Incidence of epithelial tumor developing on the eye-ball, cornea, and conjunctiva has been recognized among cattle in America and it. has been established that many, if not all, cases of benign neoplasm, if left untreated, will undergo a transformation into carcinoma. The affected eye was descrivd as cancer eye. No cancer of the orbital region has not been found in Japan.
The authors encountered a case of malignant neoplasm on the right nictitating membrane of a 9-year-old Holstein cow at the Breeding Stock Farm of the Prefecture of Saga. This report deals with clinical, anatomical, and histological views on this case.
The neoplasm grew on the nictitating membrane at first and then gradually affected the neighboring orbital region. It was metastasized to the right part of the parotid and submaxillary lymph nodes. Histopathological observation disclosed that this neoplasm belonged to glandular-cell carcinoma, or carcinoma simplex, which was different from squamous-cell carcinoma of the typical cancer eye found in America. No bacteria nor virus was isolated from this case in mice and hen's eggs. Cultivation in vitro of this neoplasm was not successful in No.199 media containing 30 per cent bovine serum by the plasma clot method and the trypsindispersed method.

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1) Moniezia expansaの駆虫に当り, カマラの駆虫成績を検討し, 併せてBithionol, Dichlorophenの成績を調査した.
2) カマラの4回にわたる駆虫の成績をみた結果, 完全虫卵陰転は望めず, 駆虫効果にやや不安定性のあるのをみた.
3) Bithionolの投与においては70mg/kg, 50mg/kg 30mg/kgの投薬を行ない, 70mg群では100%, 50mg群では3群中2群が100%, 1群が92%の虫卵陰転率を示した. また30mg群は60%とやや低い結果を得た.
4) Dichlorophenの投与に際しては, 100mg/kg, 150mg/kgの2群に分けて行なった. 100mg群では80%, 150mg群では100%の虫卵陰転率を21日後得た.
5) Bithionol, Dichlorophenの中毒試験においてはいずれも投薬量では軽い下痢, 食欲不振が一部にみられるのみで, いずれも副作用としては問題となり得るものではなかった.
6) Bithionolによる虫体の排虫はMoniezia expansaの場合24時間以内にみられ, 体節のみならず頭部の排泄も確認された. 牛のMoniezia benedeniにおいてもBithionol30～10mg/kgの各量を与え副作用を認めず虫卵陰転をみ, 排虫も1例確認した.

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Recently soft-icecream has come rapidly into popular taste, manufactured in small facilities such as kitchens of coffee-shops. A survey was conducted to find out any influence of the actual situation of manufacturing upon the sanitary conditions of finished products, chiefly from a bacteriological point of view.
In the survey, samples were collected during the manufacturing process of soft-icecream and examined for the presence of bacteria, especially Escherichia coli. For this purpose, plants of 8 makers were selected at random. There the capacity of the manufacturing machine, the process of manufacturing, tools and utensils used in the process, raw material, and finished products were investigated. When the raw material and finished product were compared, the latter was markedly, contaminated probably due to imperfect disinfection of the machinery.
It has been reported that fish and other seafood were incriminated for about 60 per cent of the outbreaks of food poisoning all over the countly. Also in Gifu Prefecture there were many outbreaks of food poisoning the cause of which was the ingestion of fish and its processed products. Fish is indispensable for the Japanese as food. Although it is eaten mostly raw, it is cooked and handled directly with bare hands in almost all cases. Such being the case, a survey was conducted to elucidate the actual state of contamination of sashimi, or sliced raw fish, and sushi, or fancy raw-fish relish. As a result, all the samples of sliced raw fish gave positive coliform-bacteria tests.

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Some investigations on the relationship between the possession of antibodies (complement-fixing (c. f.) and neutralizing antibodies) in pre-inoculation serum and susceptibility for virus inoculation, were carried out with 2-to 4-month-old puppies. The following results were obtained.
1.(a) After the virus inoculation, neutralizing antibody was demonstrated more than c. f. antibody in mild or symptomatic cases.
(b) Severe and fetal cases were found mostly, among animals without both antibodies, although a few animals survived without them.
So, it seems that there are some relations between the neutralizing antibody and the susceptibility.
2. After the virus was inoculated in to puppies intravenously, both antibodies were not demonstrated in the course of disease in fatal acute cases, but in survived cases, development of these antibodies was recognized 7 days after inoculation.
3. In guinea pigs inoculated with the virus intraperitoneally, remarkable development of both antibodies was observed about 2 weeks after inoculation.
From these observations, it is shown that a guinea pig can be employed, instead of a dog, in the assay for vaccine and anti-serum of infectious canine hepatitis. That a dog is considered as only susceptible animal, constitutes

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Studies on crystallization and cytological obser-vation of nasal-mucus smear were performed on 260 cases of improved Nipponese black cows and Holstein-Friesian cows which were bred in the suburbs of Tottori from May, 1955, to December, 1956.
The data obtained can be summarized as follows
1) The crystallization phenomen on of the nasal-mucus smear treated with silver nitrate could be found with the same crystallization pattern observed in the cervical mucus.
2) The crystallization pattern of the nasal mucus was classified into ten types.
3) The crystallization phenomen on of the nasal mucus presented an indisputed cyclic variation.
4) The cellular content observed was composed mainly of epithelial cells, thin neutrophile leucocytes, lymphocytes, eosinophile leucocytes, and monocytes. In the estrus these cells made their appearance in a larger number in the cellular content than in the other stages of the sexual cycle.

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