昭和医学会雑誌
Online ISSN : 2185-0976
Print ISSN : 0037-4342
ISSN-L : 0037-4342
28 巻, 11 号
選択された号の論文の7件中1~7を表示しています
  • 高橋 敬蔵, 岩堀 嘉和
    1968 年 28 巻 11 号 p. 671-674
    発行日: 1968/11/28
    公開日: 2010/09/09
    ジャーナル フリー
  • ―特に消化器疾患に対する観察 (その1) ―
    坂本 利正, 山口 明志, 本多 平吉, 向後 健, 神田 修次, 天野 長久, 村山 義治, 大坪 芳臣, 秋田 泰正, 清水 晃, 太田 ...
    1968 年 28 巻 11 号 p. 675-681
    発行日: 1968/11/28
    公開日: 2010/09/09
    ジャーナル フリー
    A functional investigation of stomach, liver, gall-bladder and duodenum was carried out on the electrodermometer. In comparison with other clinical examination methods, the practical examinations revealed that this method could give results with in much shorter period, say about 5 minutes, without giving pains to the persons examined. It was also found that quite satisfactory results were obtainable with the electrodermometer as the screening examination method for diseases of these organs.
  • ―胃血管結紮による胃粘膜の変性および再生の経時的変化に関する病理組織学的研究―
    土山 哲次
    1968 年 28 巻 11 号 p. 683-695
    発行日: 1968/11/28
    公開日: 2010/09/09
    ジャーナル フリー
    An attempt has been made to the analysis of the damage of the gastric mucosa and its repair by regeneration in lesions of chronic gastritis and gastric ulcer. The animals used were Wistar rats. Three main arteries of the stomach, together with veins, were cut off and the neighboring organs and tissues were also seperated as thoroughly as possible. All rats were necropsied from 30 minutes to 55 days postoperatively. The acidity of the gastric juice at the time of sacrifice was determined by histamine test. The experimental results and conclusions were as follows.
    1) The damage of the gastric mucosa is mainly due to arterial ischemia, but venous factors, such as congestion, edema and so on, are partly concerned.
    2) The damage of the gastric mucosa occurs constantly at the f undic area, which is considered to be most differentiated. The damage begins symmetrically from the greater curvature gradually. At the lesser curvature, the f undic area adjacent to the fold-like ridge and the pyloric area near the duodenum are fairly well preserved. The areas are considered to be the site of the later regeneration of the mucosa. As to the extent of the damage of the mucosa at the pyloric area and the ampulla (Vormagen), there is considerable variation and no clear cut rules are present. This may be partly due to the variety of the vasculature and the manual skill of the ligation.
    3) Histologically the damage begins with degeneration and breakdown of parenchymatous cells of fundic glands followed by necrotic foci of varing depth and breadth. The spreading of necrotic area becomes most prominent on the 3rd or 4th day after operation. At the base of lesions leukocytic infiltration is marked and lesions are demarcated. Crusted necrotic foci fall off and denuded area (ulcer) is formed. The base of the ulcer is formed by inflammatory granulation tissue. As the result of the perforation of the entire gastric walls due to necrotic breakdown, the formation of the granulation tissue of foreign body type is also present till about the 20th day. The adhesion of the neighboring tissues and organs also takes place.
    4) About the 5th day the surface of the ulcer is gradually cleaned up, the regeneration of glandular epithelia from the remaining gastric mucosa occurs and the repair takes place. Both epithelial regeneration from the fundic and pyloric area are of f oveola gastricae type and resemble pyloric gland (uncomplete regeneration of the fundic area) .
    5) The regeneration of the gastric mucosa becomes prominent from the 7th or 8th day and the greater part of the surface of the ulcer is covered with newly formed epithelia on about the 15th day. About the 20th day the area of uncomplete regeneration becomes narrower and the fundic area spreads and this indicates the progress of the repair of the fundic parenchyma.
    6) The regeneration of the fundic parenchyma completes on the 30th day. But the gastric juice proves to be acid-free. The discrepancy between the nummerical recovery of parietal cells and the functional recovery of gastric acid secretion exists, but this discrepancy disappears on the 40th day, as histamine test is concerned.
    7) Chief cells regenerate in the latest stage and they are less in number. Intraplasmic thionine granules of regenerated chief cells are decreased in number. Whether or not the regeneration of chief cells is resulted from the differentiation from mucoid cells cannot be clarified by this experiment.
  • 藤井 浩一
    1968 年 28 巻 11 号 p. 696-717
    発行日: 1968/11/28
    公開日: 2010/09/09
    ジャーナル フリー
    A comparative study has been done on the efficiency of three different type of artificial heart-lung machine such as hypo-therm high-flow perfusion using disc-oxygenator, hypo-therm low-flow perfusion using small volume bubble and normo-therm high-flow perfusion using Showa University type.
    The studies was performed on fifty-three patients about the serum electrolytes, blood acidbase balance, post operative bleeding and others. The results were as follows.
    1) The disc oxygenator type required twice as much volume of blood as that of the other two. 2) There was no significant difference on serum electrolytes, blood acid-base balance and its transitions. 3) Post operative bleeding was least in the cases done by the Showa University type in comparison with the other two. 4) Mechanical hemolysis was higher in the bubble type oxygenater than that of the disc oxygenator. 5) Total peripheral resistance of the blood vessels during perfusion was highest in the small volume bubble type and no significant differences were seen between the other two. 6) Normo-therm high-flow perfusion needs no cooling or warming during operations and may shorten the partial perfusion time. 7) There were no significant differences in hemolysis, post-operative bleeding or postoperative urine volume by using 5 % D-W, Ringer's solution, low moleculer dextran or gelatin modified solution (Haemacell) as blood diluents. 8) When the 20 % mannitol was added in the diluents, an increase of the urine output was seen during and immediately after the perfusion, but no increase was seen at 24 hour post-operated period.
  • 橋本 敏夫, 加藤 国之, 石井 暢
    1968 年 28 巻 11 号 p. 718-720
    発行日: 1968/11/28
    公開日: 2010/09/09
    ジャーナル フリー
    A comparative observation was performed by “Azostix” and diacetylmonoxime method in order to determine blood urea nitrogen in about 100 cases. The results obtained showed that a satisfactory agreement was demonstrated between the two methods.
  • 西堀 実, 藤巻 悦夫, 安藤 公信, 清田 卓也, 鈴木 庸之, 川上 勝久, 永田 和弘, 渡辺 康
    1968 年 28 巻 11 号 p. 721-726
    発行日: 1968/11/28
    公開日: 2010/09/09
    ジャーナル フリー
    This interesting tumor develops from the normal neuromyoarterial glomus. Our cases were all womenn, one was 81 years old and other was 21 who were suffering from the pain of finger tip and lost many years until the tumor were completely removed surgically by our clinic.
    The glomus tumor is subunguinal in location in about half of the cases reported and the constant symptom of the tumor is sever pain, as our cases.
    The histological findings are divided into four types. Our cases belongs to the epithelioma type.
  • 福井 章, 菊池 敏夫, 大井 菫一, 小川 紀彦, 羽山 忠良, 風間 和男, 鄭 政男, 後藤 晃
    1968 年 28 巻 11 号 p. 727-733
    発行日: 1968/11/28
    公開日: 2010/09/09
    ジャーナル フリー
    A patient, whose blood cells lost an inagglutinability, was reported in the present paper.
    A 40-year-old male, whose blood group was A B, received large amount of blood transfusion (3, 100 ml) due to severe anemia. When he was admitted to our clinic after various treatment about 10 months, his blood group was noticed to be 0-group without anti-A and anti-B antibody. He died about 4 months later.
    The formalin-fixed liver and spleen was examined by agglutinin and absorption test and elution test. His blood group was confirmed to be AB group.
    The present case showed that the patient had originally AB blood group, however he lost A- and B-antigen in red cells during the clinical course, therefore, the blood group reacted like O-group.
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