to be very promising towards the cure of other kinds of liver-disorder
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