Feline vaccine-associated sarcoma(FVAS)is a locally aggressive tumor with high rates of local recurrence after incomplete excision. Radical tumor excision with 5 cm lateral margins and 2 fascial planes deep to the tumor was performed in 7 cats(median: 11 years old)with FVAS. Three cats had preoperative radiation treatment(RT), and three cats had local recurrence after previous surgeries. The surgical margins were 5-8 cm from the palpable edges of the tumor, and the suture line in the recurrent cases, or from the RT range. Osteotomy of spinous processes(six cases), partial scapulectomy(two cases), and front limb amputation(one case)were also performed. Complete excision as determined by histologic examination of surgical margins was achieved in five cats, and in the remaining two cats, it was suggestive that the deep surgical margins were not adequate. One cat died of nontumor-related causes within 10 days of surgery. Median survival time of the other six cats was 15. 5 months(3-52 months), and five of them had no evidence of local tumor recurrence at the time of death. Radical excision appeared to be a valuable method of attaining improved outcome with a longer survival time without local recurrence in the treatment of FVAS.

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雑種犬、去勢雄、11歳齢が骨生検による骨肉腫疑いとの事で来院した。左前肢体幹部断脚術を行い、病理検査にて骨肉腫と診断した。術後の補助的化学療法として、カルボプラチンにて治療を行った。初診より1年2 ヵ月目に超音波にて肝臓内側右葉に腫瘤を発見した。肝葉切除術を行い、病理検査にて過形成性結節と診断した。その後、一般状態は良好であったが、初診より2年4 ヵ月目目に超音波検査にて腰椎下動静脈周囲に腫瘤を発見した。Tru-cut 生検にて血管肉腫と診断した。本症例は、骨肉腫の治療中に肝臓腫瘤・血管肉腫に罹患したが、亡くなるまでの2年7 ヵ月間、骨肉腫の再発もなく、非常に良好なQOL を維持することができた。

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