Swine abortion was frequently seen on a farm in 1990. Four of the fetuses which were aborted at 95-102 days of gestation showed varying degrees of petechial and ecchymotic hemorrhages on their skin with subcutaneous edema. Macroscopically, the fetuses had free reddish fluid in the thoracal and peritoneal cavities, hepatomegaly, with a mottled reddish-yellow color, linear hemorrhaging in the heart and enlargement of the lymph nodes. However, six of the fetuses at 72-95days of gestation did not show any specific changes. Microscopically, nonsuppurative choriomeningitis, degenerated and necrotic hepatocytes, epi-or endocarditis, angitis were observed. Chlamydial inclusion bodies were confirmed in the cytoplasm of infiltrated monocytes, hepatocytes and trophoblastic cells by immunohistochemical staining. In addition,
Chlamydia psittaci (
C. psittaci) was isolated from 2 fetuses with severe lesions. Serological and bacteriological examinations did not reveal any evidence suggestive of abortion in swine due to Aujeszky's disease virus, Japanese encephalitis virus, porcine parvovirus, Getah virus,
Toxoplasma gondii and Escherichia coli. On the other hand, Chlamydial antibodies were detected among many sows and fattening pigs. This is the first report in the literature of C. psittaci-caused swine abortion in Japan.
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