A 15-year-old female appaloosa with an adherence between the upper and lower eyelids of the right eye was presented to our hospital. Ultrasonographically, a massive lesion with unhomogenous echogenicity had infiltrated into the bulbar conjunctiva and the following whole corpus vitreum, and was rich in blood vessels. The histopathological examination revealed a squamous cell carcinoma on the conjunctiva, and it was decided to conduct a transpalpebral eye enucleation. The diagnosis of the removed globe was ocular squamous cell carcinoma with deep intraorbital invasion, but the optical nerve was not affected.
A ten-year-old male Edward's pheasant (Lophura edwardsi) was found dead in a zoo. At necropsy, an oval-shaped mass (4.5× 4 × 4cm) was located in the digestive tract, involving the lower small intestine and the upper large intestine. The mass was creamy white in color. Histologically, the neoplastic tissues were detected mainly in the lamina propria of the affected intestine. Single or clumps of tumor cells were detected in substantial amounts of mucus, forming mucous lakes. Most of the mucous lakes were surrounded by thin connective tissues. As the mucus was positively stained with Alcian blue (pH1.0, pH2.5), toluidine blue, periodic acid Schiff (PAS) and Mucicarmine, the mucus was considered to be acid mucin of epithelial origin. Ultrastructurally, the plasma membranes of the tumor cells were connected with desmosomes. The case was diagnosed as intestinal mucinous adenocarcinoma. It is the first report of an intestinal mucinous adenocarcinoma in a bird.
A 3-year-old female miniature dachshund presented with acute astasia for which magnetic resonance imaging
(MRI) was performed. On neurological examination, the postural response and spinal reflex in the four
limbs were abnormal. MRI revealed a mass in the C4-5 dorsal spinal region with hypointensity on T2-weighted
images and isointensity on T1-weighted images. After gadolinium enhancement, the mass was enhanced
in the shape of a ring. Moreover, the mass extended to the surface of the body. Surgical resection of the mass
was performed and its histological diagnosis was a dermoid sinus. From these findings, this case was diagnosed
as a type Ⅳ dermoid sinus. This is the first report of a type Ⅳ dermoid sinus in a miniature dachshund.
Gastric carcinoids were observed in three adult female bearded dragons (Pogona vitticeps). Macroscopically, large and transmural tumors were seen in the stomach of all cases, and Case 3 had hepatic metastasis. Microscopically, in all cases, infiltrative tumor cells proliferated without capsulation and formed nests and ribbon-like rows of cells. Pseudorosette formation was observed in Case 2. Some tumor cells were poorly adhesive, having scant cytoplasm and small round pyknotic nuclei. The other tumor cells had large, spindle shaped and bright nuclei. Immunohistochemically, the tumor cells were positive for chromogranin A and synaptophysin in all cases. Only Case 1 expressed cytokeratin. In electron microscopy, neuroendocrine granules averaging 220 nm in diameter were seen in the cytoplasm of the tumor cells in Case 3.
A nine-year-old female Pomeranian presented with a one-year history of intermittent episodes of coughing. Clinical signs included severe dyspnea and cyanosis. Breath sounds were loud only around the caudal lobe of the lung. The clinical signs and a radiological examination of the thorax indicated that the dog had pulmonary emphysema. Computed tomography of the thorax revealed a large rounded area of radiolucency surrounded by a thin radiopaque structure. We resected several resectable vesicular structures and sutured other unresectable vesicular structures. Histological examination revealed multiple cysts lined by bronchial epithelia,with some cartilage and connective tissues. The dog recovered well after surgery and survived with no signs of respiratory illness.
The liver and kidney samples collected from 101 Japanese black bears were assayed by ICP-MS to determine arsenic, cadmium, chromium, mercury and lead concentrations. No bears had arsenic and chromium concentrations exceeding 0.2 and 1.0 mg/kg, respectively. Mean cadmium concentration was 0.9 mg/kg for the liver and 15 mg/kg for the kidney. Mercury concentration was below 0.2 mg/kg in most of the bears, but one bear had 1.05 mg/kg mercury in his liver. The mean lead concentration was 0.37 mg/kg both in the liver and kidney, but two bears had lead concentrations in the lever exceeding 2 mg/kg. The present results are consistent with our previous report, which suggested the lead contamination of Japanese black bears. A new finding is that cadmium and lead concentrations are significantly higher in the Kitaou local population than in the Kitakami-sanchi local population.