Japanese Journal of Veterinary Anesthesia & Surgery
Online ISSN : 1349-7669
Print ISSN : 0916-5908
ISSN-L : 0916-5908
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Volume 37, Issue 2
April
Displaying 1-3 of 3 articles from this issue
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REVIEW
BRIEF NOTES
  • A Scleroderma-like Lesion in a Rabbit with Leydig Cell Tumors
    Atsuko KOJIMOTO, Harumichi NAITOH, Saki OZAKI, Shinichi SUZUKI, Naoko ...
    2006 Volume 37 Issue 2 Pages 39-42
    Published: 2006
    Released on J-STAGE: January 30, 2007
    DOIhttps://doi.org/10.2327/jvas.37.39
    JOURNAL FREE ACCESS
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    A diffuse skin thickening lesion with partial nodular formation in the dorsal lumbar area was found in a 6-year-old male rabbit. Skin biopsy of the nodular lesion revealed a thin epidermis and abundant collagen production in the dermis and subcutis with atrophy of appendages. Findings were mostly consistent with human scleroderma. Three months after the initial examination, enlargement of the left testis was noted, and castration was performed. Histopathological examination demonstrated that both testes were Leydig cell tumors. The high serum testosterone level before castration decreased to within a normal range after castration with partial improvement of the skin lesions. These findings suggest that the Leydig cell tumors in this case caused secretion of excessive testosterone, possibly contributing to the formation of a scleroderma-like lesion.
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  • Canine Extraskeletal Osteosarcoma of Rear Limb Originating from Soft Tissue with Metastases in Lung, Abdominal Cavity and Abdominal Wall
    Masako MATSUMURA, Makoto SAKAIDA, Masato YAMADA, Hiroshi AKIYAMA, Hiro ...
    2006 Volume 37 Issue 2 Pages 43-47
    Published: 2006
    Released on J-STAGE: January 30, 2007
    DOIhttps://doi.org/10.2327/jvas.37.43
    JOURNAL FREE ACCESS
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    A female, 8-year-old Labrador Retriever with elevation of the right rear limb was referred to our hospital. We found the mass behind the right knee. Although it was diagnosed as osteosarcoma by Tru-cut core biopsy, morphological abnormality of bone and periosteum commonly seen in the case of skeletal osteosarcoma was not evidenced by X-ray and CT examinations. The amputation of the right pelvic limb by disarticulation of the hip was performed. However, on 147 days after surgery the canine patient died from metastases in lung, abdominal cavity and abdominal wall. The case was definitely diagnosed as extraskeletal osteosarcoma behind right knee originating from soft tissue by X-ray and CT images, postoperative course, biological behavior, macroscopic finding and histopathological examination of the tumor.
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