Orthodichlorobenzene cresol complex formulation (trade name: Tanabezole, Osaka Kasei Co., Ltd., Osaka) has been recognized not only for killing larva of flies but also for its antimicrobial and anti-parasitic properties. In this study, we investigated the anti-avian influenza virus properties of this agent in ovo. It showed strong anti-avian influenza virus properties. When this agent was diluted at 1 : 100 to 200 and put into contact with avian influenza virus for 10 minutes at room temperature (37 ºC), no surviving virus was detected. Although its anti-viral properties weakened somewhat at 4 ºC, this agent showed strong anti-avian influenza virus properties when it was put into contact with the virus for 60 minutes at same temperature. The presence of organic matter in virus fluid did not affect the anti-avian influenza virus properties. It was concluded that this agent is a useful disinfectant in the poultry industry.
Feline polycystic kidney disease, an autosomal dominant genetic disease (fADPKD), has clinical presentations similar to humans. Clinicopathological features of fADPKD were described associated with hepatic cysts in three cats. In addition, histological examination of cystic livers and analysis of the cystic fluid were performed. All three cases were male Persian and Persian breed-related cats. Localized multilocular hepatic cysts in two cats and a large solitary hepatic cyst in one cat were observed. Grossly visible multilocular hepatic cysts were mostly located in the peripheral portions of hepatic lobules. Microscopic cysts were also observed in the parenchyma of the liver. These hepatic cysts were lined by a single layer of low cuboidal epithelial cells. The hepatic cystic fluid had higher potassium and urea concentrations, but similar sodium, chloride, and creatinine concentrations when compared to serum. No blood test findings suggested decreased liver function.