Kampo Medicine
Online ISSN : 1882-756X
Print ISSN : 0287-4857
ISSN-L : 0287-4857
Volume 74, Issue 4
Displaying 1-10 of 10 articles from this issue
Clinical Reports
  • Keita MIYANISHI, Michihiko HIRATA, Kazuhiro ORIBE
    Article type: Clinical Reports
    2023 Volume 74 Issue 4 Pages 307-313
    Published: 2023
    Released on J-STAGE: June 23, 2024
    JOURNAL FREE ACCESS

    We herein report the successful treatment of three elderly patients in an orthopedic clinic who were successfully treated using the Kampo formula of rokumigan and shimotsuto. The first patient was a 69-year-old woman with rheumatoid arthritis who complained of subjective coldness in her feet. The second patient was a 79-year-old man with lumbar spinal stenosis who presented with pain and paresthesia of his lower extremities, which aggravated by walking. The third patient was an 80-year-old man who complained of ambulatory pain in the body trunk and lower limbs, which had started more than ten years previously. The symptoms of these three patients resolved after the initiation of treatment with rokumigan and shimotsuto (a Japanese herbal medicine), which was given based on dry mouth, frequent urination, flushed face, insomnia, and skin drying. Tokaku Wada (a Kampo doctor in the Edo period) stated in the classical text “Shosohoikai” that the conditions of kekkyo (blood deficiency) and jinkyo (kidney deficiency) often exist together. We concluded that rokumigan and shimotsuto may be considered for patients presenting with the Kampo concept of kekkyo and jinkyo, even if they have different diagnoses under Western medicine.

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  • Yae YOSHIDA, Kayoko NAKAMOTO
    Article type: Clinical Reports
    2023 Volume 74 Issue 4 Pages 314-320
    Published: 2023
    Released on J-STAGE: June 23, 2024
    JOURNAL FREE ACCESS

    Herein, we report kyukikyogaito treatment that was effective for repeated hemoptysis due to pulmonary endometriosis. A 27-year-old Japanese woman visited our hospital because of repeated hemoptysis associated with menstruations. Computed tomography (CT) on one day of hemoptysis revealed ground-glass pattern in the left lower lobe, and later we confirmed bleeding from left B6 bronchus by bronchoscopy. We diagnosed her as having pulmonary endometriosis clinically. She had repeated hemoptysis every month for 3 years with a moderate amount of bleeding. At the age of 30, she showed frequent hemoptysis for several days in February in 20XX. We conducted oriental medical examination, and diagnosed blood deficiency and deficiency cold pattern as the main pathological conditions. We administered kyukikyogaito for the duration of each menstruation. She took kyukikyogaito for the first 3 days of her menstruation in March, and for the 5 days from 2 days before her menstruation in April. As a result, she had a small amount of hemoptysis only once in 2 months. She stopped taking kyukikyogaito from May, and her hemoptysis resolved. In Western medicine, the therapeutics of pulmonary endometriosis are endocrinotherapy and surgery. It was suggested that kyukikyogaito is effective for pulmonary endometriosis with imperfection of throughfare and conception vessels pattern, and deficiency cold pattern.

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  • Masafumi MURAI, Takafumi YATSU, Kanako MAKI, Noriko KOBAYASHI
    Article type: Clinical Reports
    2023 Volume 74 Issue 4 Pages 321-325
    Published: 2023
    Released on J-STAGE: June 23, 2024
    JOURNAL FREE ACCESS

    A 20-year-old woman had a tendency of belching from a young age. She began to realize that she might have excessive belching compared to other people for the past two years. She was prescribed some medicines to improve gastrointestinal function by some physicians, but her symptoms did not resolve. Aerophagia was suspected as forceful belching tends to occur soon after eating or drinking. Incidentally, ihon is a condition in which one vomits food half a day after the ingestion due to the malfunction of the digestive system. I considered her symptoms as ihon and prescribed bukuryotakushato, and her symptoms improved. This case report indicated that ihon could be defined as a symptom of forceful regurgitation of food or air, regardless of the timing after meals.

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  • Keizo TOKUMO, Yuko NEZU
    Article type: Clinical Reports
    2023 Volume 74 Issue 4 Pages 326-330
    Published: 2023
    Released on J-STAGE: June 23, 2024
    JOURNAL FREE ACCESS

    We report a case of cancerous ascites which did not respond to goreisan but respond to the combination of saireito and eppikajutsuto, resulting in the reduction of ascites and QOL improvement. A 73-year-old woman with abdominal distention was referred to our department for suspicion of ovarian cancer after visiting an nearby internal medicine clinic in August, X. She had advanced ovarian cancer and underwent laparotomy. Postoperative chemotherapy was performed, but the cancer recurred one year and three months later. The treatment for the recurrence was ineffective, and cell-free and concentrated ascites reinfusion therapy (CART) was performed for cancerous ascites as a palliative therapy from August X+3. Goreisan was administered to decrease ascites, but it was ineffective. Then, saireito and eppikajutsuto were administered, which decreased ascites in spite of aggravation of the disseminated peritoneal lesions. The interval of CART was prolonged from two weeks to four weeks and more. Her quality of life (QOL) also improved.

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  • Shinichi YAMAMOTO, Ayako OSAFUNE, Akira MATSUI, Kuniaki TANAKA
    Article type: Clinical Reports
    2023 Volume 74 Issue 4 Pages 331-337
    Published: 2023
    Released on J-STAGE: June 23, 2024
    JOURNAL FREE ACCESS

    We report a case of drug-induced cystitis caused by the administration of two different Kampo medicines containing Scutellariae radix. The patient was prescribed bofutsushosan for weight gain at the age of 55. She visited her primary care physician approximately one month later for micturition pain and other symptoms, and was prescribed antibacterial agents based on a diagnosis of bacterial cystitis. The patient’s symptoms persisted even after she was treated for one month ; therefore, she was referred to the urology department of a general hospital. All medicines including Kampo medicines were discontinued ; her subjective symptoms and urinary findings improved within 2 weeks. Her symptoms of cystitis flared up after a few days of re-administration of bofutsushosan. Four months later, she developed cystitis-like symptoms again after using nyoshinsan for menopausal symptoms. Based on the aforementioned clinical observations, she was diagnosed with drug-induced cystitis due to bofutsushosan and nyoshinsan administration. The components of these two Kampo medicines and past history of Kampo medicine use were reviewed and Scutellariae radix was considered to be the causative agent. Drug-induced cystitis caused by herbal medicines generally takes a long time to develop, and symptoms resolve within a relatively short period following discontinuation of the causative agent. Several reports in the literature implicate Scutellariae radix as the etiological agent in such cases. We believe that it is necessary to pay close attention to the risk of cystitis in patients receiving long-term Kampo therapy.

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  • Hiroki INOUE, Ayako YAGUCHI, Naoyuki HARADA, Keiko NAKAO, Ryo YOSHINAG ...
    Article type: Clinical Reports
    2023 Volume 74 Issue 4 Pages 338-341
    Published: 2023
    Released on J-STAGE: June 23, 2024
    JOURNAL FREE ACCESS

    The persistent genital arousal disorder (PGAD) is a condition in which intense abnormal sensations and pain appear in the genital area without sexual stimulation. Here, we report two cases of PGAD successfully treated with tokishigyakukagoshuyushokyoto. Since dysfunction of nerves and blood vessels is thought to be involved in the cause of PGAD, we believed that tokishigyakukagoshuyushokyoto, which improves ischemia of the pelvic cavity organs, would be a good indication for this treatment. Tokishigyakukagoshuyushokyoto should be considered especially when tenderness in the inguinal region is observed.

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  • Akiko SHIRAI, Keiko OGAWA
    Article type: Clinical Reports
    2023 Volume 74 Issue 4 Pages 342-347
    Published: 2023
    Released on J-STAGE: June 23, 2024
    JOURNAL FREE ACCESS

    Ménière’s Disease is an unexplained inner ear lymphedema disease. We report a case of atypical Ménière’s Disease with frequent urination in which choreitogoshimotsuto (CRTST) was effective. A 47-year-old woman had repeated bilateral tinnitus and hearing loss for the past 3 years, and was diagnosed with an atypical case of Ménière’s Disease at a local otolaryngologist. She continued oral administration of isosorbide, but repeated exacerbations and remissions. Given the pathology of fluid retention, blood deficiency, static blood, and yin deficiency, we prescribed her CRTST referring to the symptom of frequent urination. The symptoms of frequent urination and tinnitus subsequently improved and CRTST was naturally discontinued after 1 year and 3 months. CRTST has the effects of fluid regulation, heat clearance, nourishment of yin, tonifying blood, and resolving blood stasis. Goreisan and Saireito are generally used for Ménière’s Disease because inner ear lymphedema is regarded as fluid retention. This case shows that CRTST can be an effective option for treatment of Ménière’s Disease caused by pathological conditions such as fluid retention, blood deficiency, static blood, and yin deficiency.

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  • Yoshito HAMANAMI, Junsuke ARIMITSU, Keiko OGAWA-OCHIAI, Yoshinobu MATS ...
    Article type: Clinical Reports
    2023 Volume 74 Issue 4 Pages 348-352
    Published: 2023
    Released on J-STAGE: June 23, 2024
    JOURNAL FREE ACCESS

    We have experienced a case of response to keishikajutsubuto for stump pain after both femoral amputations. There are few reports on the use of Kampo medicines for stump pain after amputation. In this case, the critical lower-limb ischemia that led to the amputation was due to severe stenosis and occlusion caused by arteriosclerosis in both limbs. From the perspective of Kampo medicine, ischemia is considered to have cold and blood status as a result of deficiency and stagnation of yang qi due to circulatory failure. In this case, we regarded blood stasis as a secondary product of ischemia, and we mainly considered a prescription to remove cold and bring yang qi to the eliminative organs, which was effective for the pain. For stump pain after amputation that is poorly responded to general analgesics, the combination of keishikajutsubuto is expected to provide rapid analgesic effect, suggesting that it is useful for pain control.

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  • ―Consideration for Maximizing the Usefulness of Treatment with Yojinkodakuto―
    Hirofumi HIRANA, Kazuhiko SHIMIZU, Akihiro FUTAMURA, Kazuyuki HIRATANI ...
    Article type: Clinical Reports
    2023 Volume 74 Issue 4 Pages 353-364
    Published: 2023
    Released on J-STAGE: June 23, 2024
    JOURNAL FREE ACCESS

    We report a case of 2X-year-old man with G4 chronic kidney disease (CKD G4). He had a decline in estimated glomerular filtration rate (eGFR) after the initiation of BEP (cisplatin, etoposide, bleomycin) therapy followed by VelP (ifosfamide, cisplatin, vinblastine) therapy for mixed germ cell testicular tumor. The patient’s eGFR did not recover during 59 months after chemotherapy, but showed a tendency to improve after treatment with yojinkodakuto. Yojinkodakuto was prepared by the IPCD (immersing powdered crude drugs) method. The IPCD method was adopted to ensure convenience and good quality prescription herbal medicines. Although eGFR fluctuated after yojinkodakuto treatment, at 3 years, serum creatinine (sCr) and eGFR progressed well, with sCr reducing from 3.98 mg/dL at initiation to 2.6 mg/dL and eGFR increasing from 16 mL/min/1.73 m2 to 25.4 mL/min/1.73 m2. In addition, a long-term eGFR plot analysis confirmed the 3-year improvement trend.

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Explanation
  • Naoko OSADA, Takeshi SUGAWARA
    Article type: Explanation
    2023 Volume 74 Issue 4 Pages 365-379
    Published: 2023
    Released on J-STAGE: June 23, 2024
    JOURNAL FREE ACCESS

    The two books, “Hyakuchin-ikkan” and “Dr. Toukaku’s Houyo and it’s hearing”, have long been believed to have written by Toukaku Wada (A famous doctor in the Edo period). However, their medical recipes and the way they perceive disease were extremely different from those in Toukaku’s other publications. Interestingly, however, they closely resemble the contents of “Houyogei” written by Keiri Arimochi (also a famous doctor in Edo period). In this study, therefore, we set out to resolve this conundrum. We researched other books of Toukaku more deeply, but we were unable to find any commonalities between the two books in question and the other books of Toukaku. On the other hand, We found the name Dr. Kyourin multiple times in “Hyakuchin-ikkan,” and we posited that Kyourin was the real author of that book. Moreover, while we found Kyourin to be an alias of Keiri, there was no evidence of Toukaku being the Dr. Kyourin. In addition, we confirmed that “Toukaku’s Houyo” is the predecessor and model for Keiri’s one. We thus determined that both books, “Hyakuchin-ikkan” and “Toukaku’s Houyo and it’s hearing,” were based on the medical experiences of Keiri Arimochi and not those of Toukaku Wada.

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