昭和医学会雑誌
Online ISSN : 2185-0976
Print ISSN : 0037-4342
ISSN-L : 0037-4342
28 巻, 2 号
選択された号の論文の9件中1~9を表示しています
  • 小松 信彦, 山野 敦子
    1968 年 28 巻 2 号 p. 65-68
    発行日: 1968/02/28
    公開日: 2010/09/09
    ジャーナル フリー
    Whether or not the drug-resistance is transmitted between Lactobacillus and Escherichia coli was tested in the mixed culture. The results are as follows:
    1) In the mixed culture of streptomycin-resistant Lactobacillus and streptomycin-sensitive E. coli, the drug-resistance of Lactobacillus was not transmitted to E. coli.
    2) Also in the case of mixed culture of streptomycin-sensitive Lactobacillus and streptomycin-resistant E. coli, the resistant factor of E. coli was not transmitted to Lactobacillus.
  • 堀坂 和敬, 高橋 定子, 小野 真吏乃, 黒牧 武夫, 戸塚 耕二
    1968 年 28 巻 2 号 p. 69-76
    発行日: 1968/02/28
    公開日: 2010/11/19
    ジャーナル フリー
    角尾らは1963年にニワトリ脳髄10kgからAnserine (β-Alanyl-1-N-methylhistidine) を結晶状に単離し, 元素分析, 分解試験およびペーパークロマトグラフ法によって確認した.Anserineとこの同族体であるCarnosine, Ophidineは脊椎動物の筋肉に特異的に多量含まれるが, その意義については未だ明確なものが得られていない.われわれはこれらDipeptideの意義を究める手掛りを得るため諸種動物の脳内におけるDipeptideの分布を検索している.今回はニワトリ脳Anserineの微量定量法を吟味し, 次の結果を得た.
    1) 成長とともに脳重量が増加し, 脳Anserine: 量も増加するが1年齢になるとほぼ一定する.
    2) 脳の部位別Anserine量について, 視葉には大脳, 小脳に較べて高濃度に含まれる.
    2) 中枢に作用する薬物の投与によつて脳Anserine量は影響をうける.Chloropromazine投与により約50%の減少が認められるが, 脳中にはAnserineの分解産物とされる1-N-Methylhistidineの増加は認められなかつた.
  • 徳江 茂
    1968 年 28 巻 2 号 p. 77-85
    発行日: 1968/02/28
    公開日: 2010/09/09
    ジャーナル フリー
    角尾ら (1963) は10kgのニワトリ脳髄よりAnserine 0.4gを結晶状に単離し, 確認したが, その後カラムクロマトグラフ法による微量定量法を確立して成鶏脳中には1.96μmole/gのAnserineが含まれることを認めた.Anserineはニワトリ筋肉中に多量含有されるDipeptideであるが, その存在意義については明確なものがない.われわれは生体内におけるこのDipeptideの意義を明らかにする目的で種々の面から検討している.本報告においてThiamine欠乏がニワトリおよび脳Ansenine量におよぼす影響を検討し, 以下に述べる成績を得た.
    1.Thiamine拮抗物質であるOxythiamineの投与により脳Anserine量は著明に減少する.しかし脳中にはAnserineの分解産物とされる1-N-Methylhistidineは増量しない.
    2.Thiamine欠乏飼料の投与により体重の減少, 肝, 心および腎Thiamine量の著るしい減少が認められる.投与約3週後に脚弱による歩行障害を来たし, 5週後に昏睡状態に陥つた.
    3.昏睡状態時に脳Anserine量の減少を認めたが, 拮抗物質投与の場合のような著るしい減少を示すことはなかつた.
    4.筋肉中のDipeptide量にはThiamine欠乏による影響は認められなかつた.
    5.肝および心に組織学的異常所見を認めた.
  • ―手術療法を中心として―
    赤坂 裕, 今村 一男, 甲斐 祥生, 中西 欽也, 丸山 行孝, 菅 孝幸, 近藤 常郎
    1968 年 28 巻 2 号 p. 86-95
    発行日: 1968/02/28
    公開日: 2010/09/09
    ジャーナル フリー
    We have had experience with 264 patients suffering from urethral stricture between 1951 and 1966. During these years we have performed 19 surgical operations: 17 end-to end anastomosis, one Badenoch pull-through operation and one Johanson's operation. In each case of the end-to-end anastomosis and the Badenoch pull-through operation, urethral fistula was developed, but the former was corrected by a Stefan's operation and the latter by resuturing the original incision by chemotherapy. The other 16 cases were performed without complications. Furthermore, the patient who underwent the Johanson's operation is performing well at the present time, nearly 20 days after the operation.
  • 本多 俊晴
    1968 年 28 巻 2 号 p. 96-107
    発行日: 1968/02/28
    公開日: 2010/09/09
    ジャーナル フリー
    Bacteriologic and immunologic studies were made on the patients with chronic respiratory diseases. Patients were divided into three groups: bronchial asthma (group I), chronic bronchitis (group II), and other diseases which consist of bronchiectasis, pulmonary emphysema and pulmonary fibrosis.
    1. There was no sex difference among the three groups. Most patients of group I distributed on the ages from the third to the fourth decade; but in group II and III the number of patients increased as the age advanced.
    2. Streptococcus viridans and Neisseria were respectively found in 96 percent of the patients studied. Hemophilus group considered as an etiologic agent in chronic bronchitis were found in 56 percent of the patients under the study, while Staphylococcus aureus, Diplococcus pneumoniae, and Streptococcus hemolyticus were found in 16, 13 and 39 percent respectively. There was no significant difference among the three groups, except that the percentage of positive cultures of gram-negative bacilli in the sputum of the patients of group III was higher than the other two groups.
    3. In the sensitivity tests to antibiotics of pathogenic organisms isolated from the sputum, there was nothing specially to mention except for the more frequent detection of penicillin resistant Staphylococci in group III.
    4. About two-thirds of 37 strains isolated as Hemophilus group were identified as Hemop hilus influenzae by the requirement of V-facter and X-factor for growth, and by the agglutination test with specific antiserum. Thus it was thought that Hemophilus influenzae might be found in about 36 percent of the patients with chronic respiratory diseases.
    5. By means of transtracheal aspiration, the incidence of positive cultures of pathogenic organisms in the patients which were considered to have bronchial infection was much lower than the expectation.
    6. There was no remarkable difference among the three groups as to ASLO titer, and most of ASLO titers were below 166 units which was considered to be normal limit.
    7. There was no remarkable difference among the three groups as to ASTa (antistaphy-lolysin) titer, although group II showed a slightly high value than the other two groups.
    8. As to the titers of antibodies to Hemophilus influenzae, group II and group III showed higher value than group I. Most patients, in whom positive cultures of Hemophilus group were obtained in their sputum or throat, showed high antibody values. In view of this fact, it was thought that Hemophilus influenzae has much to do with the chronic infection of the respiratory tract.
  • ―一般健康者との比較―
    島田 信義, 高嶋 正士, 佐藤 礼子, 加藤 晴美
    1968 年 28 巻 2 号 p. 108-113
    発行日: 1968/02/28
    公開日: 2010/09/09
    ジャーナル フリー
    一般健康者と患者の神経質傾向の相違比較についての結果を要約すれば,
    1) 神経質傾向は全体をとおして患者群が高く, emotionよりはhealthにおおくみられる.すなわち, 男H=4, E=3, 女H=5, E=3となる (50%以下の項目数の集計) .これに対し, 一般健康者群は, 男H=2, E=0, 女H=2, E=0 (60%以下の項目数の集計) となり, 両者間に差がみられた.
    2) 40%以下の反応率を示すもの18問で, H=7, E=11で, ここではemotionに関するもの全体平均と比較しhealthよりもおおい.
    3) 20代, 30代女子患者に問題がおおく, 健康者群では, 女子よりも男子に, 患者群は男子よりも女子に問題が集中している (前者は10代, 60代以降に, 後者は20代, 30代に神経質傾向が高い) .
    4) 問題別から, 頻数のおおい項目は, 「身体のあちらこちらが痛い」, 「朝起きたときでも疲れたように感ずる」, 「なにか考えて眠れないことがある」, 「ときどき胃が痛む」の順でhealthに関するものがおおく, これは一般健康者群にもいえる.
    5) 患者群に集中的にみられる問題は, 「長い間不愉快だつたことがらを忘れることができない」, 「たびたび頭痛がする」, 「なんとなくいらいらする」, 「なにか原因のわからないことについて気にして心配する」などで, この場合H=1に対しE=3となる.
    6) 患者群で, 神経質的徴候を比較的おおく示す時期は, 男女ともに20代, 30代, 40代であり, 心身ともに不安と葛藤を含む時期ともいえる.
    7) いちがいに, 胃腸病は心理的な病気であつて, 神経質傾向が強いとまではいえないが, 少なくとも研究前に設定した「悩みや不安のあるものは胃腸が弱く, また, おかされ易い」という仮説は, ほぼ実証される.
  • 井原 正剛, 小泉 勝司
    1968 年 28 巻 2 号 p. 114-116
    発行日: 1968/02/28
    公開日: 2010/09/09
    ジャーナル フリー
    In the studies of Hypopyseal Triangles with Cynomolgus Monkeys, we carried out the comparative anatomy of the cranial carvature by hypopyseal point and by distance between the point and several other point with the species.
    From the view point of comparative anatomy, the mean distance of skull is 7.56±0.536 cm, and the mean distance between P and Br is 3.31±0.347 cm, P and H is 2.96±0.292 cm, and P and G' is 2.68 ±0.273 cm.
    The Cynomolgus Monkeys show P-Br, P-H and P-G' distance shorter than those of the Gibbon or the Dog.
  • 高橋 敬蔵, 細山田 明義, 佐伯 志明, 岩堀 嘉和, 會 瑞彦, 藤川 純敏, 早川 聿朗, 伊藤 啓之助, 鄭 彰雄, 熊谷 日出丸
    1968 年 28 巻 2 号 p. 117-120
    発行日: 1968/02/28
    公開日: 2010/09/09
    ジャーナル フリー
    Two cases of “probable” bronchospasm was experienced and analyzed in details in the present study.
    Plastic surgery of hand was performed on the two children who had the history of asthma bronchiale. Under general anesthesia with GOF (N2O: O2: Fluothane) the bronchospasm was suddenly appeared and was relieved by steroid hormone. Neither Atropine and Opystan as the premedicant nor Succinyl-choline and high concentiation of inhalated Fluothane were effective in prophylaxis or treatmeut of bronchospasm.
  • 鄭 彰雄, 高橋 敬蔵, 細山田 明義, 佐伯 志明, 會 瑞彦, 岩堀 嘉和, 早川 聿朗, 伊藤 啓之助, 神尾 鋭
    1968 年 28 巻 2 号 p. 121-125
    発行日: 1968/02/28
    公開日: 2010/09/09
    ジャーナル フリー
    This survey was made of endotracheal tube sizes in 1347 cases of infants and children under general anesthesia from January 1964 to July 1967 in Showa University Hospital.
    The endotracheal tubes employed here were of the portex and marked in French sizes.
    It was seen that used endotracheal sizes were influenced by age, body weight and height rather than by sex, muscle relaxants (SCC) and intubating approaches.
    The guide table of the optimal endotracheal tube sizes in pediatric anesthesia was offered.
    The authors were impressed that there was a considerable spread of the tube sizes particularly in 3 to 5 years old groups. Three tubes of different sizes prepared for intubation were occasionally not enough and more different size of tubes were required.
feedback
Top