All issues
Volume 58, Issue 1
Displaying 1-9 of 9 articles from this issue
- |<
- <
- 1
- >
- >|
-
Kazuo TABUKI, Tadafumi NISHIMURA, Toshio TAKASHIMA1984 Volume 58 Issue 1 Pages 1-8
Published: January 20, 1984
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSThe serologic and clinical studies of infection due to Chlamydia psittaci were studied in children with respiratory tract infection for three years from October 1979 to December 1981.
Pneumonia was found in 107 of the 430 patients with lower respiratory tract infection; chlamydial infection was in 21 of these 107 patients.
Mycoplasma pneumonia was found in 12 of the 21 patients with chlamydial infection.
Clinically, the duration of cough and fever did not differ significantly between the chlamydial infection group and the mycoplasma pneumonia group, however the duration of pneumonia shadow and cough was longer in the mixed infection group than in the chlamydial infection group.
Patients with positive chlamydial antibodies were frequently exposed to pet birds and others.View full abstractDownload PDF (960K) -
Kei NUMAZAKI, Shunzo CHIBA, Shuji NAKATA, Tatsuru YAMANAKA, Tooru NAKA ...1984 Volume 58 Issue 1 Pages 9-14
Published: January 20, 1984
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSRecently, Chlamydia trachomatis (C. trachomatis) has been recognized as a common genital tract pathogen causing nongonococcal urethritis, pelvic inflammation and purulent cervitis. C. trachomatis infection in neonates is aquired perinatally, and major clinical consequence of exposure to C. trachomatis for infants are the occurrence of inclusion conjunctivitis and afebrile pneumonia.
Although clinically suspected cases of C. trachomatis infection are often seen in Japan, little is known about the pathogenic role of C. trachomatis in this country as well as in many other Asian countries. Therefore we attempted to isolate C. trachomatis from Japanese infants with pneumonia and described a preliminary report of success in isolation of this agent elesewhere.
In this study, IgG antibody to C. trachomatis was determined in 1005 Japanese adults and children with microimmunofluorescence (micro-IF) using reticulate bodies (RB) as single antigen. Formalin-fixed RB of C. trachomatis L2 (434) strain were used as an antigen in micro-IF test. Of 183 healthy adults, 44 (24.0%) had titers of 1: 10 or more. Among 565 infants and children, a progressive increase in seropositivity was observed except 6- to 8-year-olds: 9.2% infants under 1 year-old, 22.5% for 1- to 5-year-olds, 14.8% for 6- to 8-year-olds, and 28.9% for 9- to 15-year-olds.
These data suggest that C. trachomatis infection occurrs commonly in Japanese aults and children.View full abstractDownload PDF (5104K) -
Masanori AIHARA, Yoshikazu HASHIMOTO, Tamaki NAKAMURA, Masako MATSUMOT ...1984 Volume 58 Issue 1 Pages 15-22
Published: January 20, 1984
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSAs a rapid method of diagnosis of bacterial infections, co-agglutination (CoA), latex agglutination (LA) and counter immunoelectrophoresis (CIE) were tested in order to detect the capsul antigens of pneumococcus and H.influenzae in specimens from patients.
A comparative study with these three serological tests showed that CoA test was four to thirty-two times sensitive as LA and CIE.
From 136 specimens of cerebrospinal fluid (CSF), two cases of meningitidis purulenta demonstrated H.influenzae and pneumococcus respectively by both serological and conventional methods. In the case of pneumococcal meningitidis, the antigen was detected by CoA and LA during two days after chemotherapy commenced, although negative results were obtained by the conventional method.
From 97 sputum specimens, capsul antigens were detected by CoA and LA in 16 specimens; especially CoA tests were positive for H.influenzae type b in two cases, for H. influenzae type a, c-f in seven cases and for pneumococcal antigens in 11 cases, whereas nine antigen were detected by LA test.
Positive CIE test was seen in only two clinical specimens; CSF from H. influenzae type b meningitis and sputum from pneumococcal pneumoniae.
CoA test was found to be a useful tool for a rapid diagnosis of these bacterial infections as compared with other serological tests such as LA and CIE for detection of pneumococcus and H.influenzae antigens on clinical specimens.View full abstractDownload PDF (933K) -
Yasuko KOMAGATA, Akira GHODA1984 Volume 58 Issue 1 Pages 23-28
Published: January 20, 1984
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSWe have reported that IgE antibody production was enhanced by sensitization with vibrio cholerae whole cell or a component of vibrio cholerae IF52. We designed to find out factors which suppress the IgE antibody production. Mice were sensitized intraperitoneally with IF30, IF52 or vibrio cells before or after the immunization. IgE antibody production by DNP-vibrio cholerae was suppressed when sensitized intraperitoneally with IF30, but IgM antibody production was suppressed by sensitization with IF30 before immunization. Vibriocidal antibody production was enhanced by sensitization with IF30. IgE antibody production by DNP-ovalbumin was suppressed by sensitization of IF30, but IgM antibody production was enhanced and IgE antibody production was not affected. Non-specific IgE antibody production was enhanced by sensitization with IF52.
Another study was designed to check the combined effect of oral and intraperitoneal sensitizations. Mice were first sensitized orally with IF30 or killed vibrios and were sensitized intraperitoneally with either IF30 or killed vibrios, then mice were immunized with DNP-vibrios. This sensitization method suppressed IgE antibody production stronger than one intraperitoneal sensitization with IF30, enhanced IgM antibody production, did not affect IgG antibody production and enhanced vibriocidal antibody production.
Therefore, combination of the oral and systemic sensitization will be the best method for the induction of the protective immunity for cholera.View full abstractDownload PDF (726K) -
Naoki KATO, Yasuhisa ITOH, Takashi DEGUCHI, Minoru KANEMATSU, Yoshihit ...1984 Volume 58 Issue 1 Pages 29-38
Published: January 20, 1984
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSIt was attempted to isolate Chlamydia trachomatis from a variety of male and female patients with urethritis who attended urologic clinic.
Cycloheximide-treated McCoy cell was used for isolation of C. trachomatis. Chlamydial inclusions were detected with Giemsa stain using dark-ground and light-ground microscopy.
In a study of urethral discharge from male C. trachomatis was isolated from 30 (51%) of 59 male with nongonococcal urethritis (NGU) and 22 (22%) of 98 male with gonococcal urethritis (GU). Five (45%) of 11 cases with only extracellular Gram-negative diplococci in their urethral smear, 6 (15%) of 39 cases with ≤ 3 of polymorphonuclear cells per high power field in their urethral secretions, 5 (36%) of 14 cases whose urethral discharges were not observed microscopically, none of 12 cases under chemotherapy, and one (8%) of 13 other genitourinary diseases cases had C. trachomatis. Only one (3%) of 31 control male yielded C. trachomatis.
In a study of female patients C. trachomatis was found from 3 (30%) of 10 partners of male with urethritis, and from 3 (75%) of 4 partners of male with Chlamydia-positive urethritis among these partners. C. trachomatis was also recovered from one (6%) of 17 urethral syndrome cases but ont from 3 cases under chemotherapy nor from 2 healthy controls.
Present study would be the first report in Japan to attempt the isolation of C. trachomatis from many of clinical specimens from genitourinary tract of male and female. We have confirmed that in Japan also at least half of NGU and about one fifth of GU patients are infected with C. trachomatis.View full abstractDownload PDF (3271K) -
Distribution of Streptococcus pneumoniae in JapanHideo FUKUMI, Yoshinori KANEKO, Tosihiko AGATA, Makiko TAKAYANAGI, Haj ...1984 Volume 58 Issue 1 Pages 39-53
Published: January 20, 1984
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSStreptococcus pneumoniae isolated in various parts of Japan from a total of 590 patients with identified or putative pneumococcal infections were typed using type-specific antisera during the three years from April, 1980 to March, 1983.
The results obtained were as follows:
1) The 590 identified isolates belonged to 43 Danish types and the rank order of isolates was: Type 3 (12.7%), 19 F (9.3%), 23 F (6.8%), 6 B (5.9%), 6 A (5.9%), 14 (4.9%), 11 A (4.1%), 19 A (3.7%), 9 V (3.6%), 22 F (3.1%) and others.
2) A total of 430 isolates (72.9%) belonged to one of the 23 pneumococcal types to be included in the commercial 23-valent pneumococcal polysaccharide vaccine and 160 isolates (27.1%) were types not be included in the vaccine. The rates of isolation of vaccine-type pneumococci were 76.2% for blood, CSF, transtracheal aspirate (TTA) and others, 66.9% for sputum and throat swabs, 90.5% for middle ear effusions, 79.1% for meningitis and septicemia, 66.9% for respiratory tract infections, and 89.3% for otitis media.
When the nonvaccine-type 6 A which is known to cross-react with type 6 B antibody in humans is included, the total number of vaccine-type pneumococcal isolates was 465 (78.8%), and the rates of isolation of vaccine-type pneumococci were 83.3% for blood, CSF, TTA and others, 73.3% for sputum and throat swabs, 91.9% for middle ear effusions, 87.0% for meningitis and septicemia, 71.9% for respiratory tract infections, and 92.0% for otitis media.
It seems that there is no variation depending on the distribution by type of the pneumococcal isolates according to age and region.View full abstractDownload PDF (1408K) -
Kenji TAKAMATSU, Osamu MIYAMOTO, Masaki NISHIMOTO, Kohtaro FURUKAWA, I ...1984 Volume 58 Issue 1 Pages 54-59
Published: January 20, 1984
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSA 64-years-old man, who had been living a usual daily life, suddenly fell into the state of shock and died almost two hours aftee admission to our hospital. The patient did not develop fever or subcutaneous hemorrhage from the beginning. Since CT revealed subarachnoid hemorrhage, thecause of his death was considered to be subarachnoid hemorrhage. Autopsy performed one hour and a half after death disclosed that Gram-negative diplococci, which seemed to be Neisseria meningitidis, fulled the small blood vessels of various organs in large quantities. A part of these microorganisms were phagocyted by neutrophils in peripheral blood vessels.
However, each tissue presented extremely poor inflammatory reaction and meningitis was not observed. Macroscopic hemorrhage was seen in the arachnoidea, lung, pleura, subendocardial layer, gastrointestinal mucosa, and adrenal cortex. On the basis of the above findings, Waterhouse-Friderichsen syndrome (WFS) due to fulminant meningococcemia was proven.
In Japan, no authors have reported the onset of WFS above 60 years. The clinical picture of this old aged patient was atypical and very fulminant, and the pathohistological picture was peculiar.View full abstractDownload PDF (6444K) -
Kei NUMAZAKI, Shunzo CHIBA, Kazuaki MITO, Takashi HONJO, Tetsuya TSUDA ...1984 Volume 58 Issue 1 Pages 60-65
Published: January 20, 1984
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSA 3-months-old boy was admitted to our hospital with a week history of cough and episodes of rapid breathing and conjunctivitis. At the time of admission the infant had moderate respiratory distress. A chest rentgenogram showed a miliary pneumonic pattern. Chlamydia trachomatis was isolated from nasopharyngeal swab on admission. In addition, IgM antibody response to C. trachomatis was demonstrated by indirect immunofluorescence. At 10 days of illness, the second episode with cough and respiratory distress occured whereas pneumonic infiltration markedly improved. At that time respiratory syncytial (RS) virus was isolated.View full abstractDownload PDF (6418K) -
1984 Volume 58 Issue 1 Pages 82-84
Published: January 20, 1984
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSDownload PDF (317K)
- |<
- <
- 1
- >
- >|