巻号一覧
前身誌
78 巻, 12 号
選択された号の論文の8件中1～8を表示しています
- |<
- <
- 1
- >
- >|
-
小杉 依子, 石川 貴敏, 千村 百合, 安中 めぐみ, 柴崎 澄枝, 安達 桂子, 樋口 浩, 新開 敬行, 貞升 健志, 増田 義重, ...2004 年 78 巻 12 号 p. 995-999
発行日: 2004/12/20
公開日: 2011/02/07
ジャーナル フリーインフルエンザ患者を入院させると, 院内感染による病棟内での流行を引き起こしやすい. これを防止するために, 約700床の病院において, インフルエンザ患者を専用病室 (2室・10床) に3日間以上隔離し, ノイラミニダーゼ阻害薬を服用させた. 2002～2003の流行期間中, 男性21名, 女性32名, 平均年齢78.8歳が入院した. 36例が細菌感染症の合併を疑われ, 抗菌薬の投与を受けた. 血管内留置カテーテル感染を併発した1例以外は, 平均10.7日の入院で, 軽快退院した. これらの処置により, 入院患者に端を発する院内流行は見られなかった. 2症例において, 12時間ごとの気道分泌物中のインフルエンザウイルス排出状況を検討したが, 3日以内で消失しており, 3日間の隔離期間は妥当と考えられた.抄録全体を表示PDF形式でダウンロード (1044K) -
磯部 順子, 木全 恵子, 霜島 正浩, 細呂木 志保, 田中 大祐, 刑部 陽宅2004 年 78 巻 12 号 p. 1000-1005
発行日: 2004/12/20
公開日: 2011/02/07
ジャーナル フリー志賀毒素を産生する大腸菌O128: HNMが, 2002年7月, 下痢, 腹痛, 粘血便を呈する1歳の男児から, 1997年6月, 下痢, 発熱, 嘔吐を呈する11カ月の女児から, それぞれ検出された. 分離菌はいずれも遺伝子stx2fとeaeAを保有していた. しかし, 遺伝子stx1, stx2, aggR, bfpA, esth, estp, invE, astA, ureC, hlyAを保有していなかった. 患者からサルモネラなどの腸管系病原菌は検出されなかった. 下痢患者からのstx2f保有大腸菌O128: HNMの分離は国内で初めてと思われる.抄録全体を表示PDF形式でダウンロード (2846K) -
遺伝子型および薬剤耐性の比較清水 俊夫, 立石 ひとみ, Ahmed SHERIN, 太田 房雄2004 年 78 巻 12 号 p. 1006-1015
発行日: 2004/12/20
公開日: 2011/05/20
ジャーナル フリー2001年8月から2002年6月の間 (以下2001～2002) に分離されたA群溶血性レンサ球菌62株について, T血清型別, 発赤毒遺伝子および薬剤耐性を調査し, 1991年4月から12月の間に分離され, 当所で保存していた臨床由来株61株と比較した.
T血清型別では, 1991年にはT4型が18株と最も多く, 次いでT12型とT1型が15株ずつ分離された. これらの3血清型で全体の78.7%を占めていた. 2001～2002年にはT28型が13株, T1型12株, T4型7株等が検出された.
発赤毒遺伝子については, 検査したすべての菌株がspe B遺伝子を有し, 1991年, 2001～2002年ともに過半数の菌株がspe Bとspe Cの二つの遺伝子を有していた.
1991年分離菌株のうち, T4血清型でspe Bとspe C (以下spe B, C) を有する株が15株, T12型でspe B, Cを有するものが11株, T1型でspe A, Bが9株 (14.8%) あった. 2001～2002年には, T28型でspe B, Cが11株, T1型でspe B, Cが6株, T4でspe B, CとT12でspe B, Cが5株ずつ分離された.
Sma I処理・パルスフィールド電気泳動法による制限酵素切断パターンの解析により, 2001～2002年のT4型spe B, C及びT12型spe B, Cのバンドパターンは1991年に分離されたそれぞれのバンドパターンの一つと同じであることが分った.
過去10年間にマクロライド耐性菌が1株 (1.6%) から11株 (17.7%) に, TC (テトラサイクリン) 耐性菌は23株 (37.7%) から32株 (51.6%) に, 多剤耐性菌は9株 (14.7%) から14株 (22.5%) にそれぞれ増加した.抄録全体を表示PDF形式でダウンロード (3296K) -
横山 栄二, 鶴岡 成一, 斉藤 佳子, 一戸 貞人2004 年 78 巻 12 号 p. 1016-1019
発行日: 2004/12/20
公開日: 2011/02/07
ジャーナル フリーWe are reporting a case of sealed rupture of thoracoabdominal aortic aneurysm associated with the isolation of Listeria monocytogenes. The patient was a 75-year-old man with previous history of hypertension that had not required medication for the 3 years prior to hospital admission. He was admitted due to chest pain, but he was afebrile. There were no clinical findings indicating infection, although CRP was slightly elevated. During his clinical course, a sealed rupture of a thoracoabdominal aortic aneurysm was found and replaced with an artificial artery. After surgery, he was treated for 2 weeks with sultamicillin. He was discharged from hospital on the 43rd postoperative day. No bacteria were observed after microscopic examination of gram stained samples from the thrombus that was present in the sealed rupture of the aneurysm. However, a L. monocytogenes strain isolated from the thrombus only after enrichment culturing by HK medium at 37°C for 4 days. By histopathology, there was a slight cellular infiltration of lymphocytes and neutrophils at the aperture of the aneurysm. Although L. monocytogenes strains possess major pathogenic genes, such as prfA, hlyA, plcA, plcB, mpl, inlA, inlB and actA that can be identified by PCR, none of the evidence indicated that this case was a mycotic aortic aneurysm due to L. monocytogenes.抄録全体を表示PDF形式でダウンロード (4268K) -
原田 和歌子, 桑原 正雄, 桑山 勝, 高尾 信一, 宮崎 佳都夫2004 年 78 巻 12 号 p. 1020-1025
発行日: 2004/12/20
公開日: 2011/02/07
ジャーナル フリーWe discussed the clinical features of 5 Japanese encephalitis (JE) cases which we experienced in 2002.
Today there are few opportunities for a clinician to see JE patients. Until the 1950s, the number of JE patients was more than 2000 in Japan, but the annual cases of JE are decreasing remarkably due to the extermination of mosquitoes, thorough vaccination and improvement of environmental sanitation.
However, even today the disease still has a high fatality rate. In fact 4 in 5 cases we experienced had poor prognosis and one of them resulted in death despite the relatively early diagnosis. It shows the difficulty of diagnosis and treatment.
When we see elderly patients with high fever, headache, and impaired consciousness in late summer and autumn, the important thing is to recognize the possibility of JE. Moreover it turned out that brain MRI and detecting serologic JE virus antibodies was very helpful for diagnosis and treatment.
Nowadays we clinicians tend to consider JE as a disease of the past in Japan, however, this experience taught us that it is necessary for us to study JE again and to continue educating the public about it.抄録全体を表示PDF形式でダウンロード (5646K) -
中村 功, 国広 誠子, 加藤 はる2004 年 78 巻 12 号 p. 1026-1030
発行日: 2004/12/20
公開日: 2011/02/07
ジャーナル フリーWe describe a case of bacteremia due to Clostridium difficile, which was successfully treated by intravenous vancomycin.
A 69-year-old woman was admitted to our hospital because of third degree burn injuries. She was treated with cefazolin for two weeks followed with flomoxef for one week before the operation (debridement and grafting of skin). On the third postoperative day high fever (temperature 40°C), abdominal pain and severe watery diarrhea developed. Antibiotic-associated colitis with bacteremia was diagnosed presumptively, flomoxef was stopped, and oral and intravenous therapy with vancomycin was started. A blood culture taken before the administration of vancomycin yielded C. difficile accompanied with Enterococcus faecalis and Enetrococcus casseliflavus. A stool culture taken on the next day yielded C. difficile, and a stool latex agglutination test was also positive. The patient improved slowly. Parenteral vancomycin was discontinued after two weeks. One week later, the patient developed pneumonia, and imipenem/cilastatin was added. Soon after addition of the agent, she developed recurrent diarrhea despite continual oral vancomycin therapy. The fecal samples obtained at this time were positive for C. difficile by culture and positive for toxins A & B. She was satisfactorily treated with oral vancomycin for a total of four weeks. After the following two weeks, however, recurrencee of diarrhea developed again, which rapidly decreased with oral vancomycin for seven days. The patient did well thereafter and was discharged.
All three C. difficile isolates from blood and fecal specimens were positive for toxins A & B, and identified the same PCR ribotyping pattern.抄録全体を表示PDF形式でダウンロード (1872K) -
宇野 芳史2004 年 78 巻 12 号 p. 1031-1035
発行日: 2004/12/20
公開日: 2011/02/07
ジャーナル フリーA 10-year-old male demonstrating otitis media with effusion by Mycoplasma pneumoniae is reported. The patient was brought to my hospital because of hearing disturbance. β-lactam antibiotics were not effective and we performed a tympanotomy. Microbacterial materials were obtained from the middle ear effusion and nasopharynx. Mycoplasma pneumoniae was detected by the PCR method from both materials and antibody to Mycoplasema pneumoniae was also detected. It is very rare for otitis media with effusion due to Mycoplasma pneumoniae to occur without pneumonia. It is reported that some cases of otitis media with effusion have demonstrated good results by long-term low-dosemacrolide therapy. We believe some of these cases were caused by Mycoplaema pneumoniae.抄録全体を表示PDF形式でダウンロード (2206K) -
床島 眞紀, 芦谷 淳一, 中里 雅光2004 年 78 巻 12 号 p. 1036-1040
発行日: 2004/12/20
公開日: 2011/02/07
ジャーナル フリーA 50-year-old male, living in the rural distinct of Kagoshima Prefecture complained of high fever and fatigue. Chest X-ray showed ground glass opacities in the right lung field. His symptoms and radiographic findings were gradually improved by intravenous or per os administraions of some antibiotics intravenously or per os. Following the chest computed tomography one month later demonstrated ground glass opacities in the right lung field. Examinations of peripheral blood showed increased IgE level but no eosinophila. Bronchoalveolar lavage fluid obtained from B4 showed high proportion of eosinophils. Because of the positive finding for Ascaris suum in the assay of multi dot-ELISA for parasite, he was diagnosed as Ascaris suum infection. The patient was successfully treated with Alvendazol. This is a rare case of Ascaris suum infection causing eosinophilic pneumonia.抄録全体を表示PDF形式でダウンロード (4521K)
- |<
- <
- 1
- >
- >|