Intake, excretion and distribution of cadmium in the HIMEDAKA Oryzias latipes were investigated using
109Cd. Fish were reared in Cd aqueous solution, in that coexisted with cysteine (CySH), in that coexisted with EDTA and in that coexisted CySH plus EDTA, respectively. The concentration of the chemicals was shown in Fig. 1. In the comparison of Cd distribution of the fish reared in sole existence of Cd, intake of Cd in the alimentary canal and depressed intake in the other viscera was observed under the coexitence of CySH. On the other hand, a remarkably depressed intake of Cd was observed under the coexistence of EDTA. The effect of CySH was cancelled in the simultaneous existence of EDTA. Fish were also reared in Cd aqueous solution, in Cd + CySH aqueous solution and in Cd + EDTA aqueous solution, respectively, for 72 hr. The concentration of the chemicals in this experiment was shown in Fig. 7. After the exposure, the fish had reared in Cd were transfered into distilled water, the fish had in Cd + CySH were into CySH aqueous solution and the fish in Cd + EDTA were into EDTA aqueous solution. The promoting excretion of Cd under the existence of these chemicals was observed. From the observation, a possible mechanism of effect of the coexisted chemicals was discussed.
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