昭和医学会雑誌
Online ISSN : 2185-0976
Print ISSN : 0037-4342
ISSN-L : 0037-4342
32 巻, 9 号
選択された号の論文の6件中1~6を表示しています
  • 井上 清恒
    1972 年 32 巻 9 号 p. 451-456
    発行日: 1972/09/28
    公開日: 2010/09/09
    ジャーナル フリー
  • ―特に, 子宮腟部ビランについて―
    小田切 光男
    1972 年 32 巻 9 号 p. 457-467
    発行日: 1972/09/28
    公開日: 2010/09/09
    ジャーナル フリー
    It is well known facts that tissue mast cells (TMC) contribute to maintain homeostasis by produce, storage and secration of heparin, histamine and serotonine. There has been so many reports discussing relationship between heparin and collagenous fibers, and histamine, serotonine and vascular function.
    The auther revieed 442 cases of biopsied portio vaginalis for past three years to detect distribution of TMC in various disease.
    All biopsied specimens are divided into the following three classification according to it's histopathological findings;
    (A) . erosio portionis (390 cases), (B) . dysplasia (4 cases), (C) . carcinoma (48 cases) . Erosio portionis is also divided inot following four classification and TMC is studied in earch group. Results are follow:
    1. Erosio portionis consists of 85% of psedoerosion and 15% of true erosion.
    2. The number of TMC/mm2in the so-called normal portio vaginalis is 114.79±65.13 stochastically. On distribution of TMC, there are no TMC in the mucosa but numerous TMC in the submucosal stromal tissue. TMC is frequently observed in the portio vaginalis from thirty to fourty decade.
    3. On the number of TMC/mm2in the erosio portionis, there are tendency of incressed in number of TMC compared to normal state like following; 153.18±72.81 in the erosio granulans, 138.30±53.57 in the erosio gladularis, 211.80±84.78 in the erosio papillaris, 161.24±87.08 in the erosio glandularis cystica. TMC is more frequently observed from fourty to fifty decade. On distribution of TMC in the tunica propria, TMC is recognized around fibrosis and erosive glands oftenly.
    4. In the portio vaginalis, TMC is appeared in the acute inflammatry state (erosio granulans) and more recognized in subchronic state (erosio papillaris) . On the contrary, TMC is disappeared in the settled stste of inflammation (erosio glandularis) . These facts suggest some defence capacity of TMC for maintaining homeostasis.
    5. The number of TMC/mm2in cases of dysplasia is 155.00±48.37, and no TMC is observed in the atypical squamous layer. However there are clumpings of TMC just beneath this layer.
    6. The number of TMC/mm2in the connective tissue around carcinoma is 128.50±93.78 but no TMC is seen in cancer nestitrelf.
    7. It is still obscure whether TMC has defence capacity against neoplastic proliferation or not.
  • 張 相天
    1972 年 32 巻 9 号 p. 468-493
    発行日: 1972/09/28
    公開日: 2010/09/09
    ジャーナル フリー
    Histopathological studies on Osseous Tissue in Newborn Infants with Special Reference to Correlation between the Development of Organs and Osseous Tissue in Various Regions.
    The present study was carried out on a total of 133 autopsy cases derived from dead fetuses and dead newborn infants collected at the First Department of Pathology, over a period of ten years. These cases were examined morphopathologically to clarify the degree of differentiation of osseous tissue in femur, sternum, rib, lumbar vertebra, and cranium.
    1. The osseous tissus of each bone was differentiated in proportion to the number of weeks of fetal life. Differentiation tended to begin at the 37 th week of fetal life. Rib and sternum showed still a somewhat low degree of differentiation at the 37 th week of fetal life and tended to become differentiated regularly in the following week. Of the cranial bones, the frontal bone was much less differentiated than the occipital and temporal bones at the 26 th week of fetal life. It began to be come differentiated rapidly at the 28 th week.
    2. The correlation between the differentiation of osseous tissue and the body weight at the time of birth was examined. As a result, the lighter the body weight was, the lower the degree of differentiation of this tissue was in the infant. There was a tendency for this tissue to be differentiated in almost all the infants weighing 2, 200 gm. at the time of birth.
    3. When the number of weeks of fetal life was equal, the larger the number of days of survivial, the higher the degree of differentiation of osseous tissue.
    4. Even when the number of weeks of fetal life was equal, the heavier the body weight at the time of birth, the higher the degree of differentiation.
    5. In fetuses affected with pulmonary atelectasis, hyaline-like membrane degeneration, serious deformity, and intracranial hemorrhage, the differentiation of esseous tissue was low in degree. There was no specific correlation between any other pathological change and the differentiation of osseous tissue.
    6. The less advanced the development of organs, the lower the degree of differentiation of osseous tissue. The more persistent the extramedullary hematopoietic focus, the lower the degree of differentiation of osseous tissue.
    7. Myeloid cell began to decrease in the 33 rd week, and nucleated erythrocytes began to decrease in the 38 th week. Thereafter they both tended to increase again.
    Myeloid cells, lymphocytes, reticular cells, and monocytic cells were higher in count, but nucleated erythrocytes were rather lower in the group of infected fetuses than in that of noninfected fetuses.
    From the results mentioned above, it is presumed that the degree of differentiation of osseous tissue is related mutually to the state of development of organs in the newborn infant.
  • 阿久津 恵美子, 市河 三太
    1972 年 32 巻 9 号 p. 494-500
    発行日: 1972/09/28
    公開日: 2010/09/09
    ジャーナル フリー
    The effects of new antispasmodic drug, n-butoxybenzyl hyoscyamine bromide (BHB) on the motility of bile duct and small intestine of guinea pig or rabbit were examined.
    1. Spontaneous contraction of the isolated bile duct was inhibited and tonus was. decreased by the administration of BHB at doses greater than 1×10-7g/ml. To provoke the spasmolytic effect, a dose of 1×10-6g/ml was necessary.
    2. Spasmus provoked by acetylcholine and BaCh were inhibited by BHB. Antispasmodic action of BHB against the evoked spasm by BaC12 was stronger than that against. the spasm by acetylcholine.
    3. The dose-response curves against the evoked contracture by acetylcholine and histamine and the antispasmoidic action of several antispasmodicus were shown in figures 2, 3 and 4.
  • 菅 剛猛
    1972 年 32 巻 9 号 p. 501-510
    発行日: 1972/09/28
    公開日: 2010/09/09
    ジャーナル フリー
    1) 0.5 ml/kg of phenylhydrazine hydrochloride was injected subcutaneously into rabbits every three days at a concentration of 2%, 4% and 8%, respectively.
    2) Edematous and colliquative changes in the malpighian tuft, swelling of Bowmann's capsule and pericapsular edema, vacuolar degeneration of the tubular epithelium and edema of the interstitium are related to hypoxemic change.
    3) The ultramicroscopic findings observed in the A group (2% solution) showed an irregular arrangement of the mitochondrial christae in the proximal tubular epithelium, as represented by a partial disappearance of the christae.
    4) The reddish homogenous lesion and colliquative change in the center of periphery of the Malpighian tuft appear to originate in the intercapillary region. Since these findings exceed the categoly of mesangial edema, such changes are best called intercapillary edema.
  • 与儀 洋, 鄭 彰雄, 松崎 史朗, 増田 豊, 宮田 拓雄, 細山田 明義, 高橋 敬蔵, 外丸 輝明
    1972 年 32 巻 9 号 p. 511-515
    発行日: 1972/09/28
    公開日: 2010/09/09
    ジャーナル フリー
    Clinical records of patients who were managed by anesthesiologist from January 1, 1967, through March 31, 1971, were studied.
    17 cases (female 15 cases, male 2 cases) of tetany occurring during anesthesia are presented.
    The tetany (carpal spasm) appeared 1 hour and 21 minutes after induction. Analysis of blood showed markedly respiratory alkalosis (pH 7.521, Paco2 22.9 mmHg) and normal serum electrolytes concentration. (Na, K, Cl, Ca, nonorganic phosphate)
    Administration of calcium gluconate 10-30 ml intravenously was not effective and contrary it disappeared without any treatment in the early stage of recovery from anesthesia.
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