To investigate the factor relating to the average life span (e0) in Japan, relationships of annual transitions and geographical differences in eo to numbers of medical personnel, institutions and others were studided with serial and geographical correlations, and the following results were obtained. 1) The serial correlation coefficients between e0 and numbers of medical institutions and others, the trends of which were excluded by linear regression, were positive and significant, so was the partial correlation coefficient between e0 for women and number of hospitals. These suggested that the relation between e0 and number of medical institutions was strong, especially for women, number of hospitals and annual transitions in e0. 2) The geographical correlation coefficient between number of pharmacists and e0 for men, and that between number of general clinics and eo for women were positive and significant, so was the partial correlation coefficient between number of pharmacists and e0 for men. These suggested that strong were the relation between number of pharmacists and the geographical differences in eo for men, and that between general clinics and eo for women. 3) The geographical correlation coefficients between annual changes in eo and numbers of medical personnel, institutions and others were positive and significant, so was the partial correlation coefficient between annual changes in e0 for women and number of public health nurses. In the multiple regression analyses of annual changes in e0 on items, numbers of pharmacists and public health nurses were selected in this order as the variables for men, so did numbers of public health nurses and general clinics for women. These suggested that strong were the relations of numbers of medical personnel, institutions and others, especially numbers of pharmacists and public health nurses for men, and public health nurses and general clinics for women, to the geographical differences of annual changes in e0.
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