Two dairy cows were affected with general amyloidosis, showing emaciation, anemia, edema, cessation of milk secretion, and absence of estrus. Hepatomegaly of milk secretion, and absence of estrus. Hepatomegaly was confirmed by biopsy in one of them. No pictures were present to indicate the regeneration of erythrocytes. Remarkable proteinuria was characteristic of both cows.
Hypoproteinemia was observed. Paperelectrophoretic analysis revealed a decrease of albumin and an increase of α- and β-globulin, particularly γ-globulin. It also proved that not only albumin but also globulin appeared in the urine.
In the etiological consideration, it was presumed that these cases might be related to Johne's disease.

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In the past four years, some cases of toxoplasmosis were detected from among those slaughtered at the Yawatahama Meat Packing Center in Ehime Prefecture, Shikoku. The etiologic organism was harbored in many organs, causing infiltrations of lymphocytes, lymphoid cells, and macrophages. It was difficult to find out any chronic case of this disease.

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A female bovine fetus with many deformities on the head and face was obtained at the Hanyu Slaughter house. It was 77 cm in crown-rump length and 31kg in body weight. Dissection of it gave the following findings.
(1) The deformities observed were cyclopia, agenesis of nose, formation of a proboscis, astomia, synotia, agnathia, anencephalus, and hydrocephalus.(2) The single median orbit contained an eyeball of normal size, but neither optic nerve nor retina was seen.(3) The proboscis, formed under the orbit, was covered with skin which had hairs outside and outer loose and inner fatty connective tissues inside. It contained no nasal tube.(4) In spite of astomia, there was a small oral cavity, which contained a rudimentary tongue, and a pharyngeal cavity, which was divided from the oral cavity by lateral folds.(5) The right and left ears were displaced downwards. Each of them had an external auditory canal and a fused tympanic cavity. A wide eustachian tube opened to this cavity from the dorsal wall of the pharynx.(6) No cerebrum nor greater part of the diencephalon was seen. The other parts of the brain-stem, except a smaller part of the diencephalon and the cerebellum, appeared to be well-formed. A wide opening of the sylvian aqueduct was blown out into a thin-walled hydrocephalic sac containing abundant cerebrospinal liquid.(7) The cranial bones, especially some anterior ones, were very abnormal in composition and shape due to the deformities described above. No mandible was seen.(8) Much liquor was contained in the stomach.

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香川県において, ホルスタインフリーシアン系雌牛の先天性ポルフィリン症2例を発見した.
その歯は不潔なピンク色で, 発育が遅れ痩削し, 尿は淡赤褐色であったが皮膚に病変はなかった. 高温な夏の間は著しく貧血し, 赤血球はほとんど異常なものであった, しかし, 気温の低降と日照量の漸減に伴って, ポルフィリンの排出は減少して正常な赤血球が出現し, 一般状態が好転した. 本症牛の状態は, 季節と密接な関係があるようである.
剖検において, 赤褐色一チョコレート色の骨質と骨髄腔の拡大による骨質の減少, 骨髄の軟化, 脾臓の腫大を認めた. また, 骨は紫外線の照射によって鮮かな赤色の螢光を発現した.
本症牛は, その系統の調査から米国より輸入した種有牛に由来することが考えられた.

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都市近郊酪農の通弊として, 高蛋白飼料給与があげられる. この結果としてもたらされるウシの生理状態に及ぼすひずみがいかなるものであるか, 一般酪農, 専業酪農の両形態を県畜産試験場と4季別に対比し血中成分の生化学的追究をこころみ, 飼養上の教訓を得たいと考えた. この結果つぎの知見を得た.
1. 飼料給与状況
DM: A群は4季を通じて不足, B群は秋春に不足, C群は冬に不足の傾向をみとめた.
DCP: A群, C群で冬に適量であったほか, いずれの群も全般に過給であった.
TDN: A群で夏秋に過給であったほか, 全般に適量給与がなされていた.
DCP/TDN: A群では各季とも適であったのに対し, B, C群では冬をのぞき常時過高を示した.
2. 血中成分
NPN: A群では冬のほかおおむね正常値の範囲内にあったが, B, C群では季を問わず常に高値であった.
UN: A群では冬にやや高値であったほか正常範囲にあり, B群では季を問わず常に高く, C群では冬のほか常に高値であった.
UN/NPN: A群では夏に低値, 冬に高値を示したが他の季には正常範囲にあった. これに対しB, C群では季を問わず常時高値を示した.
T. ch: A群では年間を通じて正常範囲にあり, B群では夏以外, C群では常時過高を示した.
Tp: A, B群とも常時正常範囲にあり, C群では秋春に高値を示した.
A/G: A群では常に正常, B群では夏に低いほか正常, C群では常時低値を示した.
BS: とくべつな傾向はみとめられなかった.

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