Nineteen untreated hyperthyroid patients were divided into 4 groups. The control group was treated by methimazole and propranolol and the other groups by methimazole, propranolol and herbal medicine (
Shakanzoto, Saikokarkotsuboreito or Keishikaryukotsuboreito extracts) together. In
Shakanzoto-treated group the reduction rate of serum thyroxine in the early stage of treatment and the reduction rate of serum triiodothyronine in the whole period of treatment were significantly higher than the control. These observations suggest that treatment with
Shakanzoto can be effective in hyperthyroidism by reducing the increased serum thyroid hormone.
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