Three goat kids aged 24 days to three months old at two goat-breeding farms in Okinawa Prefecture, Japan were from April to May 2012 examined for the diagnosis of respiration and arthritic diseases. Polyarthritis, pleuropneumonia and keratitis were observed via necropsy. The major histopathological lesions shown were as follows - case 1: infiltration of macrophages in the alveoli with thick alveolar septa; case 2: suppurative fibrinous arthritis in the carpal joint and tarsal joint; case 3: suppurative bronchopneumonia in the lung lobes and purulent keratitis. Mycoplasma spp. were isolated from all three of the lungs, several joints and synovial fluids in the kids. The mycoplasma isolates were identified as Mycoplasma mycoides subspecies capri (Mmc) by the biological properties, PCR and PCR-RFLP analysis. Immunohistochemically, Mmc antigens were detected in the joint cavities, bronchi, alveoli and cornea. The cases were diagnosed as polyarthritis, pyogenic bronchopneumonia and purulent keratitis by Mmc infections.
A 1-day-old male Japanese Black calf displayed the sudden onset of clinical symptoms of recumbency and opisthotonus. A cerebral contusion was suspected, and vitamin B1, antibiotics, and nonsteroidal anti-inflammatory drugs were administered. The calf apparently recovered except for ataxia. Hypermetria of the limbs, a wide stance, and a progressive decline in menace reaction was seen when the case became 8 months old. There were no macroscopic findings in the brain. From histopathologic findings the case was diagnosed as cerebellar cortical degeneration, including the marked degeneration and loss of Purkinje cells and granule cells.
A castrated 13-year-old male papillon had difficulty defecating. Echography revealed the presence of a huge mass in the pelvic cavity. Based on the needle biopsy findings and clinical history, the mass was suspected to be a seminoma that had metastasized to a medial iliac lymph node. Because the tumor was close to several large blood vessels and urethral tubes, it was considered to be difficult to resect. We performed radiation therapy first (4 MV X-ray, 5.4 Gy/fraction, 3 times/week, total 37.8 Gy). As a result, the tumor decreased to 47% of its primary size on the last day of radiation therapy, and to 29% after another 14 days. Fourteen days after the last radiation therapy, we surgically resected the remaining tumor. The canine has had a benign course. Preoperative irradiation can be very effective for canine seminoma metastasized to a medial iliac lymph node, which is difficult to resect.