脳卒中
Online ISSN : 1883-1923
Print ISSN : 0912-0726
ISSN-L : 0912-0726
10 巻 , 6 号
選択された号の論文の9件中1~9を表示しています
  • 喜多村 孝一
    1988 年 10 巻 6 号 p. 463-467
    発行日: 1988/12/25
    公開日: 2009/09/03
    ジャーナル フリー
    The validity of surgical proceizures in the treatment of intracerebral hematoma was evaluated by a clinical study of 441 cases with intracerbral hematoma admitted to the Department of Neurosurgery, Tokyo Women's Medical College from 1980 to 1987.
    The author recognized that the degree of severity of pathological features influencing the prognosis varies with the individual case. From a biological point of view, the conventional clinical classification of patients with intracerebral hematoma is unreasonable and not available for the exact evaluation of therapy. However the evaluation of therapy is used to be done by estimating the prognosis of patients divided into several groups according to a classification formula. Such method of evaluation could not be justified, because of the classification of patients being artificial, and not biological.
    The conclusion is as follows. The removal of intracerebral hematoma by craniotomy, CT guided stereotactic aspiration of hematoma or ventricular drainage is an effective procedure at the therapy of intracerebral hematoma in the case of adequate operative indication and procedure by a skillful neurosurgeon.
  • 平野 朝雄
    1988 年 10 巻 6 号 p. 468-472
    発行日: 1988/12/25
    公開日: 2009/09/03
    ジャーナル フリー
  • 藤島 正敏
    1988 年 10 巻 6 号 p. 473-480
    発行日: 1988/12/25
    公開日: 2009/09/03
    ジャーナル フリー
    It has been known that hypertension is a major risk factor for cerebral infarction. Its relation has been discussed mainly on a static or morphological aspect, based on the epidemiological and clinicopathological studies, but rarely from a hemodynamic standpoint. In this paper, mechanism of development of cerebral ischemia in hypertension is discussed on cerebral hemodynamic aspect.
    Regional cerebral blood flows in the cortex and deep structures are reduced in hypertensive humans (measured by PET) as well as animals (measured by H2 technique), its reduction being related with the severity and duration of hypertension. In similar to normotensives, however, cerebral autoregulation is preserved in hypertensives, although its upper and lower limits are shifted to higher levels in hypertension. The lower limit shift is more rapid and great during development of hypertension in spontaneously hypertensive rats (SHR), followed by a gradual but progressive upward shift even in the established state of hypertension. Therefore, in aged and long-lasting hypertensives the autoregulatory range from blood pressure at rest to the lower limit level becomes narrower, indicating that cerebral blood flow easily reduces when blood pressure falls.
    Observing the blood pressure changes in patients who newly or recurrently develop non-embolic cerebral infarction during hospitalization, a greater reduction of blood pressure prior to attacks by antihypertensive treatment seems to play some role in the occurrance of cerebral infarction. In such cases, infarct is relatively large and sited mainly in the watershed area or in the cortical artery territory.
    These experimental and clinical data strongly suggest that a blood pressure lowering by treatment of hypertension beyond the lower limit of autoregulation, which significantly shifts upwards, appears to cause cerebral ischemia or infarction. Careful treatment, namely a more slow and less extensive reduction of blood pressure is recommended, and also choice of antihypertensive agents is important, vasodilating drugs being less harmful.
  • 森 和夫
    1988 年 10 巻 6 号 p. 481-490
    発行日: 1988/12/25
    公開日: 2009/09/03
    ジャーナル フリー
    I.頸動脈内膜切除手術 (CEA) の我が国の現況につき, 学会専門医指定訓練施設 (623施設) を対象にアンケート調査を行った (回収率54%).その結果, a) ほぼ40%の施設ではCEAの経験がなく, b) 昭和62年 (1987年) の年間推定手術件数は500件足らずに止まり, c) 無症状例に対する予防的CEAは行わないとする意見が過半数を占めていた.
    II.日本人の病変の特徴をあげ, 手術手技, 術後回復過程, 再狭窄の問題などにつき, 教室での基礎・臨床面での検討結果 (主に小野博久助教授による) の一部を紹介し, 併せてわれわれの考えている手術適応につき述べた.日本人向けのCEAのguidelineが必要である.
    III.CEAの安全性や有効性につき, 最近, 国の内外で盛んに論議がなされている.要は上手な手術を行い, surgical riskを自然歴とbalanceのとれるところまで抑え込むことにある.同時にCEAは全能の手術ではなく, 完成卒中の防止に対し過大な期待をもつべきでもない.
  • 鈴木 二郎
    1988 年 10 巻 6 号 p. 491-493
    発行日: 1988/12/25
    公開日: 2009/09/03
    ジャーナル フリー
    Cerebral stroke is an extremely common disease which strikes suddenly and leaves its victims in a seriously disabled state; its prevention remains a medical problem of the highest priority. Though the techniques for neurosurgical treatment following onset were already considered at the beginning of this century when the first surgical attempts were made, there is still room for significant developments in this area.
    Computed tomography and microsurgical techniques have become major weapons in the surgeon's armory and notable advances have been made in the surgical therapy of cerebral infarction and hypertensive intracerebral hemorrhage. However, the surgical treatment of cerebral stroke-whether due to aneurysm, AVM, or other mechanisms-has been limited to therapy during the chronic stage following onset; even today, surgical therapy for stroke is not universally accepted as appropriate.
    Nonetheless, toward the possibility of acute-stage treatment of cerebral stroke, further progress has been made possible by the emergence of magnetic resonance imaging, positron-emission tomography, and digital subtraction angiography, as well as advances in intravascular neurosurgery and the development of brain-protective agents. It has now become possible to save the lives of stroke victims in the acute stage following onset and to obtain favorable functional recovery.
  • 朝長 正徳, 平井 俊策, 玉岡 晃, 井原 康夫, 石原 得博, 内野 文彌, 山之内 博, 藤原 茂芳, 小林 祥泰, 岡本 幸市, 山 ...
    1988 年 10 巻 6 号 p. 494-512
    発行日: 1988/12/25
    公開日: 2009/09/03
    ジャーナル フリー
  • 萬年 徹, 長嶋 和郎, 井上 聖啓, 柳 務, 高橋 昭, 橋詰 良夫, 小林 直紀, 小野 由子, 柿木 良夫
    1988 年 10 巻 6 号 p. 513-530
    発行日: 1988/12/25
    公開日: 2009/09/03
    ジャーナル フリー
  • 高倉 公朋, 吉田 洋二, 金井 秀樹, 金子 満雄, 福田 利夫, 大根田 玄寿, 斎藤 勇, 塩川 芳昭, 谷口 真, 駒井 則彦, 中 ...
    1988 年 10 巻 6 号 p. 531-546
    発行日: 1988/12/25
    公開日: 2009/09/03
    ジャーナル フリー
  • 1988 年 10 巻 6 号 p. 547-630
    発行日: 1988/12/25
    公開日: 2009/09/03
    ジャーナル フリー
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