巻号一覧
15 巻, 2 号
選択された号の論文の9件中1～9を表示しています
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安東 清1955 年 15 巻 2 号 p. 99-103
発行日: 1955/05/31
公開日: 2010/09/09
ジャーナル フリーPDF形式でダウンロード (882K) -
永見 忠孝, 井上 嘉明1955 年 15 巻 2 号 p. 104-107
発行日: 1955/05/31
公開日: 2010/09/09
ジャーナル フリー健康成年男子6名に葡萄糖並に果糖を注射して, 尿中枸櫞酸, Ca, pHの消長を調べ, 次の様な結果を得た.
1) 果糖並に葡萄糖の静注による尿中枸櫞酸の排泄量及び濃度の消長には, 小沢が血清枸櫞酸で見た様な, 又向山が同じくKrebsのサイクルの構成因子である尿中α-ケトグルタル酸で証明した様な一定の傾向が見られなかつた.
2) その原因は尿中枸櫞酸の排泄量及び濃度は尿中Ca, pH, 血清枸櫞酸の濃度等の複雑な因子の影響を受ける為と思われる.即ちCa排泄量の消長は尿中枸櫞酸と平行しないが両者の間には正の相関が証明され, 又pHの変動は極めて狭い範囲にあつたが枸櫞酸の排泄量と正の相関を示し, 更に血清枸櫞酸は腎クレアランスの変動を通じて尿中枸櫞酸の濃度に影響していることが両者の正の相関によつて証明された.抄録全体を表示PDF形式でダウンロード (596K) -
竹内 方志1955 年 15 巻 2 号 p. 108-129
発行日: 1955/05/31
公開日: 2010/09/09
ジャーナル フリーAs a contribution to elucidate the influence of streptomycin on the animal in the embryonal stage, the author investigated the calcium metabolism of the chick embryo employing fertilized eggs, and then studied the influence of streptomycin on the development of embryo. Further, when the influence of streptomycin on the calcium metabolism was investigated, similar experiment with calcium chloride was simultaneously conducted. The author also investigated the changes observed when these two substances were administered in combination, and then the data thus obtained were statistically analysed in an attempt to presume the mechanisms of the influence of streptomycin on the calcium metabolism of the animal in the embryonal stage.
Summarizing the data obtained in the above experiments, it was concluded that, the calcium content in the embryo was found decreased when the embryo was treated with a large amount of streptomycin alone, but the calcium content was found increased when the embryo was treated with an adequate amount of streptomycin. When the embryo was treated with calcium chloride alone, the excretion of calcium was found promoted, consequently, a decrease in the calcium content of the embryo was recognized. The decrease in the calcium content of the embryo caused by the treatment with calcium chloride was found aleviated by the combination with streptomycin at 18 days after the hatching. In every case, the calcium content of the embryo was found fluctuating roughly in parallel with the weight of the embryo.抄録全体を表示PDF形式でダウンロード (3077K) -
小沢 勝美1955 年 15 巻 2 号 p. 130-134
発行日: 1955/05/31
公開日: 2010/09/09
ジャーナル フリー健康な成年男子被検者5名に付き, 葡萄糖及び果糖を静脈内に注射し, 血清中の枸櫞酸カルシウム, 無機燐酸の消長を調べ次の様な結果を得た.
1.果糖注射後の血清枸櫞酸量は葡萄糖注射後の値に比べて上昇度が大きく, 叉葡萄糖注射では漸次減少し, 注射後120分では注射前の値よりも低い値を示している.
2.果糖及び葡萄糖注射により血清無機燐酸は減少するが, 果糖注射後には速かに注射前の値に復帰するのに, 葡萄糖注射では2時間後にも倚復帰しない傾向が見られた.
3.果糖及び葡萄糖注射に伴う血清カルシウムの変動は無負荷時の動揺に比べて有意な差異を示さなかつた.
4.以上の成績より, 日常治療に用いられる普通の果糖, 葡萄糖の少量の注射によつても, 血清中の枸櫞酸無機燐酸の時聞的経過に差異があり, 先人の報告による解糖過程及び他のKrebsのサイクルの構成諸因子の変動と綜合して観察すると, 果糖と葡萄糖の代謝経路には質的な相違があるものと推論される.抄録全体を表示PDF形式でダウンロード (627K) -
東郷 将1955 年 15 巻 2 号 p. 135-152
発行日: 1955/05/31
公開日: 2010/09/09
ジャーナル フリーAs a part of the pharmacological studies on the embryonal stage, the author investigated the influence of streptomycin on the development of chick embryo and its excretion into the allantoic fluid, thereby attempted to contribute to the elucidation of the fate of streptomycin in the living body. Furthermore, in order to investigate the toxicity of streptomycin, pathological histological examinations on the liver and kidney were simultaneously conducted. The following conclusions were thus reached.
1) An adequate amount of streptomycin slightly promotes the development of chick embryo and tends to demonstrate a diuretic action. At the higher concentration, however, the development is found even inhibited, and an inhibition on diuresis is recognized.
2) In view of the fact that the amount of streptomycin excreted into the allantoic fluid is extremely scanty showing only 0.4-0.9 of the amount injected, the major part of the amount of streptomycin injected is considered to be decomposed in the developing egg.
3) Streptomycin elevates the pH value of the allantoic fluid.
4) According to the pathological histological findings, streptomycin is considered to cause a fair damage in the liver and kidney of the chick embryo at a high concentration.抄録全体を表示PDF形式でダウンロード (8317K) -
CHIU YEE YAN1955 年 15 巻 2 号 p. 153-154
発行日: 1955/05/31
公開日: 2010/09/09
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浅川 春徳, 牧岡 蘇香, 柏倉 豊夫1955 年 15 巻 2 号 p. 155-158
発行日: 1955/05/31
公開日: 2010/09/09
ジャーナル フリーThe authors have recently given transfusions of dried blood plasma to 16 cases and experienced jaundice in relatively many cases (5 cases) . It is generally believed that the jaundice due to dried blood plasma transfusion is mild and transitional. Therefore, only very few reports concerning this disease can be cited. In this respect, the authors considered it necessary to present their report concerning the cases of jaundice experienced by them. Moreorver, they recongnized the necessity even more strongly because the preparation of dried blood plasma they administered was claiming not to give rise jaundice as it had been irradiated by ultraviolet ray. The authors would be very happy if the present report would become a profitable reference for the workers in the same profession.抄録全体を表示PDF形式でダウンロード (408K) -
林田 健憲1955 年 15 巻 2 号 p. 159-176
発行日: 1955/05/31
公開日: 2010/09/09
ジャーナル フリーIn an attempt to elucidate the influence of the substances of allithiamine group on the growth and development, the author, as the first step, planned to conduct a comparative examination of the influences of TPD and vitamin B1 on the general development of chick embryo. Simultaneously, the excretion of vitamin B1 into the allantoic fluid of the developing eggs treated with vitamin B1 or with TPD, and the total vitamin B1 content in the liver were examined, thereby the author attempted to get further clearer biological significance of TPD. The following is the results thus obtained.
No remarkable influence of vitamin B1 or TPD on the general development of chick embryo was recognized. However, when treated with a large dose, certain inhibition on the development was recognized, and a stronger inhibitive tendency was noted in the case of TPD.
The excretion of vitamin B1 into the allantoic fluid and the total vitamin B1 content in the liver were found increased by the treatment with vitamin B1 or with TPD. Especially, the excretion of vitamin B1 was found more strongly increased generally in the case of TPD. On the other hand, the total vitamin B1 content in the liver showed a tendency to be larger in the case of vitamin B1 compared with the case of TPD.抄録全体を表示PDF形式でダウンロード (8629K) -
西野入 尚一, 川北 利雄, 荏原 章悟, 太田 昭次郎, 中沢 進, 沼尾 欣一, 荏原 章悟, 村上 忠重, 酒井 朗, 渡辺 五郎, ...1955 年 15 巻 2 号 p. 177-179
発行日: 1955/05/31
公開日: 2010/09/09
ジャーナル フリーPDF形式でダウンロード (402K)
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