Kansenshogaku Zasshi
Online ISSN : 1884-569X
Print ISSN : 0387-5911
ISSN-L : 0387-5911
Volume 82, Issue 2
Displaying 1-7 of 7 articles from this issue
  • Itsuko HORIGUCHI, Tomoko KASHIWAGI, Eiji MARUI
    2008 Volume 82 Issue 2 Pages 67-72
    Published: March 20, 2008
    Released on J-STAGE: February 07, 2011
    JOURNAL FREE ACCESS
    Objective: We studied which infections would be prioritized in educating the general population of Japan.
    Materials and Methods: Subjects were 25 physicians and veterinarians in charge of infection control in infections control divisions of local and national governments. We conducted a questionnaire using the Delphi method.
    Results: Based on (1) epidemiological and clinical characteristics, (2) knowledge level, awareness, and behavior of general population and healthcare professionals, and (3) social background and coping skills we selected 24 diseases for prioritization Tuberculosis was first, followed by influenza, HIV/AIDS, enterohemorrhagic Escherichia coli infection (0157), and genital chlamydial infection. Three animal-derived infections ranked in the top 10.
    Discussion: We have not yet found which the priority of infections should be prioritized in educating the general population on infections. Although our findings are too few to make any generations about, several studies back the reasons why diseases were singled out in our study. Given the fact that most highranked infections have ever been educated, education thus far appears to have been highly ineffective way, meaning that more effective ways of education on infection must be found in future.
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  • Eri HAGIWARA, Akimasa SEKINE, Tomohide SATO, Tomohisa BABA, Takeshi SH ...
    2008 Volume 82 Issue 2 Pages 73-76
    Published: March 20, 2008
    Released on J-STAGE: February 07, 2011
    JOURNAL FREE ACCESS
    A 39-year-old man with dyspnea was revealed to have severe pneumothorax and received partial resection of the left upper lobe after unsuccessful drainage. Necrotizing epitheloid granuloma was found in the resected lung and Mycobacterium fortuitum was detected from the lesion. Chemotherapy with levofloxacin and clarithromycin was started one year after surgery because of the newly found nodular shadow near the lesion. The case experienced pyothorax due to pulmonary tuberculosis three years before and Mycobacterium avium pleuritis one year before this episode. Three-time mycobacterial pleural infection in three years seems to be uncommon. Furthermore this is the first report of pneumothorax associated with pulmonary Mycobacterium fortuitum infection.
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  • The Second Fatal Case in Japan
    Kayoko WADA, Hiroshi SAKAEDA, Rei AONO, Seizou CHIYA
    2008 Volume 82 Issue 2 Pages 77-81
    Published: March 20, 2008
    Released on J-STAGE: February 07, 2011
    JOURNAL FREE ACCESS
    A 77 year-old woman who have no past history, was admitted in a local hospital in Muroto City, Kochi, Japan, after several days of fever and severe general fatigue and generalized skin erythema. She was suspected to haveJapanease spotted fever, which was a local pandemic disease. She was treated with minocycline immediately. The next day, she had consciousness disturbance and low blood pressure. Laboratory findings indicated disseminated intravascular coagulation (DIC) and multiple organ failure. She was referred to our hospital. An eschar was identified in the back of lt. femur. Treatment included minocycline, ciprofloxain, gabexate mesilate, methylprednisolone, hemodialysis and mechanical ventilation. In spite of the avobe treatment, she died 3 days after admission of the local hospital. Though the serological test showed no positive antibody titer against Rickettsia japonica, Rickettsia japonica was isoleted from blood culture, to confirmJapanease spotted fever.Japanease spotted fever is generaly a curative disease with early diagnosis and minocycline. In this case, the patient died 3 days after proper diagnosis and treatment was started. We reported the second fatal Japanease spotted fever case in japan.
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  • Mitsuru KONISHI, Shinsuke YONEKAWA, Chiyo NAKAGAWA, Kenji UNO, Kei KAS ...
    2008 Volume 82 Issue 2 Pages 82-85
    Published: March 20, 2008
    Released on J-STAGE: February 07, 2011
    JOURNAL FREE ACCESS
    A 69-year-old man treated with corticosteroids and immunosuppressive agents for acutely exacerbated interstitial pneumonia was found to have an ingrown nail in the left big toe and that suppurated despite treatment by dermatologists. Culture of the pus expressed from the toe yielded Scedosporium apiospermum. The patient suffered liver dysfunction a few days later when treated with intravenous voriconazole (VRCZ), which was discontinued due to the high plasma VRCZ concentration. Discrete erythema and subcutaneous nodules developed in left leg 2 or 3 weeks later. Ultrasonography showed tubular structures with substantial echoes that were not connected to veins in the subcutaneous tissue of the left leg. These findings suggested a nodular lymphangitic pattern of spreading of S. apiospermum soft tissue infection. Oral VRCZ at 100 mg/day was started, and increased to 200mg/day after the plasma VRCZ concentration was measured. VRCZ was stopped after about 2 months, by which time the man had fully recovered.
    Because VRCZ-induced liver dysfunction was reported significantly associated with plasma level, we treated this case safely by administering VRCZ while measuring the plasma concentration.
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  • Kouichi MASHIBA, Takeshi KOJIMA, Takeshi OOTSUKA, Tomohiro KUSABA
    2008 Volume 82 Issue 2 Pages 86-89
    Published: March 20, 2008
    Released on J-STAGE: February 07, 2011
    JOURNAL FREE ACCESS
    We report a case ofYersinia pseudotuberculosis (Y. pseudotuberculosis) septicemia in a healthy 22-year-old woman with clinical manifestations including high fever and general fatigue. The patient's ferer sudden elevation of her fever, and, liver damage and elevated inflammatory markers were indicated. General fatigue and appetite loss were noted on hospitalization. Exanthema was recognized, and all oral medications, including antibiotics, was stopped. The fever continued and high inflammatory parameters developed. After chemotherapy with imipenem, subjective symptoms ameliorated. Membranous desquamation without itching appeared between the fingers of both hands but improved naturally.
    Y. psuedotuberculosissepticemia was diagnosed asY. psuedotuberculosisisolated from blood and elevated serum antibody titer againstY. psuedotuberculosis4b detected at 1: 160.
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  • Kenichi IZUMI, Takahiro TAKUMA, Takanori OKADA, Masataka NISHIYAMA, Ei ...
    2008 Volume 82 Issue 2 Pages 90-93
    Published: March 20, 2008
    Released on J-STAGE: February 07, 2011
    JOURNAL FREE ACCESS
    We report a rare case of multiple vertebral osteomyelitis due to Streptococcus pneumoniae.
    A 73 year-old man admitted for back pain and a low-grade fever was found in laboratory studies to have severe leukocytosis and increased C-reactive protein, but neither computed tomography (CT) nor vertebral magnetic resonance imaging (MRI) clarified the cause of infection in the painful hip lesion, and paralysis developed. in the left leg MRI eventually indicated a vertebral abscess involving multiple lesions at C4-7 and L4-5.
    We had started antibiotics before blood culture clarified Streptococcus pneumoniae, and antibiotics acted more effectively thereafter. The clinical course was good, little paralysis remained.
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  • 2008 Volume 82 Issue 2 Pages 155
    Published: 2008
    Released on J-STAGE: February 07, 2011
    JOURNAL FREE ACCESS
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