To investigate drug sensitivity and estimate the risk of drug resistance for public health, the authors examined the drug susceptibilities of
Escherichia coli and
Klebsiella spp., derived from bovine mastitis that occurred in the Ishikari area of Hokkaido from June to September 2006. Eighteen antimicrobial agents used in veterinary and human medicine were selected. A total of 106
E. coli and 34
Klebsiella spp. were tested, and 29.2% of strains of
E. coli and 91.2% of
Klebsiella spp. showed antimicrobial resistance. However, the resistance rates of
E. coli were lower than the indicator bacteria of food-producing animals. All of them were sensitive to the second choice antibiotics widely used with animals and humans. Therefore, it is considered that
E. coli and
Klebsiella spp. originating from bovine mastitis in the area may have a low direct influence on human health.
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