昭和医学会雑誌
Online ISSN : 2185-0976
Print ISSN : 0037-4342
ISSN-L : 0037-4342
24 巻, 8 号
選択された号の論文の4件中1~4を表示しています
  • 石田 賢三
    1964 年 24 巻 8 号 p. 307-324
    発行日: 1964/11/28
    公開日: 2010/09/09
    ジャーナル フリー
    The author collected f ourty three specimens of the stomach in the younger age from necropsy which died by other diesease than of the stomach. He investigated the frequencies of the following histological features in the mucous membrane as a) fibrosis, b) round cell infiltration, c) lymphatic fallicles d) intestinal epithelial metaplasia and e) erosive depression to compaire them with age. He has found that the features as a), d) and e) increase steadly with age, b) increases till five five years of age and thereafter becomes constant. The feature c) makes a special curve increasing to fifteen years of age and then decreases abruptly to 20 years without any flactuation in f urthor course. The frequency of those features differs markedly between the normal necropsied stomach and surgically resected stomach with chronic gastritis in the 3rd decade, but is nearly the same in 6th decade. Then it was concluded that the influence of the age must be highly estimated in the histological investigation of the stomach with chronic gastritis.
  • 山口 剛
    1964 年 24 巻 8 号 p. 325-334
    発行日: 1964/11/28
    公開日: 2010/09/09
    ジャーナル フリー
    Development of drug resistance in Mutabile-type variant and its heredity to further variants mutated from Mutable-type variant were investigated to elucidate if there could be any relations between drug resistance and galactose sensitivity in the same strains of Bact. coli.
    Results obtained were as follows:
    1. Six strains of Mutabile-type variant were obtained by mutation from the old broth cultures of 2 hundred strains of Bact. coli isolated at the time of admission.
    2. From the variant MT (galactose resistant variant mutated from Mutabile-type variant) and RT (so-called back mutant of Mutabile-type variant to original) were obtained by mutation. Furthermore, M' (galactose sensitive variant, just the same one as the starting Mutabile-type variant) was obtained from the RT by mutation.
    3. In the so-called O (original) →M→RT (MT) →M' mutation process it was investigated how the pattern of the drug resistance to various antibiotics can be transmitted to the next generation of mutation.
    4. Drug resistance of Bact. coli against streptomycin, chloramphenicol, tetracyclin and sulphathiazol were well transmitted to Mutabile-type variant and to the offspring mutated from it, whether it was the one possessed at the admission or the one developed by conjugation with the multiple drug resistant Shigella.
    5. Drug resistance of Mutabile-type variant developed also by repeated exposure to antibiotics in serial passages in broth.
    6. Inheritance of drug resistance was also demonstrated in S-R mutation of Bact, coll.
    From the above experiments it seemed that development of drug (SM, CM, TC and SA) resistance in bact, coli and its inheritance were of no relation to Mutabile-type variation of the same organism.
  • 山下 友義, 中島 康朝, 矢吹 栄佑, 土山 哲次, 永島 季男, 浮島 晤郎
    1964 年 24 巻 8 号 p. 335-345
    発行日: 1964/11/28
    公開日: 2010/09/09
    ジャーナル フリー
    Recently, as the progress of endocrinology, reported cases of adrenal cortical tumor are steadily increasing.
    Various opinions concerning the relationship between those tumors and endocrine activity are presented by many authors.
    Four autopsy cases of adrenal cortical carcinoma are reported.
  • 山下 友義, 中島 康朝, 清田 卓也, 土山 哲次, 浮島 晤郎
    1964 年 24 巻 8 号 p. 346-349
    発行日: 1964/11/28
    公開日: 2010/09/09
    ジャーナル フリー
    An autopsy case of primary osteoid chondrosarcoma of the left lung in a woman of seventy-four years old, presumably arising from the bronchial mesodermal tissue, is reported.
    The primary osteoid chondrosarcoma of the lung is surprisingly rare.
    A search of the literature reveals a similar case reported by Greenspan in 1933 and there is no other reported case at the present time.
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