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Volume 57, Issue 4
Displaying 1-6 of 6 articles from this issue
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Hikaru TANAKA, Hiroko NAKAZATO, Hironobu KOGA, Koichi WATANABE, Naomi ...1983 Volume 57 Issue 4 Pages 289-296
Published: April 20, 1983
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSAn indirect fluorescent antibody (IFA) test was used to establish the background prevalence of antibody to Legionella spp. in a single serum specimens from healthy Japanese. These have been compared with antibody levels obtained from stocked sera and patient's sera with pneumonia or febrile illness.
We used two groups of polyvalent antigens of Legionella spp., which included: group 1-L. pneumophila, serogroup 1 to 4, and group 2-L. pneumophila, serogroup 5 to 6, L. micdadei, L. bozemanii, L. dumoffii and L. longbeachae.
In this paper the higher titer from group 1 and 2 was used as the titer of Legionella group. All the high titers that we observed (≥1:64) with the polyvalent antigens, was confirmed with the use of monovalent antigens.
Of 527 healthy persons, 237 (45%) had titers of <4:13 (2.5%) had titers ≥1:64 (12 had a titer of 1:64 and 1 a titer of 1: 128). The proportion of antibody did not vary with sex, however, the higher age groups demonstrated greater level.
The overall prevalence of seropositibity (reciprocal titer, ≥64) in 527 healthy persons, 125 patients with pneumonia or febrile illness and 755 stocked sera was in each 2.5%, 4.8% and 1.3% respectively.
The observed titer of 1: 128, corresponded to L. pneumophila, serogroup 1.
No serum had an antibody titer ≥1:256 in all of the 1407 sera examined.View full abstractDownload PDF (855K) -
Jyuji HOSHINO, Hiroko YOKOTA, Makoto SAITO, Nagayo SHIMIZU, Masachika ...1983 Volume 57 Issue 4 Pages 297-302
Published: April 20, 1983
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSClinical studies on Pipemidic acid (PPA) for bacillary dysentery and its carrier were carried out with the following results.
1) PPA was effective for improving of clinical symptoms and eradication of Shigella.
2) Combined administration of PPA and KM may be more effective than PPA only. But, more experience is needed.
3) Exception of one case of skin eruption, no remarkable side-effect was seen in both groups.
Then, PPA will be applied to bacillary dysentery safely and effectively.View full abstractDownload PDF (475K) -
Makoto SAITO, Isao TOMIZAWA, Kazumi KONISHI, Yoshihiko TAKIZAWA, Yoshi ...1983 Volume 57 Issue 4 Pages 303-317
Published: April 20, 1983
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSThe efficacy of Pipemidic acid (PPA), a new synthetic antibacterial agent, was compared with that of Kanamycin (KM) for the treatment of bacillary dysentery patients or carriers by a double blind method. PPA and KM were administered in a dosage of 2.0g/day for a period of 5 days respectively. Of 211 cases studied, efficacy was evaluated in 139 cases; 73 received PPA and 66 KM. There was no significant difference between the two groups in terms of the background factors.
The results obtained were as follows:
1) According to the clinical efficacy, the ratio of “excellent plus good” was 86.3% with PPA group and 78.5% with KM group. There was no significant difference between the two groups, while PPA group was found to be significantly superior in patients groups, with PPA group being 92.5% and with KM group being 72.5%.
2) With respect to the efficacy for symptoms as evaluated by the effect on defervascence, disappearance of bloody stool, decrease of number of defecation and improvement in stool character, PPA group was found to be significantly superior to KM group in all of these symptoms but stool character.
3) Effect on bacterial discharge, PPA group was found to be significantly superior to KM group, with PPA group being 95.9% and with KM group being 77.3%.
4) Clinical symptoms as side effects were observed 2 cases in PPA group and 3 cases in KM group.
5) On the MIC of shigellae isolated from clinical cases, peak levels of PPA group was 1.56μg/ml and KM group was 6.25μg/ml.View full abstractDownload PDF (1290K) -
Yoshiko INAZUMI, Hiroshi OGURO, Eichin BOKU, Shinya IKEDA, Teiko MURAI ...1983 Volume 57 Issue 4 Pages 318-332
Published: April 20, 1983
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSThe total of 15 times throat cultures and 3 times blooding were performed on 12, 988 healthy school children, 97% of the registered, at two primary school at Nikko City, Tochigi Prefecture, for the period of January 1973 to October 1977. The isolated Beta-streptococci were grouped and T-typed serologically and Anti-streptolysin 0 titer was examined. Some scarlet fever and acute glomerulonephritis patients were observed during the corse of investigation.
The results obtained were as follows;
1) Positive rate of beta streptococci carriers was higher in winter time and lower in summer time, 42.6% at the highest and 10.9% at the lowest. The isolated beta streptococci belonged to group A as much 82.0%, B 4.0%, C 3.5% and G 10.0%.
2) Most prevalent T-type of group A belonged T-1, T-4 and T-12, showing the same T-type pattern as that reported on the patients in the whole country.
3) Distribution of T-type of isolated strains was different in each school and class, suggesting the important role of the class room.
4) Prevalent pattern of T-12 during the corse of investigation were different from those of T-1 and T-4.
5) The carrier rate of scarlet fever and acute glomerulonephritis patients was rather low compared to the non-attacked children.
6) Carrier state of the same T-type does not necessary stimulate the elevation of ASO titer, but new carrier state or change in T-type of carrying streptococci served to-stimulate ASO.
7) It seems that the prevalent T-type among healthy carrier in non-epidemic period would not be the prevalent type in the following epidemic period.View full abstractDownload PDF (1515K) -
Rintaro INOUE, Yoshihiko MITSUTAKE, Nagaomi TAKAHASHI, Reiichiro HIDAK ...1983 Volume 57 Issue 4 Pages 333-338
Published: April 20, 1983
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSA case of perimyocarditis and glomerulonephritis associated with mycoplasma pneumoniae pneumonia was reported. A 32-year-old man was admitted to the hospital because of left precordial chest pain and dyspnea. Physical examination revealed friction rub at left sternal border in 4th intercostal space. ECG showed ST elevation in lead 1, 2, aVL, aVF and chest leads. Chest X-ray showed homogenous infiltration of right lower lung field without changes in cardiac silhouette.
Laboratory investigation revealed W. B. C. 12, 200 with 16% stabs and 70% segs, urinalysis 80mg/dl protein and microscopic hematuria R. B. C., 3-4/HPF. A kidney biopsy revealed mesangial cell proliferation. EM studies demonstrated dense deposits along the endothelial cell. CF antibody titer to mycoplasma pneumoniae increased to 1: 512 two weeks after admission. The patient made complete recovery in eight weeks after treatment with erythromycin, josamycin and minocycline.View full abstractDownload PDF (4517K) -
1983 Volume 57 Issue 4 Pages 371-373
Published: April 20, 1983
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSDownload PDF (303K)
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