Four dairy cows were affected with amyloidosis. They manifested persistent serous diarrhea, anorexia, edema, and emaciation. No treatment was successful and a poor prognosis made at 18-57 days of illness. Biochemically, hypoproteinemia was serious, albumin and γ-globulin decreased, and α-globulin increased. Besides, α2-macroglobulin and β-lipoprotein increased and IgG decreased remarkably. Proteinuria was intense. Pathologically, amyloid nephrosis was severe. In almost all the organs amyloid deposition was noticed in small blood vessels and their perivascular connective tissue. Edematous changes were distinct in the digestive tract. Amyloidosis may have been induced subsequently to chronic infections, which were chronic mastitis in all the cows and hepatic abscess in one cow.
Rectal examination was performed on a total of 72 sows since 1968. The ovary was touched in 68 sows. Polycystic ovary was found in 51 sows. PMS had no curative effect on these sows. This examination was applied effectively over a period of 30 days to 7 weeks after parturition to detect any disorder in the ovary due to disturbances in the internal secretion.
Over a period from June 29 to July 20, 1977, Salmonella arizonae infection broke out in turkey poults imported from farms W and R in the United States. Most deaths occurred during the first 3 weeks. The total fatality was 48.5% during this period. Poults were affected with diarrhea, nervous symptoms, and blindness. S. arizonae 18: Z4, Z32 (Arizona 7: 1, 7, 8) was found in autopsy materials from 50 poults. S. arizonae strains isolated were susceptible to chloramphenicol, tetracycline, and kanamycin.
A male poodle 8 years old weighing 15.5 kg was affected with intense ascites and microfilariae in the blood, manifesting anorexia and coughing. No symptomatic treatment was effective and subjected to euthanasia. Autopsy revealed tumors from rice grain to soybean in size were scattered all over the liver and tumors 1.0-1.5 cm in diameter in the spleen. Histological examination revealed enlarged blood vessels irregular in caliber filled with fluid or coagulated blood in the liver. These vessels were surrounded by connective tissue, including argentaffine fibers, which was distinguished clearly from the hepatic tissue. Hepatic cells suffered from intense atrophy, degeneration, and necrosis. Similar changes of hemangioma were seen in the spleen. The present case was diagnosed as multiple spongy hemangioma.