Both exercise and chromium (Cr) exert beneficial effects on glucose tolerance. The mechanism by which exercise improves glucose tolerance may involve an alteration of Cr metabolism. To determine the effects of chronic exercise on urinary Cr excretion, we measured the effects of exercise tolerance on urinary Cr concentration in 30 healthy young women (aged 18-22yr). The subjects underwent a bicycle ergometer exercise test for 60min, and urine samples were taken prior to excerise, and less than 3h, 24, and 48h after exercise. Urinary Cr, copper, zinc, and nickel concentrations were measured at trace level by inductively coupled plasma mass spectrometry using a dynamic reaction cell technique. The changes in urinary Cr excretion were quite different among the three chronic exercise groups. In particular, the urinary Cr concentration (mean±SEM) prior to exercise was significantly higher in sedentary subjects than in trained subjects (4.53±1.14 and 1.33±0.17ng/mg urinary creatinine, respectively,
p<0.05). These data demonstrate that chronic exercise has no discernible impact on urinary Cr excretion after a single bout of exercise in young women and that hypokinesis leads to increased basal Cr excretion.
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