Feline vaccine-associated sarcoma(FVAS)is a locally aggressive tumor with high rates of local recurrence after incomplete excision. Radical tumor excision with 5 cm lateral margins and 2 fascial planes deep to the tumor was performed in 7 cats(median: 11 years old)with FVAS. Three cats had preoperative radiation treatment(RT), and three cats had local recurrence after previous surgeries. The surgical margins were 5-8 cm from the palpable edges of the tumor, and the suture line in the recurrent cases, or from the RT range. Osteotomy of spinous processes(six cases), partial scapulectomy(two cases), and front limb amputation(one case)were also performed. Complete excision as determined by histologic examination of surgical margins was achieved in five cats, and in the remaining two cats, it was suggestive that the deep surgical margins were not adequate. One cat died of nontumor-related causes within 10 days of surgery. Median survival time of the other six cats was 15. 5 months(3-52 months), and five of them had no evidence of local tumor recurrence at the time of death. Radical excision appeared to be a valuable method of attaining improved outcome with a longer survival time without local recurrence in the treatment of FVAS.

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An 11-year-old castrated male dog of mixed breed was referred to the hospital for treatment of suspected osteosarcoma of the left distal radius(Day 1). Limb amputation was performed on Day 4. A diagnosis of osteosarcoma was made histopathologically. The dog was treated with an adjuvant chemotherapy series with carboplatin. On Day 427, abdominal ultrasonography revealed a mass in the medial right hepatic lobe. A partial liver lobectomy was performed, and the lesion was diagnosed as hyperplastic nodules by histopathology. On Day 849, abdominal ultrasonography revealed a mass surrounding the sublumbar arteriovenous area. A Tru-cut biopsy was performed, and histopathology confirmed the diagnosis of hemangiosarcoma. Complete remission of the osteosarcoma was achieved. The patient enjoyed an excellent quality of life for 956 days until death resulting from hemangiosarcoma.

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