Kampo Medicine
Online ISSN : 1882-756X
Print ISSN : 0287-4857
ISSN-L : 0287-4857
Volume 45, Issue 1
Displaying 1-14 of 14 articles from this issue
  • 1994 Volume 45 Issue 1 Pages 1-36
    Published: July 20, 1994
    Released on J-STAGE: March 12, 2010
    JOURNAL FREE ACCESS
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  • 1994 Volume 45 Issue 1 Pages 37-95
    Published: July 20, 1994
    Released on J-STAGE: March 12, 2010
    JOURNAL FREE ACCESS
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  • Tadanobu ITO, Shigeo MURAI, Hiroko SAITO, Maki ITO, Junichi ODASHIMA, ...
    1994 Volume 45 Issue 1 Pages 97-106
    Published: July 20, 1994
    Released on J-STAGE: March 12, 2010
    JOURNAL FREE ACCESS
    We studied the effect of Saiko-ka-ryukotsu-borei-to (crude extract powder for research purposes) on central monoamine-related substances in mice. The formulation was given in a dose of 50mg/kg or 400mg/kg and was administered once or repeatedly (twice a day for seven days). The brain was removed and segmented in the conventional method. The monoamine-related substances were measured by a method using HPLC-ECD. The main results were as follows. The single or repeated administration of 50mg/kg increased DOPAC and HVA contents in the cerebral cortex. In the hypothalamus, the single 50mg/kg treatment decreased NE, and the repeated 50mg/kg treatment decreased NE but increased DOPA. In the corpus striatum, the single 50mg/kg administration increased DA, DOPAC, HVA, and 5-HIAA while the repeated administration increased NE and MHPG as well. In this region, the single 400mg/kg treatment increased NE and 5-HIAA, and the repeated treatment increased NE. In the hyppocampus, the repeated 50mg/kg treatment increased MHPG, and the repeated 400mg/kg treatment decreased HVA. These results indicate that the effect of this formulation on murine brain monoamines is greater at 50mg/kg than at 400mg/kg and that the effect varies among the regions of the brain.
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  • Analysis of the relationship between improvement of subjective symptom and Kampo diagnosis
    Masahiro UMINO, Masanori NAGAO, Shozo MUROGA
    1994 Volume 45 Issue 1 Pages 107-113
    Published: July 20, 1994
    Released on J-STAGE: March 12, 2010
    JOURNAL FREE ACCESS
    The effect of Byakko-ka Ninjin-to-on xerostomia in elderly patients and the relationship between the improvement of subjective symptoms and kampo diagnosis were studied. Xerostomia improved in 60 percent of 30 patients treated with Byakko-ka-Ninjin-to. There were significantly more patients who were less advanced in years and with a good constitution in the effective group than in the non-effective group.
    Although the occurrence of appetiteoss was significantly higher in the non-effective group, there was no significant difference between the groups with respect to the occurence of constipation, diarrhoea, boborysmus, upper abdominal bloatedness or cold constitution. No significant differences between the groups were shown in the occurrence of oral kampo diagnosis such as bitter taste in the mouth, thirst, stickiness in the mouth, and mucosal dryness.
    From these results it is concluded that Byakko-ka-Ninjin-to is effective for elderly patients who are not too advanced in year and who have a good constitution and (sthenia).
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  • Quantification of Pulse Waveform with a Four-Factor Concentrated Constant Circuit Model
    Hitoshi ISHIYAMA, Hiroshi KASAHARA, Kazuo KODAMA, Fenghao XU, Kazuhiko ...
    1994 Volume 45 Issue 1 Pages 115-121
    Published: July 20, 1994
    Released on J-STAGE: March 12, 2010
    JOURNAL FREE ACCESS
    A total of 120 measurements were made for pulse waveform of the radial artery in 73 male subjects in their twenties to forties. We then calculated the parameters in the four-factor concentrated constant circuit model using the method we had developed. From the waveform of the radial artery, we extracted forms equivalent to those referred to as normal, slippery, and string-like pulses according to the pulse-wave models described in the literature. By comparing these parameters, we could show quantitatively the differences in waveforms and related diagnoses of pulses.
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  • Hiroki MIZOBE, Makoto ARAI, Hiroshi SATO, Fumihiko SIROTA
    1994 Volume 45 Issue 1 Pages 123-127
    Published: July 20, 1994
    Released on J-STAGE: March 12, 2010
    JOURNAL FREE ACCESS
    A 82-year-old patient with congestive heart failure visited our hospital complaining of dyspnea and orthopnea. Initially, treatment was given based on the western medicine. She responded very well to a diuretic, with her congestive heart failure improving in a relatively short period of time. However, she could not adhere to the restriction of water intake she was supposed to follow was hospitalized repeatedly. While she was in hospital, just rest and water restriction alone improved dyspnea. Although she was discharged from hospital and was given increased doses of a diuretic and a vasodilator, congestive heart failure recurred. Since there was moderate discomfort of the hypochondrium and disturbance of the body's fluid metabolism, we added Sairei-to to her treatment. Six weeks later, the discomfort of the hypochondrium cleared. Her appetite started to improve and she had less severe dryness of the mouth. she was therefore gradually able to follow the water restriction and has not had recurrence of heart failure since then. Although Moku-boi-to is frequently used in the treatment of heart failure, it is assumed that a formulation with a diuretic action such as Gorei-san was effective because heart failure represents a disturbance of the body's fluid metabolism.
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  • Yutaka NOZAKI
    1994 Volume 45 Issue 1 Pages 129-135
    Published: July 20, 1994
    Released on J-STAGE: March 12, 2010
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    I report a case of nephrotic syndrome which responded to Saiko-shimotsu-to with Uzu and Chorei-to without Kasseki. About eight months ago before visiting clinic, a 56-year-old male patient underwent a regular health examination, which took place at the Agricultural Cooperative Association. He was found to have proteinuria. He was diagnosed as having nephrotic syndrome and was treated accordingly. However, he did not respond to various types of treatment, and his conditions aggravated. Severe edema, proteinuria, and hypoproteinemia were noted. When Saiko-shimotsuto was given, he improved a little. When the above formulation was given, these signs were cleared completely. When we reduced the doses of Uzu and Akyo, these signs aggravated, indicating that these ingredients play an important role in improving such signs. Although it has occasionally been reported that Saiko-shimotsu-to is used for gastric ulcer, there is no published record that it has been used for nephrotic syndrome. This case is unique in that the use of Uzu for the syndrome of a Yin disease was effective for proteinuria and hypoproteinemia and that Saiko-shimotsu-to was effective.
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  • Kuniya KOIZUMI, Toshihiko HANAWA, Syogo ISHINO, Yasuo OTSUKA, Hiroshi ...
    1994 Volume 45 Issue 1 Pages 137-140
    Published: July 20, 1994
    Released on J-STAGE: March 12, 2010
    JOURNAL FREE ACCESS
    Neuralgia due to tabes dorsalis is refractory to treatment. We report a case which responded to Kagawa-gedoku-zai-kamiho. A 55-year-old female patients started having persistent systemic pain, particularly frequently in both of her lower extremities. It did not improve, and the diagnosis was made as tabes dorsalis at Fukushima Medical College Hospital. After antisyphilitic therapy, she underwent acupuncture and treatment with various drugs for systemic pain. However, the analgesic effect of this treatment gradually diminished, and she was referred to our institute (Department of Kampo Medicine). Based on her medical history and systemic conditions, we prescribed the above formulation. The analgesic effect of a nonsteroidal anti-inflammatory drug (suppositories) gradually increased. When pain in the legs later became more severe, Bushi and Daio were given in increased doses, which relieved the pain completely and enabled the patient to stop the suppositories. In January, 1993, pain developed again in the arm. The doses of Bushi and Daio were increased, which gradually reduced the pain. Kampo medicine seems to offer promising treatment for syphilis after antisyphilitic therapy.
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  • Kiyoko HATTORI
    1994 Volume 45 Issue 1 Pages 141-146
    Published: July 20, 1994
    Released on J-STAGE: March 12, 2010
    JOURNAL FREE ACCESS
    Hitherto, very few clinical trials have been conducted to study anosmia. I studied two cases with anosmia where Koso-san used according to Kamopo Diagnosis was effective.
    Case 1: A 42-year-old female patient had anosmia after rhinitis caused by cold was cured. The problem persisted, and the otorhinolaryngologist diagnosed it as a refractory case. A fourmonth treatment did not work, and she visited my office for Kampo medicine.
    Case 2: A 75-year-old male patient had realized since two or three years previously that his sense of smell had declined. When he could not smell spilt perfume, he knew he had anosmia. He was greatly shocked and visited my office.
    Koso-san was given to these two patients in three divided doses a day (7.5g daily) before meals and subsequently gave very good results. I rediscovered the importance of therapy given according to Kampo Diagnosis, which is fundamental to Kampo therapy.
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  • Hiroshi KAMIYA
    1994 Volume 45 Issue 1 Pages 147-150
    Published: July 20, 1994
    Released on J-STAGE: March 12, 2010
    JOURNAL FREE ACCESS
    A suitable effect was seen in 13 cases (65%), and a slight effect was seen in 4 cases (20%). In 3 cases (15%), Rikko-san proved to be ineffective.
    Mild pain after tooth extraction became no pain. In 5 cases of moderate pain after tooth extraction, 4 cases were reduced to mild pain, but in 1 case there was no pain relief. There was no reduction in severe pain after tooth extraction. No subjective side-effects were observed.
    Although Rikko-san may be effective for mild pain after easy tooth extraction, it appears not to be sufficiently effective in cases of moderate or sever pain after difficult tooth extraction.
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  • Shigeyuki TAKAMORI, Takashi ANDO
    1994 Volume 45 Issue 1 Pages 151-157
    Published: July 20, 1994
    Released on J-STAGE: March 12, 2010
    JOURNAL FREE ACCESS
    A 48% incidence of muscle cramps was found in 150 patients with liver cirrhosis. A 76.7% incidence of muscle cramps was found in patients with decompensated liver cirrhosis, which was statistically higher than a 36.4% incidence in patients with compensated liver cirrhosis.
    In order to evaluate the effect of Hachimi-jio-gan on the treatment of muscle cramps in cirrhotic patients, 5g or 7.5g of Hachimi-jio-gan was administered orally to 31 cirrhotic patients (15 patients in the compensated stage and 16 patients in the decompensated stage), who had suffered from muscle cramps at a frequency of more than once a week. The frequency of muscle cramps was found to have decreased in all patients and to have completely disappeared in 19 patients (61.3% of 31 patients) following administration of Hachimi-jio-gan orally for 4 weeks.
    The vibration perception threshold (VPT) was examined in 5 cirrhotic patients. The VPT improved in all patients in proportion to the decrease in the frequency of muscle cramps following administration of Hachimi-jio-gan orally.
    The effect of Hachimi-jio-gan was compared to the effect of Gorei-san ane Shakuyaku-Kanzo-to on muscle cramps in 11 cirrhotic patients. The effective rates were 100%, 36.4% and 54.5% respectively. Judging from these results, Hachimi-jio-gan can be considered more effective in giving relief from muscle cramps. Hachimi-jio-gan was also effective in giving relief from muscle cramps in 6 cirrhotic patients in which Mecobalamin had no effect.
    These results suggest that Hachimi-jio-gan is a useful drug for the treatment of muscle cramps in patients with liver cirrhosis.
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  • Kiichiro TSUTANI, Takao NAMIKI, Shinichi MURAMATSU
    1994 Volume 45 Issue 1 Pages 159-164
    Published: July 20, 1994
    Released on J-STAGE: March 12, 2010
    JOURNAL FREE ACCESS
    For its 1993 activity, the Data base Subcommittee, Editorial Committee, the Japan Society for Oriental Medicine (JSOM) made a survey of: (1) the starting year of publication; (2) the starting year of indexing; and (3) the number of articles in the 54 serials indexed in JMEDICINE. (The names, pablication Codes, etc are reported in the Nihon Toyo Igaku Zasshi, 45: 571-575, 1993, as the 1992 activity of the Subcommittee's A general picture of the period covered and the number of articles indexed in JMEDICINE were revealed in the survey. In view of the recent improvement in the accessibility to JMEDICINE, further use of it in research and clinical work is recommended.
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  • 1994 Volume 45 Issue 1 Pages 165-179
    Published: July 20, 1994
    Released on J-STAGE: March 12, 2010
    JOURNAL FREE ACCESS
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  • [in Japanese], [in Japanese]
    1994 Volume 45 Issue 1 Pages 185
    Published: July 20, 1994
    Released on J-STAGE: March 12, 2010
    JOURNAL FREE ACCESS
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