A pathologic examination was conducted on a 15-week-old wasting pig at a farm in Saitama Prefecture, Japan. At necropsy, multiple white nodules (0.2-1.0 cm in diameter) were detected on the surface of the liver and spleen, serosa of jejunum, ileum and colon, pulmonary pleura, epicardium and mesentery. Histologically, the white nodules were abscesses with gram-positive bacteria, and were surrounded by thick connective tissues. Immunohistochemically,
Arcanobacterium pyogenes antigen corresponded to the organisms in the abscess. Short bacilli were isolated from the liver, spleen, kidney, heart, lung, and pleural fluid. The isolates were confirmed as
A. pyogenes by biochemical analyses. Comparative 16S rRNA gene sequencing analysis of the isolates also revealed that they were likely the same species of
A. pyogenes. The present case was diagnosed as swine multiple suppurative serositis caused by
A. pyogenes.
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