In 5 canine cases of idiopathic thrombocytopenic purpura (ITP) with more than 200×103/μ
l platelets after steroid or other immunosuppressive therapy, clinical findings, hemostatic screening test and platelet aggregation to adenosine diphosphate (ADP) were evaluated. While all the 5 cases showed no abnormal findings in hemostatic screening test, subcutaneous bleeding, ecchymoses and delayed hemostasis were continuously recognized in 3 of 5 cases after blood sampling, and defects of platelet aggregation against to ADP were detected in 4 cases, suggesting that bleeding tendency might be due to platelet dysfunction in some canine cases of ITP.
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