Three cases of canine keratomycosis were reported. All the cases showed photophobia, epiphora and ulcers with grayish opacity but no hyphemia, hypopyon, anterior synechia, nor corneal vascularization. In case 1, a third eyelid flap was placed over the cornea, followed by topical administration of antibiotic and atropine ophthalmic ointments, however the corneal lesion became worse. Direct smear and culture of the corneal exudate detected
Aspergillus fumigatus as the possible pathogenic agent. Therefore, topical nystatin and amphotericin B therapy was instituted, but no improvement was noted. In cases 2 and 3, the fungal elements were detected by the direct examination and
Candida albicans was isolated by culture of the corneal scrapings. These 2 cases were recovered without scar formation by treating topically with pimaricin, FAD and 1% sodium-chondroitinsulfate-sol for a month or with pimaricin alone for two weeks.
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