A male Japanese Black calf, five month old, was presented with history of chronic diarrhea. The calf was necropsied because the diarrhea was continued in spite of symptomatic treatments. Microscopically, chronic necrotizing granulomatous gastroenteritis with zygomycetes and systemic candidiasis were observed. Immunohistochemically, the fungi were positive for anti-Rhizomucor antibody in the abomasum and for anti-Candidaantibody in the kidney.Absidia corymbiferaandCandida tropicaliswere isolated from small intestine and kidney by fungal cultures, respectively. This report describes the dual mycosis caused byAbsidia corymbiferaandCandida tropicalisin a Japanese Black calf.
The clinical utility of the urine albumin/creatinine ratio (UAC) in cats with chronic renal failure was studied using a simplified UAC analyzer. The measurement results for diluted feline albumin standard solution showed linearity, with the need of a conversion formula (y=1.28x+1.04) and the ability to measure the feline urine albumin concentration. In cats with chronic renal failure, the UAC changed parallel with the urine protein/creatinine ratio (UPC), and the Log UAC and Log UPC were significantly correlated (r=0.795, P<0.01). The Log UAC and the plasma creatinine concentration were not significantly correlated. In cats with chronic renal failure, the UAC was thought to have the same clinical utility as the UPC, and to be a clinical indicator for renal function.
Serum iron (Fe), zinc (Zn), copper (Cu) and selenium (Se) concentrations and whole blood manganese (Mn) concentration were measured in dogs given 40μg/kg of lipopolysaccharide (LPS) from E. coli O127, B-8, intravenously. Serum Fe and Zn decreased significantly at one day after LPS injection (day 1) and Fe increased from day 3 as a rebound reaction. Copper increased from day 2 and Se decreased dramatically at days 1 and 2. In contrast, no significant changes were found in six control dogs given physiological saline. No significant change was found in blood Mn concentration, irrespective of the LPS injection. To evaluate the effect of glucocorticoid on moderating the LPS-induced changes above, three dogs were pretreated with dexamethazone 2mg/kg injection intramuscularly two hours before LPS injection. The changes of serum trace elements concentrations in the dogs given LPS described above were significantly moderated by the pretreatment.
A four-year-old male, crossbred rabbit was referred for diagnosis of a mass on the right mandible. An excisional biopsy sample of the mass was diagnosed as a chondorosarcoma. Seventeen days after the biopsy, a recurrence of the tumor was confirmed and the mass was surgically resected by a partial hemimandibulectomy. The rabbit recovered uneventfully from surgery and had remained clinically normal. On re-examination, 57 days postoperatively, the recurrence of the tumor was confirmed and was surgically resected with the remaining right caudal mandible. Sixty three days after surgery, the rabbit was euthanized because of dyspnea. Necropsy revealed pulmonary metastasis and tracheal stenosis by a abscess formation.
The effects of five commercial disinfectants on inactivating avian influenza viruses were investigated. All disinfectants used in this study were found to be sufficient to inactivate avian influenza viruses, irrespective of their pathogenicity or haemagglutinin and neuraminidase subtypes and even with repeated freeze -thawing of diluted disinfectants. However, the effectiveness of disinfectants decreased at low reaction temperatures and with contamination of the mixture with fecal material. It was concluded that the disinfectants used in this study were effective in inactivating avian influenza viruses given the appropriate dilution of disinfectants, higher reaction temperatures and the removal of organic matter at use.