The author studied on the culture properties and drug resistance of Ps. aeruginosa isolated from the chronic otitis media during the past four years, and a summary of the results is shown below: 1. Ps. aeruginosa were isolated in the percentage of 9.0-13.3 from the chronic otitis media, and 25.8% of them were found together with staphylococci. 2. It was generally observed that staphylococci or Candida in the focus werereplaced by. Ps. aeruginosa. 3. The isolation of non-pigment strains showed an increasing tendency. 4. The resistance of Ps. aeruginosa against CL. PLB and GM showe an increasing tendency. 5. The minimum inhibitory concentration of CL and PLB against most strains of Ps. aeruginosa was below 3.12 mcg/ml, and that of GM was 1.56 mcg/ml, but that of CB-PC was above 6.25 mcg/ml.
Patient: 39 year-old male. Personal and family history: Nothing particular. On the night of 10th January 1970 he was taken ill with high fever, headache and vomiting. On 17th January, the seventh day after the onset, he was admitted to the hospital. The clinical findings at the time of admission were as follows. Temperature 39.6°C, he was in dreamy state and agony. Nuchal rigidity and Kernig's sign was positive. Gram positive short rod was isolated from the cerebrospinal fluid. Its morphological findings and biochemical properties are identical with those of Listeria monocytogenes, i. e. it caused monocytosis in rabbit by its i. v. inoculation and conjunctivitis by its eye smering. Serologically, i. e. by cross agglutination test and absorption test, this strain was identified as Listeria monocytogenes type 1 and named as “Yorimitsu strain” by the authors. The epidemiology of this case has not been clear yet. By adding this case, the total number of human listeriosis cases in this country counts 41. The summary of these 41 cases is indicated in Table 6-9.