1) Between January and October in 1972, the survey of 140 patients with respiratory infection revealed significant number of microorganisms in sputum. Haemophilus influenzae forms 29.3 per cent of those microorganisms.
2) Serotypes of 100 Haemophilus influenzae strains isolated from sputa were as follows: nontypable 62, type-d 23, type-a 6, type-b 2, type-c 1, mixed type 6.
3) 120 patients with Haemophilus influenzae respiratory infection were made up of acute infection of 9.2 per cent, chronic infection 67.5 per cent and the others 23.3 per cent.
4) Haemophilus influenzae respiratory infection is ecologically classifiable into 3 types, I to III. Type-I is most frequent, and type-III is least.
5) The mechanisms of induction and colonization of Haemophilus influenzae into respiratory tract were devided into 5 types.
i) secondary infection following viral infection
ii) acute exacervation type
iii) canal infection type
iv) drug induced type
v) antibiotic error
6) We devised quantitative analysis of Growth Factor of Haemophilus influenzae in sputum.
7) Serum precipitins against Haemophilus influenzae were highly detected in patients with chronic respiratory infection.
8) Susceptibility of Haemophilus influenzae to 19 antibiotics was examined. Ampicillin was most effective in them.
9) Electron microscopic studies revealed that the antibiotic mechanism of Ampicillin to Haemophilus influenzae mainly depends on the effect to cell wall, and protoplasts of them were produced.
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