Kampo Medicine
Online ISSN : 1882-756X
Print ISSN : 0287-4857
ISSN-L : 0287-4857
Volume 52, Issue 4-5
Displaying 1-7 of 7 articles from this issue
  • Jong-Chol CYONG
    2002 Volume 52 Issue 4-5 Pages 387-395
    Published: January 20, 2002
    Released on J-STAGE: March 12, 2010
    JOURNAL FREE ACCESS
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  • Akihiro IGATA
    2002 Volume 52 Issue 4-5 Pages 397-408
    Published: January 20, 2002
    Released on J-STAGE: March 12, 2010
    JOURNAL FREE ACCESS
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  • 2002 Volume 52 Issue 4-5 Pages 409-481
    Published: January 20, 2002
    Released on J-STAGE: March 12, 2010
    JOURNAL FREE ACCESS
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  • Tsutomu YAMADA, Toshinori OINUMA, Makoto YOSHIMURA
    2002 Volume 52 Issue 4-5 Pages 483-492
    Published: January 20, 2002
    Released on J-STAGE: March 12, 2010
    JOURNAL FREE ACCESS
    We studied the effect of Kampo for the size-limitation of myocardial infarct with morphometrical analysis, utilizing total of 19 male swine. A hand made metal-coil (2×1mm) was inserted in the left anterior descending coronary artery (LAD) of swine with catheterization, in order to induce acute myocardial infarction (AMI). After occurrence of AMI, the swine were divided into two groups, experimental group: Saiko-ka-ryukotsu-borei-to (n=10) and control (n=9). This Kampo formula (0.66/kg/day) was administered via stomach tubes for 4 weeks. The control group received basal rations alone. After serial cross sections of heart, total infarct areas were weighed.
    An infarct weight to heart weight of the experimental group (2.9±1.6%, n=10) was significantly decreased than that of the control group (8.2±4.8%, n=9). The infarct weight to left ventricular weight of the experimental group (4.9±2.6%) was significantly decreased than that of the control group (13.4±8.0%). Thus the infarct size of the experimental group was significantly smaller than that of the control. The histological character of the infarct in the control was numerous inflammatory cell infiltration and foci of fresh coagulate necrosis in the border zone, while the infarct of the experimental group was apparent in the border zone with marked fibrosis and few inflammatory cells. Angiogenesis in both the infarct and border zone was marked in the experimental group than in the control. We summarize that this Kampo formula inhibits size development of AMI in animal model.
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  • Herbological Study of Collection Season
    Mitsue MATSUMURA, Masayuki MIKAGE
    2002 Volume 52 Issue 4-5 Pages 493-499
    Published: January 20, 2002
    Released on J-STAGE: March 12, 2010
    JOURNAL FREE ACCESS
    Ge-gen, a Chinese crude drug derived from the root of Pueraria lobata Ohwi of the family Leguminosae, is collected in the winter nowadays both in China and in Japan. However, in the old descriptions of materia medica written in ancient China, it was said that the proper collection season was May or in the early summer on Chinese calendar. Present herbological study resulted that the collection season had been changed in the Yuan or Ming dynasty in China, mainly because of the confusion with eating Ge-gen, which was collected in the winter. The Ge-gen collected in the early summer should be dispensed in the prescriptions written in the old medical books such as Shang-han-lun and Jin-kui-yao-lue.
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  • Akito HISANAGA, Takashi ITOH, Atsushi NIIZAWA, Koichi YOKOYAMA, Toshia ...
    2002 Volume 52 Issue 4-5 Pages 501-505
    Published: January 20, 2002
    Released on J-STAGE: March 12, 2010
    JOURNAL FREE ACCESS
    We report a case of obstructive sleep apnea syndrome effectively treated with Hange-koboku-to. A 32-year-old male suffered from globus syndrome (globus hystericus), excessive daytime sleepiness and snoring. He underwent uvulopalatopharyngoplasty at the age of 27, but the symptoms did not improve after surgery. Nocturnal polysomnography, performed before administration of Hange-koboku-to, confirmed the diagnosis of obstructive sleep apnea syndrome. After 1-month-administration of Hange-koboku-to extract (Tsumura Co. Ltd., 7.5g/day), his complaints almost disappeared. After 5-month-administration of Hange-koboku-to, nocturnal polysomnography was performed again. As a result, the apnea index fell from 19.2 events/hour to 10.3 events/hour, and the apnea-hypopnea index also fell from 19.2 events/hour to 12.8 events/hour. He was not obese (body mass index: 23.0kg/m2), and no significant body weight change was observed after administration. No adverse effect was observed. To our knowledge, there is no other report on the treatment of sleep-related breathing disorders with Hange-koboku-to. We presume that Hange-koboku-to may decrease the upper airway resistance, especially at the lower part of the upper airway.
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  • Withdrawal from Steroid and Effect of Sekko
    Jiro FUJIWARA, Midori FUKUDA, Yoshiko INOUE, Yoshiko SAITO
    2002 Volume 52 Issue 4-5 Pages 507-514
    Published: January 20, 2002
    Released on J-STAGE: March 12, 2010
    JOURNAL FREE ACCESS
    Treating atopic dermatitis patients, who have used steroid, only through Chinese herb medication, it often happens that extract medicine doesn't work well and infusion one is needed.
    We treat with Seiun-haidoku-in-kagen “Ekisin-ittoku” and its amount, to stop using steroid, often exceeds as twice or three times much as ordinary use. Especially Sekko needs large quantities, 40-100g a day for adults to get out of steroid.
    In early treatments, some patients couldn't stop applying steroid because of insufficient increase of Sekko, but after increasing its amount until it have effects, they all have got out of steroid.
    It is effective to take herb-medicated bath and some original ointment at the same time. We report on the case in which one can withdraw from steroid by these treatments.
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