Journal of UOEH
Online ISSN : 2187-2864
Print ISSN : 0387-821X
ISSN-L : 0387-821X
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Volume 9, Issue 3
Displaying 1-11 of 11 articles from this issue
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  • Human Monoclonal Cryoimmunoglobulins. Ⅱ. Comparative Studies on the Carbohydrate Contents and Compositions of Cryoglobulins and Myeloma Proteins
    Hiroko SAKAI, Hiroshi NAKAMURA
    Article type: Original
    1987 Volume 9 Issue 3 Pages 267-277
    Published: September 01, 1987
    Released on J-STAGE: April 11, 2017
    DOIhttps://doi.org/10.7888/juoeh.9.267
    JOURNAL FREE ACCESS
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    The carbohydrate contents and compositions of cryoglobulins and myeloma proteins were comparatively investigated by gas-liquid chromatographic and colorimetric analyses. Human monoclonal cryoglobulins, Jir (IgG3κ), Wat (IgG3λ), Fji (IgMκ), and human myeloma proteins, Har (IgGlκ) and Kob (IgAκ) were used for the present experiments. The results obtained were that the carbohydrate contents of Jir and Wat were 2.7 and 4.4% in weight basis; the N-acetyl glucosamine of Wat was almost two times higher than that of Jir and no sialic acid was found in both of these proteins; the total carbohydrate content of Fji was 7.7% and the sialic acid content was 19.3% of the total carbohydrate moiety; the myeloma proteins, Har and Kob, contained 5.3 and 10.4% carbohydrate, respectively, and sialic acid was detectable in these proteins. These results indicate that the carbohydrate contents are variable in each of the proteins, but the relative compositions of monosaccharides in individual samples are nearly the same, except for Kob containing O-glycosidic carbohydrate linkages. In addition, the results showing that sialic acid was detectable in Fji, but not in Jir nor Wat, suggested that the lack of terminal carbohydrate residue was not a common structural feature of cryoglobulins, and was not responsible for the temperature-dependent precipitability of these unusual proteins.
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  • Modification of a Conventional Bicycle Ergometer for Underwater Use
    Yasuhiro SOGABE, Kouichi MONJI, Kiyoharu NAKASHIMA, Fumihiro TAJIMA, J ...
    Article type: Original
    1987 Volume 9 Issue 3 Pages 279-285
    Published: September 01, 1987
    Released on J-STAGE: April 11, 2017
    DOIhttps://doi.org/10.7888/juoeh.9.279
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    With a few simple modifications, a conventional row-bicycle ergometer could be made suitable for underwater use. By attaching three sizes of fins to the pedal cranks of the ergometer, work load in water could be achieved to an oxygen consumption (VO2) level range of 400 to 2000 ml/min. The preferable range of pedaling speeds was 30-40 rpm to maintain a constant speed for a prolonged time. When using three different fins VO2 was found to be: VO2=254.3+4.50n-0.12n²+0.0030n³ for no fins, VO2=250.1+8.30n-0.32n²+0.0062n³ for small fins, VO2=254.0+6.10n-0.24n²+0.0068n³ for medium fins, and VO2=256.4+13.77n-0.72n²+0.0131n³ for large fins, when n is the number of pedaling rate. Major advantages of this modified ergometer for underwater exercise are 1) the modification is simple and the size of the device is small enough to place in a tank of a climatic chamber, 2) the ergometer can be biologically calibrated and used for a wide range of exercise oxygen uptakes, and 3) a subject can exercise in a comfortable upright position.
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  • Variability of Initial Cortical Sensory Evoked Potentials to Posterior Tibial Nerve Stimulation
    Sadatoshi TSUJI, Yoshiyuki MURAI
    Article type: Original
    1987 Volume 9 Issue 3 Pages 287-298
    Published: September 01, 1987
    Released on J-STAGE: April 11, 2017
    DOIhttps://doi.org/10.7888/juoeh.9.287
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    Scalp topographies and distributions of initial cortical positive-negative components of somatosensory evoked potentials (SEPs) to posterior tibial nerve stimulation were studied in 12 normal controls in order to investigate the generator sources of the cortical SEPs. There are three variations in topographies and distributions of early cortical SEPS in normal subjects. In 5 of 12 cases initial cortical positive-negative components were distributed over the centro-parietal areas ipsilateral to the stimulation site or midline parasagittal areas. The origins of these components are speculated to be vertical dipolar generators located at the contralateral interhemispheric fissure. In 5 of 12 cases P37/N36, and N45/P43 showed a phase reversal between the left and right hemispheres and may be generated from horizontal dipoles located at the contralateral interhemispheric fissure. In 2 of 12 cases N36 and P43 were distributed predominantly over the contralateral hemisphere. Oblique dipolar generators located at the contralateral interhemispheric fissure may be oriented prominently to the contralateral hemisphere. Normal variations of initial cortical positive-negative components of SEPs to posterior tibial nerve stimulation should be considered in their clinical applications.
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  • In vitro Effects of Monobactams on Legionella pneumophila
    Shin-ichi YOSHIDA, Yasuo MIZUGUCHI, Yoshihiko NIKAIDO
    Article type: Original
    1987 Volume 9 Issue 3 Pages 299-303
    Published: September 01, 1987
    Released on J-STAGE: April 11, 2017
    DOIhttps://doi.org/10.7888/juoeh.9.299
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    The effects of azthreonam and carumonam against Legionella pneumophila Philadelphia-1 strain in liquid medium and in phagocytic cells were examined. The minimum inhibitory concentration (MIC) of azthreonam for the bacteria was 12.5 μg/ml at a concentration of 1.4X 104 colony forming units (CFU) and 25 μg/ml at a concentration of 1.4X 105 CFU. MIC of carumonam was 25 μg/ml in both concentrations of the bacterial suspension. In guinea pig macrophages, both azthreonam and carumonam at a concentration of 100 μg/ml did not inhibit the multiplication of the bacteria.
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  • Radiological Assessment of Metacarpal Diaphysis by the Microdensitometry Method
    ―In Relation to Physological Aging―
    Shinichi MISHIMA, Katsumi SUZUKI, Nario IHARA
    Article type: Original
    1987 Volume 9 Issue 3 Pages 305-313
    Published: September 01, 1987
    Released on J-STAGE: April 11, 2017
    DOIhttps://doi.org/10.7888/juoeh.9.305
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    In order to clarify the changes brought about in the bone mineral content by physiological aging, a quantitative assessment of bone density seen in X-ray pictures was performed by the microdensitometry method. X-ray pictures were taken of 490 cases (213 males and 277 females), and 768 second metacarpal bones were examined. Indices of the bone mineral content in the male subjects reached their peak in the 4th decade and thereafter gradually decreased with aging. In the female subjects, they reached their peak in the 3rd decade, gradually decreased between the 4th and 5th decade, and showed a marked decrease after the 5th decade. Lateralization of the hand was found. D values of the right hand were always larger than those of the left hand after the first decade, and additionally, △GSmin, △GSmax, ΣGS/D values of the right hand were much more than those of the left hand between the 4th and 5th decade. These results were observed in both sexes. In conclusion, the bone mineral content mainly corresponded to age and sex, but handedness was also regarded as an important factor in influencing the bone mineral content.
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  • A Statistical Study on Anatomical Variation in the Origin of the Japanese Pectoralis Minor Muscle
    Teruyuki HOJO, Tamiji NAKASHIMA, Toshikazu TSURUNO
    Article type: Short Report
    1987 Volume 9 Issue 3 Pages 315-319
    Published: September 01, 1987
    Released on J-STAGE: April 11, 2017
    DOIhttps://doi.org/10.7888/juoeh.9.315
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    The origin of the pectoralis minor muscle of Japanese was studied in the dissection practice for medical students in our school of medicine and the incidence of the Variation of the origin of this muscle was statistically studied and compared with that of American whites and American negroes. The most frequent types in Japanese were type 2-5 (the pectoralis minor muscle arising from the 2nd, 3rd, 4th and 5th ribs) in males and 2-4 in females on both thoracic sides. Type 2-4 in Japanese females was the most frequent among these three ethnological groups.
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  • A Case of Multiple Piloleiomyoma Associated with Submucosal Tumor of the Stomach
    Yoshinori SUENAGA, Osamu YAMAMOTO, Kazukata NISHIO
    Article type: Case Report
    1987 Volume 9 Issue 3 Pages 321-327
    Published: September 01, 1987
    Released on J-STAGE: April 11, 2017
    DOIhttps://doi.org/10.7888/juoeh.9.321
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    A patient with disseminated type multiple piloleiomyoma is reported, He showed multiple painful intradermal nodules on the neck, the back, the chest and the back of the left hand. He had a submucosal tumor of the stomach, which was thought to be a leiomyoma. Multiple piloleiomyoma with other leiomyoma except for uterine myoma is unknown and very rare.
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  • Intractable Diarrhea in Infancy
    ―Whether Infection, Zinc Deficiency, Cholestasis and Hemorrhage are Causes or Results?―
    Minoru YAMAGISHI, Fumiaki HAMAMOTO, Yoshitsugu SHIRAKAWA, Yasusada KAW ...
    Article type: Case Report
    1987 Volume 9 Issue 3 Pages 329-339
    Published: September 01, 1987
    Released on J-STAGE: April 11, 2017
    DOIhttps://doi.org/10.7888/juoeh.9.329
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    Although there has been a marked decrease in the number of infants with intractable diarrhea in Japan, the difficulty in treating it still remains unchanged. Here we report two infants who suffered presumably from "chronic nonspecific enterocolitis" with resistance to the usual treatment. Besides prolonged diarrhea and weight loss, they showed manifestations such as infection, zinc deficiency, cholestasis, abnormal blood coagulation, etc. In this paper, we discuss whether they are causes, effects, results, or coincidences. In spite of the reduction of diarrhea after 3 months of age, both babies are even now being followed up by us because of their still poor weight gain.
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  • A Case of Erythroplakia of the Palate, Tongue and Gingiva
    Katsuaki KABATA, Shouichi NAKAMURA, Kunio IKEMURA, Hiromi TERASHIMA
    Article type: Case Report
    1987 Volume 9 Issue 3 Pages 341-345
    Published: September 01, 1987
    Released on J-STAGE: April 11, 2017
    DOIhttps://doi.org/10.7888/juoeh.9.341
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    A case of a 58-year-old man with erythroplakia, which occurred in the palate, tongue and gingiva, is reported. The histological diagnosis of a biopsy specimen was carcinoma in situ. The patient was treated with irradiation (60Co, 5060 cGy) and chemotherapy (5-FU, arterial infusion, 6400 mg). The erythema completely disappeared following a 6-week therapy, and no atypical cells were histologically recognized. There were no signs suggesting recurrence or metastasis during the follow-up period of 5 months.
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  • 1987 Bioethics Seminar in Fukui
    Masayuki OBAYASHI
    Article type: Report
    1987 Volume 9 Issue 3 Pages 347-350
    Published: September 01, 1987
    Released on J-STAGE: April 11, 2017
    DOIhttps://doi.org/10.7888/juoeh.9.347
    JOURNAL FREE ACCESS
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  • Personal Report on a Visit to Medical Schools in the United States and Italy
    Y. TEZUKA
    Article type: Report
    1987 Volume 9 Issue 3 Pages 351-354
    Published: September 01, 1987
    Released on J-STAGE: April 11, 2017
    DOIhttps://doi.org/10.7888/juoeh.9.351
    JOURNAL FREE ACCESS
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