From the laboratory and clinical investigations on T-1220, the following results were obtained.
1) Antibacterial activity of T-1220 was measured by the plate dilution method on 83 strains isolated from pathological materials in our clinic. The peak of MIC was 0.78μg/ml with sensitive
Staphylococcus aureus (22strains). The antibacterial activity of T-1220 against
Proteus species and
Pseudomonas species was better than ABPC and CBPC.
2) T-1220 was prescribed clinically in 10 cases of ear, nose, throat and larynx infections, and effective rate was 66.7%.
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