昭和医学会雑誌
Online ISSN : 2185-0976
Print ISSN : 0037-4342
ISSN-L : 0037-4342
26 巻, 12 号
選択された号の論文の7件中1~7を表示しています
  • 竹内 方志, 古川 つねよ, 国保 喜寛
    1966 年 26 巻 12 号 p. 731-736
    発行日: 1966/12/28
    公開日: 2010/09/09
    ジャーナル フリー
  • 山家 忠幸
    1966 年 26 巻 12 号 p. 737-752
    発行日: 1966/12/28
    公開日: 2010/09/09
    ジャーナル フリー
    Studies were performed on the pattern of hemolysis and change of fraction of serum protein with the production of erythropoietin in the phenylhydrazine-treated rabbits, and following results were obtained.
    1. Hemoglobin concentrations, hematcrit and erythrocyte count showed marked decrease after starting the daily injection of phenylhydrazine and reached to the half level in their value by the fifth day.
    Reticulocyte count increased abruptly few days after starting injection.
    2. Decrease of albumin and increase of α2- and γ-globulin were seen as the degree of anemia enforced.
    3. Efforts were done for obtaining different level of hemoglobin concentration upon exanguination. Increased erythropoietin titer was obtained in 85.7 % of specimens with below 6.5 Gm/dl of hemoglobin concentration. However, elevated erythropoietin was seen in few subjects with those of over 6.5 Gm/dl of hemoglobin.
  • 第2報S型およびR型の免疫学的性状
    宮路 圭介
    1966 年 26 巻 12 号 p. 753-758
    発行日: 1966/12/28
    公開日: 2010/09/09
    ジャーナル フリー
    S-type of Z 27, Z 29 and R-type of Z 29 designated by this author were isolated from the strains of Lactobacillus acidophilus and their immunological characters were investigated by precipitation reaction both with so-called carbohydrate-antigen of Lancefield and with ordinary agglutination reaction.
    As the result of these experiments, following points were clarified :
    1. In precipitation reaction, no particular difference was observed whether the serum and the antigen are in homologous relation or in heterologous one.
    Howerer very slight lowering of the titre was observed in the reaction between S-type antigen and R-type serum or between R-type antigen and S-type serum.
    2. In agglutination reaction, no particular difference was observed in the titre among different strains of the species and between S-type antigen and R-type serum or R-type antigen and Stype serum.
  • 山口 仁
    1966 年 26 巻 12 号 p. 759-772
    発行日: 1966/12/28
    公開日: 2010/09/09
    ジャーナル フリー
    1. Levineの方法によつて, ラットに低酸素条件を与えて, その脳組織内におこった変化を研究した.
    2.低酸素条件において, 脳内に, 脳浮腫, 好気的解糖の抑制, リン酸に対する血脳関門の透過性の亢進がみられた.
    3.低酸素条件において, 脳内により多量にとりこまれたリン酸は, 無機リン酸の段階にとどまつていると考えられる.
    4.脳浮腫および血脳関門の変化は, ほぼ同様な経時的変化を示した.即ち, 低酸素状態を解除後, ある時間ののちに出現し, 数時間でピークに達し, 末期には, 過剰防衛反応によつて, 初期と逆の変化を示し, 二相性の経過をとつた.好気的解糖の抑制は, 低酸素状態解除直後にすでに出現し, 前2者より早い一相性の経過をとつて正常に復した.
    5.低酸素条件における可逆的な脳浮腫, 血脳関門の亢進, 好気的解糖の抑制などの現象について, 未だ十分に解明されていない脳浮腫, 血脳関門の機序に関する今日までの知見をもとにして, 考察を加えた.
  • 松岡 泰秀
    1966 年 26 巻 12 号 p. 773-799
    発行日: 1966/12/28
    公開日: 2010/09/09
    ジャーナル フリー
    The present study was designed to investigate the fetal electrocardiograms on 381 cases of the pregnant women.
    The abdominal bipolar lead was used in majority cases, but sometime the direct lead placing one electrode on the fundus of the uterus and the other electrode on the fetal head was applied.
    The fetal electrocardiogram started to be obtained in 15 out of 19 cases (78.9 %) as esrly as the first half of the fifth lunar month and 80-100 % of cases were able to record during the 6 th to the latter half of the 7 th lunar month. Then the rate of the cases for recording decreased until the end of the 8 th lunar month and increased to the rate of 93.8-100 % during the period of the 9 th and the 10 th lunar month.
    The decrease of heart rate, the prolongation of the QRS interval and the increase of the amplitude of the QRS complex were noted as pregnancy progressing.
    According to the direction of QRS complex the fetal electrocardiogram was classified into R pattern and S pattern. The R pattern was observed in 99.3 % of the cases with cephalic presentation and the S pattern in 61.9 % of the cases with breech presentation.
    The determination of fetal position was possible using the combination of vertical lead and horizontal lead.
    The frequency of various patterns of the QRS complex in the normal cases of with cephalic presentation was as follows : R pattern 51.8%, Rs 22.4%, qR 17.0%, qRs 1.7%, R. S 8.6 %, rS 3.4%, and S 10.3%.
    The heart rate decreased upon the fit of labor pains or the administration of pituitary posterior hormones, and increaced by oxygenating the mother. However, these factors did not induce any significant change on the QRS complex.
    In the reference to the Rs pattern and rS pattern, these were obtained in 53.8 % of the cases which had asphyxia and indicated the apgar index below 7, and in 24.5 % of the cases with coiling of the cord. These numbers were greater than those in normal cases.
    The QRS amplitude useing dinect lead from the fetal head was 1.8-3.5 times compared with the aplitude of leading from the abdominal wall.
    The large amount of hydramnions interf erred the recording of fetal electrocardiogram.
  • 湯藤 進, 北条 稔, 満岡 直, 羽山 忠良
    1966 年 26 巻 12 号 p. 800-807
    発行日: 1966/12/28
    公開日: 2010/09/09
    ジャーナル フリー
    Thirty years old man, was admitted with chief complaint of weakness, slight fever chest pain and backache.
    Positive physical findings were only spleenomegaly and marked enlargement of general lymphnodes which grew up gradually to form a mass as large as walnut in size.
    A numeral atypical large cell (6-8μ) in the peripheral blood were round or oval, its nucleus was irregular in its form and had a fine structure and from one to three numbers of nuleolei in each. These cells were assumed to belong to the cells of lympatic system based on the fact that cystoplasma was stained basophilic, showed positive PAS staining and negative peroxidase reaction with mcJunkin's method.
    This patient, diagnosed as leukemic lymphosarcomatosis on the basis of above observations, expired appoximately 6 months later when atypical cells appeared in 95 per cent in his peripheral blood.
  • 川澄 正一, 高橋 敬蔵, 五十嵐 義男, 松本 道, 細山田 明義, 張 志明, 川上 〓市, 藤川 純俊
    1966 年 26 巻 12 号 p. 808-813
    発行日: 1966/12/28
    公開日: 2010/09/09
    ジャーナル フリー
    Sodium γ-Hydroxybutyrate (OBA) was used as premedicants and the clinical effects were studied. Patients in relatively good risk, aged between 13 and 69, who had no association of illness, were selected for study at random. These patients were divided into three groups. The first group, the second group and the third group were given OBA 10-20 milligram per kilogram, OBA 66 milligram per kilogram and the placebo respectively. Each drugs were administered orally 1 1/2 hour prior to anesthesia induction and other no drugs combined. The effects were as follows;
    (1) In the first group, sedative effects were not evident. But 91.2 per cent in the second group were good sedated and there was no effect in the third group.
    (2) In the second group, patients exhibited many side effects such as exhausted feeling, heaviness in head, vertigo, nausea, headache, salivary secretion etc. It seemed that these side effects were mitigated by the combination with other drugs. For example, parasympathomimetic action was ameliorated with addition of belladonna.
    (3) There were no significant changes in blood pressure, pulse rate, ECG and minute volume.
    (4) The EEG pattern in subjects administering 66 milligram per kilogram of OBA resembled to those with natural sleeping pattern.
feedback
Top