巻号一覧
18 巻, 2 号
選択された号の論文の7件中1～7を表示しています
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秋田 泰正1958 年 18 巻 2 号 p. 99-116
発行日: 1958/05/30
公開日: 2010/09/09
ジャーナル フリーThe excellent table of phase frequency response characteristics and amplitude frequency response without time-lag were constituted by using High-frequency system and the clinical connection of each wave of normal ballistocardiogram pattern was better equipped and new findings about it were obtaind.
High-frequency ballistocardiograph apparatus with the spring of high stiffness and the connected shoulder brace and foot brace was also constituted.
The charcteristics of this apparatus are controlling of the motion of the body developping by ballistic force and direct body pick-up system.
It was possible to make a recording of the same clear pattern without time-lag as the low-f repuency system by this method.
And the 3-dimentional ballistocardiograph apparatus was described in detail.抄録全体を表示PDF形式でダウンロード (26972K) -
第1編 白鼡の性周期について荒木 日出之助1958 年 18 巻 2 号 p. 117-127
発行日: 1958/05/30
公開日: 2010/09/09
ジャーナル フリーThe effects of a series of anti-tumor substances on ova in their early stage of development or having strong power of fission, ovum cells, spermatovum, or pregnant ova, and especially on the sex organs, their functions, and the reproductive functions of rats have been studied. The following results were obtained.
(1) Nitromin and Carzinophilin could control the sex cycles. Large dose of Azan could change the sex cycles in few cases.
(2) The minimum effective dose of Nitromin, Azan and Carzinophilin for the controll of sex cycles was 3.7 mg/kg, 100-200 mg/kg, and 838.9 u/kg respectively.
(3) The controling effect of sex cycles was transient, and they were recovered to the normal soon after the administrations were suspended.
(4) The body weight decreased remarkably when Nitromin or Carzinophilin was administered. On the other hand, it was rather increased when Azan was administered. The restoration of weight-loss nearly coincided with the recovery of the sex cycles. The changes of the body weight were related to the dose administered.
(5) Microscopic examinations of ovary and uterus of these rats were suggestive of the lack of estrus.抄録全体を表示PDF形式でダウンロード (3710K) -
第2編 家兎の排卵に及ぼす影響荒木 日出之助1958 年 18 巻 2 号 p. 128-138
発行日: 1958/05/30
公開日: 2010/09/09
ジャーナル フリーThe effects of Nitromin, Azan, and Carzinophilin leading to the artificial ovulations of rabbits have been studied. The following results were obtained.
(1) The ovulations of rabbits caused by Synahorin were partially inhibited when Nitromin had been administered. The minimum effective dosage of Nitromin was 15-25 mg. This effect was not seen when Azan or Carzinophilin had been administered.
(2) A remakable decrease of body weight was seen when Azan had been administered, while it did not in case of Nitromin or Carzinophilin.
(3) Atrophy was not seen in ovary when Nitromin had been administered while slight degenerations were seen in some ovum cells in cases of negative ovulation. In negative cases of Synahorin reaction caused by Nitromin administration, and in cases of large dose of Carzinophilin administration, the number of the ovum cells in the ovary was small, the density of the gland of endometrium was also small, the cavity was narrow and the arborescent changes were not seen or occurred slightly.
(4) It seemed that the inhibition of ovulation was due to the inhibition of Synahorin reaction to ovarium caused by anti-tumor substances.抄録全体を表示PDF形式でダウンロード (3986K) -
第3編 マウスの妊娠持続に及ぼす影響荒木 日出之助1958 年 18 巻 2 号 p. 139-149
発行日: 1958/05/30
公開日: 2010/09/09
ジャーナル フリーThe effects of anti-tumor substances on the pregnant ovum and foetus have been studied. The following results were obtained.
(1) Abortion may easily occur in the earlier the stage of pregnancy by administration of anti-tumor substances, or the more they were administered. Abortion occurred in 100 % in the early stage by administration of Nitromin with minimum effective dosage of 2.4 mg/kg. In the middle stage, the abortion occurred in 42.9% with 3.8 mg/kg, while 6.7% of it occurred in the last stage with the same dosage. The minimum safe dosage of Nitromin to bring the normal delivery was 21.7 mg/kg.
As for Azan, abortion was caused in 86.7% when it was administered in the early stae with the minimum effective dosage of 24.1 mg/kg: 66.7 % in the middle stage with 22.4 mg/kg: and none of it occurred in the last stage. The minimum safe dosage of Azan to bring the normal delivery was 256.3 mg/kg.
In the early stage of pregnancy the administration of 4, 878 u/kg Carzinophilin caused abortion in 42.8 %, while in the middle stage 40 % was caused with dosage of 6, 000u/kg, and in the last stage none of it occurred. The minimal safe dosage of Carzinophilin to bring the normal delivery was 10, 256.4 u/kg. No deformities were found on the foetus delivered normally.
(2) The necrosis, bleedings, and infiltrations of connective tissue in placenta remaining in the uterus were seen in cases of abortion. Atrophy of corpus luteum was seen in the ovary.
(3) The cause of abortion seems to be influences of anti-tumor substances on placenta, foetus and ovary of the maternal animal.
(4) No deformities were found.抄録全体を表示PDF形式でダウンロード (3603K) -
第1報 ガラクトースによる障碍度の定量的測定方法に関する研究大塚 礼三1958 年 18 巻 2 号 p. 150-156
発行日: 1958/05/30
公開日: 2010/09/09
ジャーナル フリーThe present paper deals with the studies of growth inhibitory power of galactose against the mutabile type variant of Murase made by the quantitative titration availing paper disk method.
Liquid agar containing the living organisms of the mutabile type variant of E. coli was poured on the agar plate and solidified. Mathod of the preparation of this agar plate is essentially the same as that employed in the cup method for the titration of penicillin unit. Namely, 0.01 cc of a galactose solution was pipeted out on a paper disk of 6 mm in diameter which was then placed on the above agar plate and incubated at 37°C for 24 hours in order to determine the diameter of growth inhibition zone around the disk.
Various factors possibly influencing the growth inhibiting power of galactose such as the number of organisms inoculated, kind of medium used, pH of the medium, , duration of time after placing the paper disk and before incubation, and the period of incubation etc were investigated in order to find out the minimal quantity of galactose necessary to give a positive growth inhibition zone.
Experimental results revealed that when 2 cc of a peptone water culture of the M variant is mixed with 98 cc of 1% peptone agar and 4 cc of this mixture was pured on 5 cc of peptone agar and solidified and then the paper disk is placed on it, such a small quantity of galactose as 1/640, 000 g con give a quite distinct growth inhibition zone after an incubation period of 24 hours.
Diameter of the inhibition zone was found to increase in proportion to the increase in the concentration of galactose.
Moreouer, some spontaneously derived galactose resistant variants develop in the zone of growth inhibition.
Further discussions on the present study will follow in the second report of this series.抄録全体を表示PDF形式でダウンロード (2444K) -
I. W0'株及びその変異株V1の細菌学的, 免疫学的性状について高山 康郎1958 年 18 巻 2 号 p. 157-170
発行日: 1958/05/30
公開日: 2010/09/09
ジャーナル フリーThe present paper deals with W-V variation of Salmonella typhi Ty 2 strain. A variant W0' obtained by low pressure cultivation from the Ty 2 strain of Salmonella typhi has characters exactly the same as those of the W-form of Ty 2 strain except that it produces a V-form variant V1 on the agar plate and that the colonies of W0' variant are apt to become irregular in size with growth and give a flower-like appearance by forming radiate opaque stripes. The striated colony consists of W0' organisms deficient of Vi capsule and V1 organisms possessing it.
W0' variant is separated from V1 in such a manner that the organisms of V1 are agglutinated by the addition of Vi antiserum and the agglutinated material is centrifuged at a low speed and the supernatant which contains a large number of W0' organisms is again centrifuged at a high speed. The purified W0' organisms thus obtained from the colony of W0' formed on the agar plate are devoid of Vi capsules. Accordingly, they are not agglutinated by Vi antiserum nor by a low pH concentration (lower than 3.25), and are low in virulence.
W0' organisms, therefore, are exactly the same as the organisms of W-form of Ty 2 strain except that V1 variant is constantly produced from W0' organisms when grown on culture media or probaly when grown in animal body.
In view of the above mentioned findings, it is concluded that Vi organisms are readily produced from W0' organisms. So that, Vi organisms are produced also in the colony of W0' following its growth and therefore the bacterial suspension prepared from the colony shows positive agglutination in either case of O or Vi antiserum in used giving an appearance as if the colony is a variant of VW-form. This phenomenon, further, demonstrates a W-V variation of Salmonella typhi which is regarded to be extremely rare or impossible to take place.
It was quite an interesting finding that almost no trace of Vi substance was detectable in individiums or in the suspension of purified W0' organisms demonstrating a picture completely different from so-called loss variation of the V-W variation. The present study will be supplemented by the second report.抄録全体を表示PDF形式でダウンロード (3960K) -
山本 常市, 市原 正雄, 小松 晃, 河合 正俊, 松井 勉, 佐川 文明, 堀 正雄, 成沢 達郎, 井上 康平, 八上 享司, 萩原 ...1958 年 18 巻 2 号 p. 171-174
発行日: 1958/05/30
公開日: 2010/09/09
ジャーナル フリーPDF形式でダウンロード (531K)
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